公开(公告)号：US07691139B2

公开(公告)日：2010-04-06

申请号：US11318690

申请日：2005-12-27

申请人： Deborah A. Baker ,  James D. Purdy ,  Fred T. Parker

发明人： Deborah A. Baker ,  James D. Purdy ,  Fred T. Parker

IPC分类号： A61F2/84

CPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2002/9517

摘要： A tubular prosthesis delivery system has an inner tubular member having a distal end including a prosthesis-carrying portion and a proximal end intended to remain outside the patient. An outer tubular member has a distal end spaced from the prosthesis-carrying portion of the inner member. A coupling member couples the inner and outer tubular members to each other in fixed relationship generally at a location intended to remain outside the patient. An intermediate tubular member located between the inner and outer tubular members has a distal end adapted to cover the tubular prosthesis and a proximal end that projects proximally beyond the proximal ends of both the inner and outer tubular members. The proximally projecting end of the intermediate tubular member is longitudinally movable with respect to the coupled inner and outer tubular members by a distance sufficient to retract the intermediate tubular member distal end from any position covering the prosthesis carried by the inner member.

摘要翻译： 管状假体递送系统具有内部管状构件，其具有远端，远端包括假体承载部分和旨在保持在患者体外的近端。 外管状构件具有与内构件的假体承载部分间隔开的远端。 联接构件通常以固定关系将内管状构件和外管状构件彼此联接在旨在保持在患者身体外部的位置。 位于内管状构件和外管状构件之间的中间管状构件具有适于覆盖管状假体的远端和近端突出超过内管状构件和外管状构件的近端的近端。 中间管状构件的近端突出的端部可相对于联接的内部和外部管状构件纵向移动一定距离，足以使中间管状构件远端从覆盖由内部构件承载的假体的任何位置缩回。

公开(公告)号：US20090309273A1

公开(公告)日：2009-12-17

申请号：US12481362

申请日：2009-06-09

申请人： Fred T. Parker

发明人： Fred T. Parker

IPC分类号： B29D23/00

CPC分类号： A61F2/82 ,  A61F2240/001 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16

摘要： A method of making a self-expanding stent includes disposing a stent comprising a shape memory alloy about an inflatable body, and applying a coolant to a surface of the stent. The inflatable body is inflated to radially expand the stent to an expanded diameter from an initial diameter, and the coolant is reapplied to the surface of the stent. The inflatable body is deflated, and the stent is positioned about a mandrel sized to accommodate the expanded diameter of the stent, where the stent reaches a mandrel-defined diameter. The stent is heat set at the mandrel-defined diameter so as to impart a memory of an expanded configuration of the stent to the shape memory alloy.

摘要翻译： 制造自扩张支架的方法包括将包括形状记忆合金的支架围绕可充气体放置，并将冷却剂施加到支架的表面。 将充气体充气以将支架径向膨胀至从初始直径扩张的直径，并将冷却剂重新施加到支架的表面。 充气体被放气，并且支架围绕心轴定位，心轴尺寸适于支架的扩展直径，其中支架达到心轴限定的直径。 将支架热定形在心轴限定的直径处，以便将支架的扩张构型的记忆赋予形状记忆合金。

公开(公告)号：US20090254168A1

公开(公告)日：2009-10-08

申请号：US12487191

申请日：2009-06-18

申请人： Fred T. Parker ,  Palle Hansen ,  Nathaniel A. Irwin

发明人： Fred T. Parker ,  Palle Hansen ,  Nathaniel A. Irwin

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61F2002/9665 ,  A61M2025/0004 ,  A61M2025/0681

摘要： A system for delivery of a medical device to a target site within the body of a patient includes an introducer sheath, and a delivery assembly receivable within a passageway of the sheath. The delivery assembly comprises an inner tubular and an outer tubular member. At least a distal portion of the inner tubular member has a diameter such that the medical device is receivable thereover. The outer tubular member is generally coaxial with the inner tubular member, and has a length such that the outer tubular member distal end terminates proximal to the inner tubular member distal portion. The outer tubular member has a first outer diameter at the proximal end and extends for a length of the outer tubular member to a first diameter boundary point. The outer tubular member has a gradual inward taper in the distal direction from the boundary point to a second outer diameter, and has an abrupt outward taper in the distal direction from the second diameter to the first diameter.

