公开(公告)号：US07186277B2

公开(公告)日：2007-03-06

申请号：US10807167

申请日：2004-03-24

申请人： Alain Genet ,  Stéphane Sabelle

发明人： Alain Genet ,  Stéphane Sabelle

IPC分类号： A61K7/13

CPC分类号： C07D295/135 ,  A61K8/494 ,  A61Q5/10 ,  C07D243/08 ,  C07D295/13 ,  C07D295/15

摘要： In one embodiment, the disclosure relates to a composition for dyeing keratin fibres, for example, human keratin fibres such as the hair, comprising at least one para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring, the nitrogen in position 4 of which is a quaternary ammonium. The present disclosure may make it possible, for example, to obtain at least one of chromatic, strong, relatively unselective, fast coloration of keratin fibres.

摘要翻译： 在一个实施方案中，本公开涉及用于染色角蛋白纤维的组合物，例如人角蛋白纤维如毛发，其包含至少一个被二氮杂环己烷或二氮杂环庚烷环取代的对苯二胺衍生物，其中位置4的氮是 季铵。 本公开可以使得例如获得角蛋白纤维的彩色，强烈，相对不选择性，快速着色中的至少一种成为可能。

公开(公告)号：US20050066451A1

公开(公告)日：2005-03-31

申请号：US10807162

申请日：2004-03-24

申请人： Stephane Sabelle ,  Alain Genet ,  Madeleine Leduc

发明人： Stephane Sabelle ,  Alain Genet ,  Madeleine Leduc

IPC分类号： C07D233/54 ,  C07D243/08 ,  C07D295/13 ,  C07D403/06 ,  A61K7/13

CPC分类号： C07D295/13 ,  C07D233/54 ,  C07D243/08 ,  C07D403/06

摘要： The disclosure relates to novel para-phenylenediamine derivatives containing a cyclic diaza group, substituted with a cationic radical, as well as to the dye compositions comprising them, and to the method of dyeing keratin fibers using these compositions. Tthe present invention may make it possible to obtain a chromatic, strong, relatively unselective and fast coloration on keratin fibers.

摘要翻译： 本公开涉及包含被阳离子基团取代的环状二氮杂基团的新型对苯二胺衍生物以及包含它们的染料组合物以及使用这些组合物染色角蛋白纤维的方法。 本发明可以在角蛋白纤维上获得彩色，强烈，相对不选择和快速着色的可能性。

公开(公告)号：US5503640A

公开(公告)日：1996-04-02

申请号：US249923

申请日：1994-05-26

申请人： Alex Junino ,  Alain Genet ,  Gerard Lang

发明人： Alex Junino ,  Alain Genet ,  Gerard Lang

IPC分类号： A61K8/00 ,  A61K8/33 ,  A61K8/40 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61Q5/10 ,  C07C205/37 ,  C07C217/26 ,  C07C217/84 ,  C07C323/36 ,  D06P3/00 ,  A61K7/13 ,  C07C211/00

CPC分类号： A61K8/415 ,  A61Q5/10 ,  C07C205/37 ,  C07C217/84 ,  C07C323/36

摘要： 3-Substituted para-aminophenols of general formula: ##STR1## where X=H, halogen; Y=O--, --S--; R=alkyl, hydroxyalkyl, C.sub.1-4 aminoalkyl or C.sub.3 -C.sub.6 polyhydroxyalkyl;with the proviso that, when X=H, R is not methyl, and when X=H and Y=O, R is not ethyl;process for preparing them, intermediate compounds of formula: ##STR2## where X.sub.1 =halogen, Y and R have the meaning stated above; with the proviso that, when Y=O, R is not methyl, and when R=aminoalkyl, X.sub.1 can also denote hydrogen;dyeing compositions containing one or more compounds of formula (I), and a process For dyeing human hair.

摘要翻译： 3-取代的对位氨基苯酚，其通式如下：其中X = H，卤素; Y = O-，-S-; R =烷基，羟基烷基，C 1-4氨基烷基或C 3 -C 6多羟基烷基; 条件是当X = H时，R不是甲基，当X = H且Y = O时，R不是乙基; 制备它们的方法，式中的中间体化合物：其中X1 =卤素，Y和R具有上述含义; 条件是当Y = O时，R不是甲基，当R =氨基烷基时，X1也可以表示氢; 含有一种或多种式（I）化合物的染色组合物和用于染色人发的方法。

公开(公告)号：US5226924A

公开(公告)日：1993-07-13

申请号：US775101

申请日：1991-10-11

申请人： Alex Junino ,  Alain Genet

发明人： Alex Junino ,  Alain Genet

IPC分类号： A61K8/00 ,  A61K8/33 ,  A61K8/35 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61Q5/10 ,  C09B1/28

CPC分类号： A61K8/355 ,  A61Q5/065 ,  C09B1/285

摘要： The present invention relates to the use of 1,4-di(mono- or poly)hydroxyalkylamino-9,10-anthraquinones: ##STR1## where R represents a C.sub.2 to C.sub.6 monohydroxyalkyl radical or a C.sub.3 to C.sub.6 polyhydroxyalkyl radical for dyeing human keratinous fibers, to the dyeing cosmetic compositions containing such anthraquinones, to the dyeing compositions for keratinous fibers containing such anthraquinones in combination with nitro dyes of the benzene type and azo dyes for direct dyeing, and/or with oxidation dyes for oxidation dyeing as well as to the processes for dyeing keratinous fibers by direct dyeing or by oxidation dyeing.

