公开(公告)号：US20240358417A1

公开(公告)日：2024-10-31

申请号：US18770157

申请日：2024-07-11

申请人： MediCarbone, Inc.

发明人： Ravichandran Kollarigowda ,  Krishna Kolan ,  Neda Saadatmanesh ,  Hamid Saadatmanesh ,  Abiraman Srinivasan

IPC分类号： A61B17/72 ,  A61B17/56 ,  A61B17/68 ,  A61B17/88 ,  A61L15/12 ,  A61L15/14 ,  A61L27/12 ,  A61L27/16

CPC分类号： A61B17/7258 ,  A61B17/68 ,  A61B17/8805 ,  A61B17/8836 ,  A61B17/8858 ,  A61L15/125 ,  A61L15/14 ,  A61L27/12 ,  A61L27/16 ,  A61B2017/564 ,  A61B2017/568 ,  A61L2400/06 ,  A61L2430/02

摘要： A photocurable device injection system for creating in situ polymerization via light or free-radical to enable fractured bone fixation. The system comprises a photosensitive polymeric resin sensitive to light, temperature, oxygen, enzymes, or a combination thereof. The photosensitive polymeric resin may be configured to cure at room temperature or physiological temperature with a light source. The photosensitive polymeric resin may be configured to depolymerize with ultrasonication, sonication, or a combination thereof. The system further comprises an implantable 3-dimensional biocompatible pouch comprising an optical light guide. The system further comprises one or more micro-sized ultrasonication probes configured to contact a three-dimensional pouch by one or more openings. The one or more probes may be configured to enable polymer outflow.

公开(公告)号：US12128157B2

公开(公告)日：2024-10-29

申请号：US17358041

申请日：2021-06-25

申请人： The Procter & Gamble Company

发明人： Maxwell Joseph Wingert ,  Josef Breu ,  Lina Mayr ,  Steven Ray Merrigan ,  Arsen Arsenov Simonyan

IPC分类号： A61L27/56 ,  A61F13/472 ,  A61F13/535 ,  A61L15/18 ,  A61L15/42 ,  A61L27/04 ,  A61L27/16 ,  A61F13/53

CPC分类号： A61L27/56 ,  A61F13/472 ,  A61F13/535 ,  A61L15/18 ,  A61L15/425 ,  A61L27/047 ,  A61L27/16 ,  A61F2013/530817 ,  A61L2400/12

摘要： Open-cell foam having a structure of interconnected struts formed of polymeric material and defining open cells, resulting from polymerization of a continuous phase of a high internal phase water-in-oil emulsion, the struts comprising the polymeric material with clay nanoparticles at least partially captured therewithin, is disclosed. The clay nanoparticles may be present in combination with a surface modifier. Methods for making the open-cell foam are also disclosed. Absorbent articles including the open cell foam are also disclosed.

公开(公告)号：US12109151B2

公开(公告)日：2024-10-08

申请号：US18145020

申请日：2022-12-22

申请人： AMO Development, LLC

发明人： Richard Hofer ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Phillip Gooding ,  Georg Schuele

IPC分类号： A61F9/008 ,  A61L27/16 ,  A61B17/00

CPC分类号： A61F9/00827 ,  A61F9/00834 ,  A61L27/16 ,  A61B2017/00061 ,  A61B2017/00154 ,  A61F2009/00844 ,  A61F2009/00851 ,  A61F2009/00897 ,  A61L2430/16

摘要： Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.

公开(公告)号：US12103992B2

公开(公告)日：2024-10-01

申请号：US15734039

申请日：2019-05-21

申请人： Shanghai Fulo Medical Instrument Co., Ltd.

发明人： Mototora Kai

IPC分类号： C08F20/44 ,  A61L27/14 ,  A61L27/16 ,  A61L27/50 ,  C08F20/14 ,  C08F20/26 ,  C08F20/30 ,  A61F2/16

CPC分类号： C08F20/30 ,  A61L27/16 ,  A61L27/50 ,  C08F20/14 ,  A61F2002/16965 ,  A61L2430/16

摘要： A polymer material is provided that can be used to produce an intraocular lens having a high refractive index and low adhesion on a lens surface and suppressing the occurrence of glistening and sub-surface nano glistening. Further, an intraocular lens with the properties mentioned above is provided. The polymer material can preferably be used to produce an intraocular lens. The polymer material is formed by polymerizing a liquid monomer mixture containing 11 to 30% by mass of a macromonomer (A) represented by the following formula (I) and at least a (meth)acrylate monomer (B) with an aryl group.






[In the formula, four n respectively and individually representing 1 or 2, a, b, c, and d being respectively and individually integers of 4 or more, and four Z being respectively and individually substituent groups containing a (meth)acryloyl group.]

公开(公告)号：US20240293114A1

公开(公告)日：2024-09-05

申请号：US18590433

申请日：2024-02-28

申请人： Silara Medtech Inc.