摘要翻译： 用于将医疗装置递送到患者体内的目标部位的系统包括导引鞘，以及可在鞘的通道内接收的输送组件。 输送组件包括内管和外管状构件。 至少内部管状构件的远端部分具有使得医疗装置能够在其上接收的直径。 外部管状构件大致与内部管状构件同轴，并且具有使外部管状构件远端靠近内部管状构件远端部分终止的长度。 外部管状构件在近端具有第一外径并且将外部管状构件的一段长度延伸到第一直径边界点。 外管状构件在从边界点到第二外径的远端方向上具有逐渐向内的锥形，并且在远端方向上具有从第二直径到第一直径的突出向外锥形。

公开(公告)号：US20090171300A1

公开(公告)日：2009-07-02

申请号：US11965210

申请日：2007-12-27

申请人： Fred T. Parker ,  Palle Hansen ,  Nathaniel A. Irwin

发明人： Fred T. Parker ,  Palle Hansen ,  Nathaniel A. Irwin

IPC分类号： A61M25/00

CPC分类号： A61F2/95 ,  A61F2002/9665 ,  A61M2025/0004 ,  A61M2025/0681

摘要： A system for delivery of a medical device to a target site within the body of a patient includes an introducer sheath, and a delivery assembly receivable within a passageway of the sheath. The delivery assembly comprises an inner tubular and an outer tubular member. At least a distal portion of the inner tubular member has a diameter such that the medical device is receivable thereover. The outer tubular member is generally coaxial with the inner tubular member, and has a length such that the outer tubular member distal end terminates proximal to the inner tubular member distal portion. The outer tubular member has a first outer diameter at the proximal end and extends for a length of the outer tubular member to a first diameter boundary point. The outer tubular member has a gradual inward taper in the distal direction from the boundary point to a second outer diameter, and has an abrupt outward taper in the distal direction from the second diameter to the first diameter.

公开(公告)号：US07459042B2

公开(公告)日：2008-12-02

申请号：US11351815

申请日：2006-02-10

申请人： Fred T. Parker

发明人： Fred T. Parker

IPC分类号： C22F1/10

CPC分类号： A61F2/82 ,  A61F2/95 ,  A61F2002/9522

摘要： A method (112) of loading an expandable medical device in a low vapor environment. The method includes placing the device in a loading chamber (114) at, for example, room temperature and removing (116) from the chamber any undesirable contaminants such as water vapor that can form condensation on the device when the device is cooled for compression into a transfer tube or delivery catheter. The temperature in the chamber is lowered (118) to a temperature below the transition temperature (martensitic finish) of the device. The device is compressed (120) below its' transition temperature and loaded (122) into a delivery or transfer device.

摘要翻译： 一种在低蒸汽环境中装载可扩张医疗装置的方法（112）。 该方法包括将装置放置在例如室温的装载室（114）中，并从室中移除（116）任何不期望的污染物，例如水蒸汽，当装置被冷却以压缩时，可以在装置上形成冷凝 转运管或输送导管。 室中的温度降低（118）到低于设备的转变温度（马氏体完成）的温度。 该设备被压缩（120）低于其过渡温度并加载（122）进入传送或传送设备。

公开(公告)号：US20080215131A1

公开(公告)日：2008-09-04

申请号：US11950244

申请日：2007-12-04

申请人： Mark A. Magnuson ,  Fred T. Parker ,  Palle M. Hansen

发明人： Mark A. Magnuson ,  Fred T. Parker ,  Palle M. Hansen

IPC分类号： A61F2/04

CPC分类号： C22F1/006 ,  A61F2/95 ,  A61F2002/9522 ,  A61F2210/0014 ,  A61F2250/0042 ,  C22F1/00 ,  C22F1/10 ,  Y10T29/4976 ,  Y10T29/49865

摘要： A process to load a medical device comprising a shape memory material into a delivery system is described herein. According to one aspect, the method includes applying a force to the medical device to obtain a delivery configuration thereof, where the device is at a first temperature within an R-phase temperature range of the shape memory material during application of the force. The medical device is cooled in the delivery configuration to a second temperature at or below a martensite finish temperature of the shape memory material. The force is then removed from the medical device, and the device is loaded into a delivery system. Preferably, the medical device substantially maintains the delivery configuration during the loading process.

摘要翻译： 本文描述了将包括形状记忆材料的医疗装置加载到递送系统中的过程。 根据一个方面，所述方法包括向所述医疗装置施加力以获得其输送构型，其中所述装置在所述力的施加期间处于所述形状记忆材料的R相温度范围内的第一温度。 医疗装置在输送构型中被冷却到等于或低于形状记忆材料的马氏体终止温度的第二温度。 然后将力从医疗装置中取出，将装置装载到输送系统中。 优选地，医疗装置在装载过程中基本维持输送构型。

公开(公告)号：US5380304A

公开(公告)日：1995-01-10

申请号：US21398

申请日：1993-02-23

申请人： Fred T. Parker

发明人： Fred T. Parker

IPC分类号： A61M25/00 ,  A61M25/06 ,  A61M25/08

CPC分类号： A61M25/0662 ,  A61M25/0012 ,  A61M25/005 ,  B29C43/18 ,  B29C2043/3665 ,  B29K2105/258 ,  B29L2023/00

摘要： A flexible, kink-resistant, introducer sheath for percutaneous vascular access. The introducer sheath includes a flat wire coil with uniform spacing between the turns, which is compression fitted about an inner, lubricous material polytetrafluoroethylene tube. The introducer sheath further includes an outer tube of a heat formable polyamide material which is heat formed and compressed through the spaces between the turns of the wire coil to mechanically connect to the roughened outer surface of the inner tube. The distal end of the outer tube is tapered in a mold with additional polyamide outer tube material. The proximal end of the sheath is flared for connection to a connector fitting. In another aspect of the introducer sheath, the flat wire coil has an inner diameter less than the outer diameter of the inner tube. The coil is then expanded and wrapped around the inner tube to form a compression fit.

