公开(公告)号：US20220098604A1

公开(公告)日：2022-03-31

申请号：US17551565

申请日：2021-12-15

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Yanxin SHEN ,  Dongmei XU ,  Jesse FREDERICK ,  Jaemo YANG

IPC: C12N15/82 ,  C07K14/415

Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.

公开(公告)号：US20210360960A1

公开(公告)日：2021-11-25

申请号：US17324969

申请日：2021-05-19

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Robert Franklin HART, III ,  Dongmei XU ,  Marcos Fernando de Godoy LUSSO ,  Jerry Whit MORRIS ,  Kenworth LION ,  Lionel DELOACH

IPC: A24B3/12 ,  A24B15/10

Abstract: The present specification provides for and includes novel methods of curing tobacco to produce desirable smoke and flavor characteristics while reducing the undesirable compounds imparted during a conventional fire-curing process. The present specification provides for and includes cured tobacco having reduced polyaromatic hydrocarbons and TSNA as compared to conventionally fire-cured tobacco. Also provided are tobacco products made with tobacco leaf cured using the disclosed processes.

公开(公告)号：US20210275980A1

公开(公告)日：2021-09-09

申请号：US16838762

申请日：2020-04-02

Applicant: Altria Client Services LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Dongmei XU ,  James Strickland

IPC: B01F13/08 ,  G01N1/38 ,  B01F15/02 ,  B01L3/00 ,  B01F13/00 ,  H02N11/00

Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

公开(公告)号：US20210084852A1

公开(公告)日：2021-03-25

申请号：US17005942

申请日：2020-08-28

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Jesse FREDERICK ,  Yanxin SHEN ,  Dongmei XU ,  Ujwala WAREK ,  James Arthur STRICKLAND

IPC: A01H5/12 ,  C07K14/415 ,  C12N15/82 ,  A01H1/02 ,  A01H1/06 ,  A24B15/20 ,  C12Q1/6895 ,  G01N33/00

Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.

公开(公告)号：US20200170211A1

公开(公告)日：2020-06-04

申请号：US16701872

申请日：2019-12-03

Applicant: Altria Client Services LLC

Inventor： Andrew C. ADAMS ,  Marcos F. de GODOY LUSSO ,  Sreepriya PRAMOD ,  Dongmei XU

IPC: A01H6/82 ,  A01H5/12

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

公开(公告)号：US20160374387A1

公开(公告)日：2016-12-29

申请号：US15192480

申请日：2016-06-24

Applicant: Altria Client Services LLC

Inventor： Andrew Carl ADAMS ,  Marcos Fernando de GODOY LUSSO ,  Sreepriya PRAMOD ,  Dongmei XU

IPC: A24B15/10 ,  A24D1/04 ,  A24D3/04 ,  A24B13/02 ,  A01H5/12 ,  A24B3/12

CPC classification number: A24B15/10 ,  A01H5/12 ,  A24B3/12 ,  A24B13/00 ,  A24B13/02 ,  A24D1/045 ,  A24D3/043 ,  C12N15/8243

Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.

Abstract translation: 本公开提供烟草Nic1基因座的鉴定。 还提供了具有改变的总生物碱和尼古丁水平和商业上可接受的叶子品级，通过育种或转基因方法发展的烟草植物以及来自这些烟草植物的烟草制品的生产。 还提供了用于生产具有新型Nic1突变或等位基因以减少尼古丁水平的烟草植物的组合物和方法。 进一步提供的是序列多态性和分子标记，用于在保持烟叶等级和烟草产品质量的同时养殖烟草，减少尼古丁或尼古丁。