摘要翻译： 本发明涉及1,4-二（单或多）羟烷基氨基-9,10-蒽醌的用途：其中R表示C2-C6单羟基烷基或C3-C6多羟基烷基，用于 将含有这种蒽醌的染色化妆品组合物染色到含有这种蒽醌的硝酸染料与用于直接染色的偶氮染料组合的角质纤维染色组合物和/或用于氧化染色的氧化染料作为 以及通过直接染色或通过氧化染色染色角质纤维的方法。

公开(公告)号：US5032137A

公开(公告)日：1991-07-16

申请号：US583079

申请日：1990-09-13

申请人： Alex Junino ,  Alain Genet ,  Gerard Lang

发明人： Alex Junino ,  Alain Genet ,  Gerard Lang

IPC分类号： A61K8/00 ,  A61K8/33 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61Q5/10 ,  C07C319/20 ,  C07C323/25 ,  C09B53/00 ,  D06P3/08

CPC分类号： A61Q5/10 ,  A61K8/411 ,  C07C323/25

摘要： The invention relates to p-phenylenediamines of formula: ##STR1## in which R.sub.1 denotes an alkyl, hydroxyalkyl or polyhydroxyalkyl radical and R.sub.2 denotes a hydrogen atom or an alkyl radical, as well as the corresponding salts with acids, and to the compositions and the process for dyeing keratinous fibres, and especially hair, employing them.

公开(公告)号：US5015769A

公开(公告)日：1991-05-14

申请号：US540263

申请日：1990-06-19

申请人： Alex Junino ,  Gerard Lang ,  Alain Genet

发明人： Alex Junino ,  Gerard Lang ,  Alain Genet

IPC分类号： A61K8/00 ,  A61K8/34 ,  A61K8/35 ,  A61K8/40 ,  A61K8/41 ,  A61Q5/06 ,  A61Q5/10 ,  C07C67/00 ,  C07C205/37 ,  C07C213/00 ,  C07C217/84 ,  C07D317/62 ,  C09B51/00 ,  D06P3/04

CPC分类号： A61K8/418 ,  A61Q5/065 ,  C07C205/37 ,  C07D317/62 ,  C09B51/00

摘要： New 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibers, and new intermediate 4,5-dinitrophenols.The present invention relates to a 3-amino-4-nitrophenol of formula: ##STR1## where Z denotes --CH.sub.2 --W, W denoting hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalkoxy(C.sub.1 -C.sub.6)alkyl and R denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl or (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl, the process for preparation thereof and the intermediate compound of formula: ##STR2## in which Z' denotes CH.sub.2 --W, W denoting C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy-(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalcoxy(C.sub.1 -C.sub.6)alkyl.The dyes (I) are useful in direct dyeing of keratinous fibers, in particular human hair.

公开(公告)号：US4729208A

公开(公告)日：1988-03-08

申请号：US65652

申请日：1987-06-25

申请人： Michel Galy ,  Alain Genet

发明人： Michel Galy ,  Alain Genet

IPC分类号： A61M5/00 ,  B65B31/00

CPC分类号： A61M5/00 ,  A61M5/008

摘要： A series of syringe bodies with their lower ends closed is filled with a solution of medicine to a predetermined level in the bodies. The syringe bodies are placed in a lyophilizer with the bodies arranged in a predetermined pattern. A plurality of plungers for the syringe bodies is arranged in a corresponding pattern and above the syringe bodies. After the medicine in the syringe bodies is lyophilized in the lyophilizer, a reduced pressure is created in the lyophilizer and the plungers are simultaneously moved into the syringe bodies to a predetermined level above the lyophilized medicine. The pressure within the lyophilizer is then increased to atmospheric and the assembled syringes are removed. Apparatus for implementing the process can include a lower rack having openings for retaining the syringe bodies in the predetermined pattern, and an upper rack seatable on the lower rack for retaining the piston portions of plungers in facing relation to, aligned with, and above the openings of the syringe bodies. A mechanism within the lyophilizer can be used to simultaneously push the plungers downwardly into the lyophile medicine-containing syringe bodies.