摘要翻译： 用于经皮血管通路的柔性，扭结的导引鞘。 引导器鞘包括在匝之间具有均匀间隔的扁线线圈，其围绕内部润滑材料聚四氟乙烯管压缩配合。 引导器护套还包括可热成型的聚酰胺材料的外管，其通过线圈的匝之间的空间热形成和压缩，以机械地连接到内管的粗糙化的外表面。 外管的远端在具有额外的聚酰胺外管材料的模具中成锥形。 护套的近端用于连接到连接器配件。 在导引鞘的另一方面，扁线线圈的内径小于内管的外径。 然后将线圈膨胀并缠绕在内管周围以形成压配合。

公开(公告)号：US09326874B2

公开(公告)日：2016-05-03

申请号：US13264329

申请日：2010-04-12

申请人： Fred T. Parker ,  Palle M. Hansen

发明人： Fred T. Parker ,  Palle M. Hansen

IPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2/97

CPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2/97 ,  A61F2002/9517

摘要： A stent introducer apparatus comprises a sheath for surrounding a stent member, with the sheath having a longitudinal slit extending from one end along at least a substantial part of the length thereof, and a sheath withdrawal device comprising a reel for winding up the sheath. A second sheath may surround the slit portion of the sheath. An intermediate guide member can smooth the withdrawal procedure and flatten the sheath before it is wound on the reel. The intermediate guide member may include at least one of a second reel or a slot-defining member. The reel may be operated by means of a gear system. A method of deploying a stent member is also provided.

摘要翻译： 支架引入装置包括用于围绕支架构件的护套，护套具有沿其长度的至少大部分的一端延伸的纵向狭缝，以及包括用于卷绕护套的卷轴的护套取出装置。 第二护套可以围绕护套的狭缝部分。 中间引导构件可以使护套平滑并且在将其卷绕在卷轴之前使其平坦化。 中间引导构件可以包括第二卷轴或槽限定构件中的至少一个。 卷轴可以通过齿轮系统来操作。 还提供展开支架构件的方法。

公开(公告)号：US08968381B2

公开(公告)日：2015-03-03

申请号：US13264331

申请日：2010-04-12

申请人： Fred T. Parker ,  Palle M. Hansen

发明人： Fred T. Parker ,  Palle M. Hansen

IPC分类号： A61F2/06 ,  A61L29/08 ,  A61F2/95 ,  A61F2/966 ,  A61F2/97

CPC分类号： A61F2/97 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2250/0039 ,  A61L29/085

摘要： A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.

摘要翻译： 提供了支架部署系统，手柄和装载医疗装置的方法。 该系统包括具有延伸穿过外导管的端部的内衬套和设置在外导管内的内导管的外导管。 内衬被倒置并连接到内导管上。 外导管和内导管之间的相对运动可促使内衬从医疗装置剥离。 手柄设置在外导管的近端处，并且可以包括被配置为切割管状构件的壁的分流器。 手柄还可以包括可连接到管状构件的可旋转机构。 可旋转机构的旋转将管状构件的一部分缩回到手柄中并围绕可旋转机构缠绕切片部分。

公开(公告)号：US08821510B2

公开(公告)日：2014-09-02

申请号：US12643312

申请日：2009-12-21

申请人： Fred T. Parker

发明人： Fred T. Parker

IPC分类号： A61F11/00 ,  A61F2/966 ,  A61L29/08 ,  A61F2/97 ,  A61F2/95

CPC分类号： A61L29/085 ,  A61F2/95 ,  A61F2/966 ,  A61F2/97 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2250/0039

摘要： A medical device including a tube having a coil fitted around at least a part of an inner liner, such as PTFE, and a braid extending over at least part of the coil. A polymeric layer is positioned over the braid to adhere to the inner liner. A portion of the coil advantageously comprises a polymer, such as PEEK, while the coil may also have a metal portion. The polymer coil may extend along at least at the proximal region of the tube, and the metal coil may extend along at least at the distal region of the tube. A polymer coil, a metal coil or any combination thereof can extend along the intermediate region of the tube. The polymer coil can be configured so that the tube is longitudinally splittable with a cutting instrument.

摘要翻译： 一种医疗装置，包括具有装配在诸如PTFE的内衬的至少一部分的线圈的管和在所述线圈的至少一部分上延伸的编织物的管。 聚合物层位于编织物上方以粘附到内衬。 线圈的一部分有利地包括聚合物，例如PEEK，而线圈也可以具有金属部分。 聚合物线圈可以至少在管的近端区域延伸，并且金属线圈可以至少在管的远端区域延伸。 聚合物线圈，金属线圈或其任何组合可以沿着管的中间区域延伸。 聚合物线圈可以被配置成使得管可以用切割器纵向分开。