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公开(公告)号:US20230201015A1
公开(公告)日:2023-06-29
申请号:US18171187
申请日:2023-02-17
发明人: Nikolai Gurovich , Boaz Manash , Adi Carmi , Eran Goldberg , Khen Perlmutter
CPC分类号: A61F2/9522 , A61F2/2418
摘要: A docking station for a prosthetic heart valve includes a radially expandable and collapsible frame with a first plurality of struts, an inflow end portion, an outflow end portion, and a longitudinal axis. A sealing member is disposed on the outflow end portion and configured to form a seal between the docking station and a body lumen. The docking station further includes a valve seat coupled to the frame and configured to receive an expandable prosthetic valve. The valve seat includes a second plurality of struts coupled to the frame and extending in a downstream direction and angled inwardly toward the longitudinal axis of the frame.
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公开(公告)号:US20190000615A1
公开(公告)日:2019-01-03
申请号:US16034794
申请日:2018-07-13
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
IPC分类号: A61F2/24
摘要: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
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公开(公告)号:US20230089738A1
公开(公告)日:2023-03-23
申请号:US17992730
申请日:2022-11-22
发明人: Adi Carmi , Boaz Manash , Nikolai Gurovich , Michael Bukin
IPC分类号: A61F2/24
摘要: A prosthetic valve assembly includes a prosthetic valve and an anchoring frame. The prosthetic valve includes a valve frame and a valve structure. The valve frame includes a plurality of struts and is expandable from a compressed configuration to an expanded configuration. The valvular structure includes leaflets. The valvular structure is disposed radially within and is coupled to the valve frame. The valvular structure is configured to allow blood flow through the prosthetic valve assembly in a first direction and to restrict blood flow through the prosthetic valve assembly in a second direction. The anchoring frame includes a plurality of struts. The anchoring frame is disposed radially outwardly from and is coupled to the valve frame. The struts of the anchoring frame comprise one or more tissue-engaging elements configured for contacting native tissue to help secure the prosthetic valve assembly at an implantation location.
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公开(公告)号:US20220226110A1
公开(公告)日:2022-07-21
申请号:US17657732
申请日:2022-04-01
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eitan Atias
IPC分类号: A61F2/24
摘要: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.
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公开(公告)号:US11083571B2
公开(公告)日:2021-08-10
申请号:US16442165
申请日:2019-06-14
发明人: Boaz Manash , Khen Perlmutter , Adi Carmi , Noa Axelrod , Nikolay Gurovich
IPC分类号: A61F2/24
摘要: A prosthetic heart valve is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. The heart valve includes an annular inner frame formed with a plurality of angled first strut members, the inner frame being configured to foreshorten from a first length corresponding to the collapsed configuration to a second length corresponding to the expanded configuration. A leaflet structure is situated at least partially within the inner frame. An outer frame is disposed radially outward of the inner frame and coupled to the inner frame. The outer frame is configured to collapse with the inner frame and radially expand with the inner frame, and includes a plurality of second strut members. Portions of the second strut members are configured to bend radially outwardly into a curved shape as the inner frame and the outer frame move from the collapsed configuration to the expanded configuration.
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公开(公告)号:US11311399B2
公开(公告)日:2022-04-26
申请号:US16716027
申请日:2019-12-16
发明人: John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Liron Tayeb , David Maimon , Eitan Atias , Adi Carmi
摘要: Delivery systems and catheters including lock and release connectors for implantable devices and methods for retaining, positioning, and deploying a medical device are disclosed. The lock and release connectors can include a body and at least one door engaged with the body, wherein the door is moveable from a first position to a second position. The lock and release connectors can further include at least one fastener connecting at least one end of the door to the body. The door can be integral with the body or connected and can comprise a shape memory material and/or other materials.
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公开(公告)号:US20200000579A1
公开(公告)日:2020-01-02
申请号:US16442165
申请日:2019-06-14
发明人: Boaz Manash , Khen Perlmutter , Adi Carmi , Noa Axelrod , Nikolay Gurovich
IPC分类号: A61F2/24
摘要: A prosthetic heart valve is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. The heart valve includes an annular inner frame formed with a plurality of angled first strut members, the inner frame being configured to foreshorten from a first length corresponding to the collapsed configuration to a second length corresponding to the expanded configuration. A leaflet structure is situated at least partially within the inner frame. An outer frame is disposed radially outward of the inner frame and coupled to the inner frame. The outer frame is configured to collapse with the inner frame and radially expand with the inner frame, and includes a plurality of second strut members. Portions of the second strut members are configured to bend radially outwardly into a curved shape as the inner frame and the outer frame move from the collapsed configuration to the expanded configuration.
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公开(公告)号:US11291540B2
公开(公告)日:2022-04-05
申请号:US16034794
申请日:2018-07-13
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
摘要: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
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公开(公告)号:US20210361417A1
公开(公告)日:2021-11-25
申请号:US17397727
申请日:2021-08-09
IPC分类号: A61F2/24
摘要: A method of treating mitral valve stenosis in a human heart includes advancing a delivery apparatus through a right femoral vein, across a septal wall, and through a calcified mitral valve. A prosthetic heart valve is provided along a distal end portion of the delivery apparatus, wherein the prosthetic heart valve includes a metallic frame having a plurality of tissue-engaging elements positioned along an exterior surface and a leaflet structure for replacing the function of the calcified mitral valve. The prosthetic heart valve is radially expanded within an annulus of the calcified mitral valve such that at least some of the tissue-engaging elements of the prosthetic heart valve embed into the annulus. After radial expansion, the prosthetic heart valve is retained in position within the annulus via the tissue-engaging element and the leaflet structure replaces the function of the native mitral valve.
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