摘要翻译： 将其下端关闭的一系列注射器体填充有药物溶液到体内预定水平。 将注射器体放置在具有以预定图案排列的身体的冻干机中。 用于注射器主体的多个柱塞以相应的图案布置并且在注射器主体上方。 在冷冻干燥机中将注射器体内的药物冻干后，在冻干机中产生减压，同时将柱塞移入注射器主体至冻干药物上方预定的水平。 然后将冻干机内的压力升高至大气压，并将组装的注射器取出。 用于实施该过程的装置可以包括具有用于将注射器主体保持在预定图案中的开口的下部齿条，以及可置于下部齿条上的上部齿条，用于将柱塞的活塞部分保持成与开口对准， 的注射器体。 冻干机内的机构可用于同时将柱塞向下推入含有冻干药物的注射器体内。

公开(公告)号：US4690685A

公开(公告)日：1987-09-01

申请号：US780606

申请日：1985-09-26

申请人： Jean-Francois Grollier ,  Jean Cotteret ,  Alex Junino ,  Alain Genet

发明人： Jean-Francois Grollier ,  Jean Cotteret ,  Alex Junino ,  Alain Genet

IPC分类号： A61K8/00 ,  A61K8/33 ,  A61K8/36 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61Q5/06 ,  A61Q5/10 ,  C09B51/00 ,  C09B67/22 ,  D06P1/19 ,  D06P3/06 ,  A61K7/13

CPC分类号： A61K8/418 ,  A61Q5/065 ,  A61Q5/10 ,  C09B51/00 ,  C09B67/0033 ,  C09B67/0034

摘要： The invention relates to a dyeing composition for keratinous fibres containing at least one 4-bis(.beta.-hydroxyethyl)amino-2-nitro-1-(N-substituted amino)benzene compound in which the substitution is C.sub.1 -C.sub.3 alkyl or .beta.-hydroxyethyl; this composition contains as co-solubilization agent at least one dye of formula (II) ##STR1## in which formula: R.sub.2 denotes a C.sub.2 -C.sub.3 hydroxyalkyl group;R.sub.3 denotes a C.sub.2 -C.sub.3 hydroxyalkyl group; with the proviso that, if R.sub.3 =CH.sub.2 CH.sub.2 OH, R.sub.2 is necessarily an .alpha.-hydroxyethyl or hydroxypropyl radical.

摘要翻译： 本发明涉及含有至少一种4-双（β-羟乙基）氨基-2-硝基-1-（N-取代氨基）苯化合物的角质纤维染色组合物，其中取代为C 1 -C 3烷基或β- 羟乙基 该组合物含有至少一种式（II）染料作为共增溶剂，其中式R2表示C2-C3羟烷基; R3表示C2-C3羟烷基; 条件是如果R3 = CH2CH2OH，则R2必须是α-羟乙基或羟丙基。

公开(公告)号：US07090703B2

公开(公告)日：2006-08-15

申请号：US10807162

申请日：2004-03-24

申请人： Stéphane Sabelle ,  Alain Genet ,  Madeleine Leduc

发明人： Stéphane Sabelle ,  Alain Genet ,  Madeleine Leduc

IPC分类号： A61K7/13

CPC分类号： C07D295/13 ,  C07D233/54 ,  C07D243/08 ,  C07D403/06

摘要： The disclosure relates to novel para-phenylenediamine derivatives containing a cyclic diaza group, substituted with a cationic radical, as well as to the dye compositions comprising them, and to the method of dyeing keratin fibers using these compositions.The present invention may make it possible to obtain a chromatic, strong, relatively unselective and fast coloration on keratin fibers.

摘要翻译： 本公开涉及包含被阳离子基团取代的环状二氮杂基团的新型对苯二胺衍生物以及包含它们的染料组合物以及使用这些组合物染色角蛋白纤维的方法。 本发明可以在角蛋白纤维上获得彩色，坚固，相对不选择和快速着色的可能性。

公开(公告)号：US20060123565A9

公开(公告)日：2006-06-15

申请号：US10807162

申请日：2004-03-24

申请人： Stephane Sabelle ,  Alain Genet ,  Madeleine Leduc

发明人： Stephane Sabelle ,  Alain Genet ,  Madeleine Leduc

IPC分类号： A61K7/13

CPC分类号： C07D295/13 ,  C07D233/54 ,  C07D243/08 ,  C07D403/06

摘要： The disclosure relates to novel para-phenylenediamine derivatives containing a cyclic diaza group, substituted with a cationic radical, as well as to the dye compositions comprising them, and to the method of dyeing keratin fibers using these compositions. Tthe present invention may make it possible to obtain a chromatic, strong, relatively unselective and fast coloration on keratin fibers.

摘要翻译： 本公开涉及包含被阳离子基团取代的环状二氮杂基团的新型对苯二胺衍生物以及包含它们的染料组合物以及使用这些组合物染色角蛋白纤维的方法。 本发明可以在角蛋白纤维上获得彩色，强烈，相对不选择和快速着色的可能性。