公开(公告)号：US20230099978A1

公开(公告)日：2023-03-30

申请号：US18075939

申请日：2022-12-06

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon

IPC: A61F2/24

Abstract: A capsule for a delivery apparatus and associated methods are disclosed. As one example, a capsule can include at least one end portion, arranged at a proximal end or distal end of the capsule, that narrows in diameter from a wider outer diameter of a middle portion of the capsule to a narrower outer diameter at an end of the at least one end portion, the end spaced away from the middle portion, where the at least one end portion is configured to expand to the wider outer diameter in response to a radially outward pressure from the prosthetic medical device during removal of the prosthetic medical device from inside of the capsule.

公开(公告)号：US20220409366A1

公开(公告)日：2022-12-29

申请号：US17901602

申请日：2022-09-01

Applicant: Edwards Lifesciences Corporation

Inventor： Michael Bukin ,  Noam Nir ,  Tamir S. Levi ,  Ziv Yohanan ,  Elena Sherman ,  Eran Goldberg ,  David Maimon

IPC: A61F2/24

Abstract: A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

公开(公告)号：US20220168125A1

公开(公告)日：2022-06-02

申请号：US17673601

申请日：2022-02-16

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noa Axelrod Manela ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

IPC: A61F2/966 ,  A61M25/00 ,  B29D23/00 ,  A61F2/24 ,  A61F2/95

Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

公开(公告)号：US11311399B2

公开(公告)日：2022-04-26

申请号：US16716027

申请日：2019-12-16

Applicant: Edwards Lifesciences Corporation

Inventor： John J. Desrosiers ,  Daniel James Murray ,  Michael G. Valdez ,  Liron Tayeb ,  David Maimon ,  Eitan Atias ,  Adi Carmi

IPC: A61F2/966 ,  A61B17/34 ,  A61F2/24 ,  A61B17/12 ,  A61N1/39

Abstract: Delivery systems and catheters including lock and release connectors for implantable devices and methods for retaining, positioning, and deploying a medical device are disclosed. The lock and release connectors can include a body and at least one door engaged with the body, wherein the door is moveable from a first position to a second position. The lock and release connectors can further include at least one fastener connecting at least one end of the door to the body. The door can be integral with the body or connected and can comprise a shape memory material and/or other materials.

公开(公告)号：US11273036B2

公开(公告)日：2022-03-15

申请号：US16435288

申请日：2019-06-07

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Michael R. Bialas ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Linda Thai ,  Yidong M. Zhu

IPC: A61F2/24 ,  A61F2/958

Abstract: Disclosed herein are embodiments of a balloon shaped to have one or more enlarged recons to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve. This overcomes the stent-mounted prosthetic heart valve's tendency to expand with flared ends. This forms a more cylindrical or barrel shaped stent frame during expansion of the balloon—reducing or eliminating the instance wherein the cylindrical stent frame has flared ends. Alternatively, the balloon may have conical flares placed to cause or enhance flared ends of the cylindrical implant to enhance its anchoring capabilities.

公开(公告)号：US11051939B2

公开(公告)日：2021-07-06

申请号：US16111951

申请日：2018-08-24

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Liron Tayeb

IPC: A61F2/24 ,  A61M25/00 ,  A61F2/95

Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.

公开(公告)号：US20210169630A1

公开(公告)日：2021-06-10

申请号：US17174784

申请日：2021-02-12

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Carmel Peleg ,  Tomer Saar ,  Alexander Barash ,  David Maimon

IPC: A61F2/00 ,  A61F2/24

Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.

公开(公告)号：US10925730B2

公开(公告)日：2021-02-23

申请号：US15956031

申请日：2018-04-18

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Noam Nir ,  Tomer Saar

IPC: A61F2/24

Abstract: A method for improving leaflet prolapse and/or valve regurgitation associated with a heart valve involves delivering a spacer device into a ventricle of a heart using a delivery system comprising a catheter, fixing the spacer device to a wall of the ventricle, expanding the spacer device to reposition a papillary muscle disposed in the ventricle away from the wall, the papillary muscle being connected to a leaflet of an atrioventricular heart valve via chordae tendineae, and releasing the spacer device from the catheter.

公开(公告)号：US20200100895A1

公开(公告)日：2020-04-02

申请号：US16697065

申请日：2019-11-26

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Son V. Nguyen ,  Netanel Benichou ,  David Maimon ,  Ziv Yohanan ,  Nikolay Gurovich ,  Bella Felsen ,  Larisa Dadonkina ,  Ron Sharoni ,  Elena Sherman

IPC: A61F2/24

Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.

公开(公告)号：US10537423B2

公开(公告)日：2020-01-21

申请号：US15194375

申请日：2016-06-27

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Son V. Nguyen ,  Netanel Benichou ,  David Maimon ,  Ziv Yohanan ,  Nikolay Gurovich ,  Bella Felsen ,  Larisa Dadonkina ,  Ron Sharoni ,  Elena Sherman

IPC: A61F2/24

Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.