发明人： Travis ROWE ,  Trevor M. GREENAN ,  Luis A. HERNANDEZ ,  Saleen SHARMA

IPC分类号： A61B17/04 ,  A61B90/00 ,  A61F2/24 ,  A61L27/16 ,  A61L27/48 ,  A61L31/02

CPC分类号： A61B17/0467 ,  A61B17/0469 ,  A61F2/2454 ,  A61F2/2466 ,  A61L27/16 ,  A61L27/48 ,  A61L31/024 ,  A61B2090/034 ,  A61F2220/0075 ,  A61F2250/0098

摘要： A tether cutting system for transcatheter annuloplasty may be provided with a flexible catheter, a handle section coupled to the proximal end of the catheter having a movable actuator, and a cutter assembly coupled to the distal end of the catheter. The cutter assembly may be provided with a blade coupled to a blade holder, a slot configured to slidably receive a tether to be cut, and a backstop configured to contact the blade. The system may further include a pull wire extending through the catheter, spanning between the movable actuator and the blade holder. In one embodiment, the movable actuator, the pull wire and the blade holder are configured to cooperate together to move the blade from a distal position, across the cutter assembly slot and towards a proximal position to cut a tether extending through the slot. Methods of use are also provided.

公开(公告)号：US20240207486A1

公开(公告)日：2024-06-27

申请号：US18555184

申请日：2022-04-14

申请人： CORNELL UNIVERSITY

发明人： Minglin MA ,  Longhai WANG ,  Alexander ERNST

IPC分类号： A61L27/38 ,  A61L27/16 ,  A61L27/18 ,  A61L27/20 ,  A61L27/34 ,  A61L27/52

CPC分类号： A61L27/3804 ,  A61L27/16 ,  A61L27/18 ,  A61L27/20 ,  A61L27/34 ,  A61L27/3834 ,  A61L27/52

摘要： Disclosure herein are an implantable cell containing device, its subcomponent scaffold, methods of making the same and their methods of use. The implantable cell containing device includes a scaffold and a cell-containing hydrogel encapsulating the scaffold. The scaffold has a tracheal-like internal system of continuous air-filled, hydrophobic micro-channels that traverse the scaffold's dimensions and a hydrophilic external surface. The implantable cell containing device, when implanted in a subject, can be used for delivering a therapeutic agent to a subject in need thereof for the treatment of various conditions and diseases.

公开(公告)号：US20240191007A1

公开(公告)日：2024-06-13

申请号：US18587211

申请日：2024-02-26

申请人： b-ONE Medical (Suzhou) Co., Ltd. ,  b-ONE Medical Biotech Corporation ,  b-ONE Ortho, Corp

发明人： Zongtao ZHANG

IPC分类号： C08F110/02 ,  A61K31/355 ,  A61L27/16 ,  A61L27/54

CPC分类号： C08F110/02 ,  A61K31/355 ,  A61L27/16 ,  A61L27/54 ,  A61L2430/24 ,  C08F2500/01 ,  C08F2810/20

摘要： The invention relates to a surface gradient cross-linked method of a ultra-high molecular weight polyethylene and the application thereof. The surface gradient crosslinked method of ultrahigh molecular weight polyethylene includes a n ultra-high molecular weight polyethylene surface photoinitiator diffusion step and an ultraviolet light irradiation crosslinking step. In this method, the photoinitiator is diffused deeply into the surface of ultra-high molecular weight polyethylene, the body material shows a gradient cross-linking from the surface to the inside after ultraviolet irradiation so that the whole bulk has a high toughness and the surface there of has a high wear resistance.

公开(公告)号：US20240183081A1

公开(公告)日：2024-06-06

申请号：US18441730

申请日：2024-02-14

申请人： TECRES S.p.A.

发明人： Giovanni FACCIOLI ,  Renzo SOFFIATTI

IPC分类号： D01D5/08 ,  A61L27/16 ,  A61L27/54 ,  B33Y10/00 ,  B33Y70/10

CPC分类号： D01D5/082 ,  A61L27/16 ,  A61L27/54 ,  B33Y10/00 ,  B33Y70/10 ,  A61L2300/104 ,  A61L2300/232 ,  A61L2300/25 ,  A61L2300/406 ,  D10B2321/0211 ,  D10B2401/13 ,  D10B2509/00

摘要： Method for the obtainment of a thread made of a material biocompatible and implantable in the human body: a thread for the obtainment of a device implantable in the human body.

公开(公告)号：US20240139381A1

公开(公告)日：2024-05-02

申请号：US18278608

申请日：2022-02-23

申请人： IVIVA Medical, Inc.

发明人： Charles C. Klassen

IPC分类号： A61L27/56 ,  A61L27/16 ,  A61L27/22 ,  A61L27/24 ,  A61L27/36 ,  A61L27/38 ,  A61L27/48

CPC分类号： A61L27/56 ,  A61L27/16 ,  A61L27/222 ,  A61L27/24 ,  A61L27/3633 ,  A61L27/3804 ,  A61L27/48 ,  A61L2400/18

摘要： Disclosed herein is a conduit embedded with a biocompatible polymer for use in devices such as artificial tissues and organs. Also disclosed are methods of making such conduits.

公开(公告)号：US11970560B2

公开(公告)日：2024-04-30

申请号：US16643736

申请日：2018-09-03

申请人： The University of North Carolina at Chapel Hill

发明人： Sergei Sheiko ,  Mohammad Vatankhah-Varnosfaderani

IPC分类号： C09D153/00 ,  A61L27/16 ,  C08F293/00 ,  C09J153/00

CPC分类号： C08F293/005 ,  A61L27/16 ,  C09D153/00 ,  C09J153/00 ,  C08F2438/01

摘要： The invention generally relates to linear-bottlebrush-linear copolymer blocks and methods of making and using same. The disclosed copolymer blocks can be useful in, for example, the formation of polymer networks that replicate biological stress-strain behavior. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.