公开(公告)号：US20130338570A1

公开(公告)日：2013-12-19

申请号：US13970675

申请日：2013-08-20

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Jianmin Li ,  Weenna Bucay-Couto

IPC: A61M37/00 ,  A61B17/22

CPC classification number: A61M37/00 ,  A61B10/0241 ,  A61B17/22 ,  A61B17/32002 ,  A61B2017/00274 ,  A61B2017/00685 ,  A61B2017/320775 ,  A61B2018/00547

Abstract: According to an aspect of the present invention, a medical device is provided, which comprises the following: (a) a hollow elongate body (e.g., a elongate cylinder, such as a needle) having distal and proximal ends; and (b) a rotatable member comprising a tissue morselizer and an elongate shaft (e.g., an auger-like tissue-drilling bit). In the devices of the present invention, the elongate shaft is disposed within the hollow elongate body and cooperates with the hollow elongate body to (i) advance material (e.g., morselated tissue) toward the proximal end of the hollow elongate body when the shaft is rotated in a first direction, and (ii) advance material (e.g., a therapeutic agent and/or a bulking agent) toward the distal end of the hollow elongate body when the shaft is rotated in a second direction that is opposite the first direction. According to another aspect of the invention a method of treatment is provided that comprises: (a) inserting the a medical device like that above into the tissue of a patient; (b) morselizing and removing tissue from within the patient while rotating the shaft in a first direction, thereby creating a void within the patient; and (c) introducing a therapeutic agent and/or a bulking agent into the void.

Abstract translation: 根据本发明的一个方面，提供一种医疗装置，其包括：（a）具有远端和近端的中空细长体（例如细长圆柱体，例如针头）; 和（b）可旋转构件，其包括组织修整器和细长轴（例如，螺旋状组织钻头）。 在本发明的装置中，细长轴设置在中空细长主体内并且与中空细长主体配合以（i）当轴是轴向时将材料（例如，微小的组织）推向中空细长体的近端 在第一方向上旋转，并且（ii）当轴沿与第一方向相反的第二方向旋转时，将材料（例如，治疗剂和/或填充剂）推向中空细长体的远端。 根据本发明的另一方面，提供了一种治疗方法，其包括：（a）将如上所述的医疗装置插入患者的组织中; （b）在沿着第一方向旋转所述轴的同时从所述患者内进行细致和去除组织，从而在所述患者体内产生空洞; 和（c）将治疗剂和/或填充剂引入空隙中。

公开(公告)号：US20130190720A1

公开(公告)日：2013-07-25

申请号：US13792346

申请日：2013-03-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： George Bourne ,  Mike Madden ,  Art Madenjian ,  Doreen Rao ,  Marcia Buiser ,  Jianmin Li ,  Raymond Rackley ,  Barry N. Gellman

IPC: A61M5/31

CPC classification number: A61K31/765 ,  A61K9/0024 ,  A61L27/16 ,  A61L27/50 ,  A61M5/31 ,  A61M25/1025 ,  C08L29/04

Abstract: The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, aneurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents.

Abstract translation: 本发明涉及使用所公开的填充剂的填充剂和装置和方法。 填充剂可用于治疗诸如尿和大便失禁，胃食管反流，动脉瘤阻塞和美容畸形的病症。 本发明还涉及减少放置填充剂所需的注射压力的注射方法。

公开(公告)号：US20130118502A1

公开(公告)日：2013-05-16

申请号：US13737004

申请日：2013-01-09

Applicant: Boston Scientific Scimed, Inc.

Inventor： Michael S.H. Chu ,  Jianmin Li ,  Hamid Davoudi

IPC: A61F6/22

CPC classification number: A61F6/225

Abstract: According to one claim of the invention, a method for occluding a fallopian tube in a vertebrate subject is described, which comprises comprising transcervically delivering a solid blocking material into the fallopian tube. In various embodiments, a fluid sealing material is delivered along with the solid blocking material. Other claims of the invention pertain to articles of manufacture, delivery devices and kits for use in occluding the fallopian tubes of a vertebrate subject.

Abstract translation: 根据本发明的一个权利要求，描述了一种用于在脊椎动物受试者中闭塞输卵管的方法，其包括将固体阻塞材料递送到输卵管中。 在各种实施例中，流体密封材料与固体阻挡材料一起被输送。 本发明的其它权利要求涉及用于阻塞脊椎动物对象的输卵管的制品，递送装置和试剂盒。