公开(公告)号：US20120060445A1

公开(公告)日：2012-03-15

申请号：US12879611

申请日：2010-09-10

申请人： Chris Graham ,  Thaddeus Pesce ,  David Bell ,  Michael Abaskhroun ,  Mukesh Kasargode ,  Tak Man Lee ,  Galo Cadena

发明人： Chris Graham ,  Thaddeus Pesce ,  David Bell ,  Michael Abaskhroun ,  Mukesh Kasargode ,  Tak Man Lee ,  Galo Cadena

IPC分类号： B65B55/02 ,  B65B55/00

CPC分类号： B67C3/045 ,  A23L2/02 ,  A23L2/46 ,  A23L3/001 ,  A23L3/04 ,  A23L3/06 ,  B65B55/06 ,  B65B55/14

摘要： A method and an apparatus for hot-fill or cold fill sterilization of a container containing both a liquid and solid inclusions. The method and apparatus each prevent the inclusions from agglomerating in any area of the container, such as the container closure, thus allowing the liquid to contact the interior surfaces of the container for a time sufficient to achieve sterilization of the entire container. The filled container is subjected to an inversion sequence typically including alternating between inverting the container to an angle of about 60 degrees from vertical and an angle of about 140 degrees from vertical, over a time period of at least 30 seconds. The apparatus includes a means for conveying containers, configured to subject the containers to a series of angles as the containers are conveyed, as well as an enclosure for preventing the containers from falling off of the conveying means.

摘要翻译： 一种用于对容纳液体和固体夹杂物的容器进行热灌装或冷灌灭菌的方法和装置。 所述方法和装置均可防止夹杂物在容器的任何区域诸如容器封闭物之间聚集，从而允许液体接触容器的内表面足以实现整个容器的灭菌。 填充的容器经受反转序列，通常包括在至少30秒的时间段内将容器翻转至与垂直方向成大约60度的角度和大约140度的垂直角度的交替。 该装置包括用于输送容器的装置，其被构造成在容器被输送时使容器处于一系列角度，以及用于防止容器从输送装置脱落的外壳。

公开(公告)号：US20110104114A1

公开(公告)日：2011-05-05

申请号：US12999076

申请日：2009-06-26

申请人： Gord Adamson ,  David Bell ,  Steven Brookes

发明人： Gord Adamson ,  David Bell ,  Steven Brookes

IPC分类号： A61K38/17 ,  A61K38/19 ,  A61K38/21 ,  A61K39/44 ,  A61K38/44 ,  A61K38/45 ,  A61K38/50 ,  A61K38/28 ,  A61K38/37 ,  C07K14/555 ,  C07K17/10 ,  C07K17/12 ,  A61P7/00 ,  A61P35/00 ,  A61P3/10 ,  A61P1/04 ,  A61P15/00 ,  A61P37/02 ,  A61P31/00 ,  C12N9/96

CPC分类号： A61K47/4823 ,  A61K38/166 ,  A61K38/193 ,  A61K38/212 ,  A61K38/28 ,  A61K38/37 ,  A61K38/385 ,  A61K38/44 ,  A61K38/48 ,  A61K38/50 ,  A61K38/57 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/61 ,  A61K49/0017 ,  C07K16/2896 ,  C12Y107/03003 ,  C12Y305/01001

摘要： A method of preparing an oxidised polysaccharide-protein conjugate by oxidising a polysaccharide with an oxidising agent to form an oxidised polysaccharide and combining such oxidized polysaccharide with a protein. The oxidised polysaccharide is reacted with a protein to form a composition comprising a conjugate wherein the oxidised polysaccharide and the protein are conjugated via one or more imine bonds and wherein the oxidised polysaccharide comprises essentially no alpha-hydroxy aldehyde units. The conjugate may be used to provide sustained or latent activity of the protein.

摘要翻译： 一种通过用氧化剂氧化多糖以形成氧化的多糖并将这种氧化的多糖与蛋白质组合来制备氧化的多糖 - 蛋白质结合物的方法。 氧化的多糖与蛋白质反应以形成包含缀合物的组合物，其中氧化的多糖和蛋白质通过一个或多个亚胺键共轭，并且其中氧化的多糖基本上不含α-羟基醛单元。 缀合物可用于提供蛋白质的持续或潜在活性。

公开(公告)号：US20080015482A1

公开(公告)日：2008-01-17

申请号：US11485910

申请日：2006-07-13

申请人： David S. Utterberg ,  William J. Schnell ,  David Bell

发明人： David S. Utterberg ,  William J. Schnell ,  David Bell

IPC分类号： A61F13/00

CPC分类号： A61B17/0057 ,  A61B2017/00641

摘要： A soft hemostasis pad of elastomeric material having a hardness of no more than about 50 Shore 00 and an upper surface of raised profile, such as a dome. The pad may be connected by a hinge with another, generally flat-bottom pad of similar elastomeric material and hardness of no more than about 50 Shore 00. The pad may rest on the skin and be penetrated by a needle or other cannula. The pad with the raised profile may then be placed over on top of the needle, for improved hemostasis and sealing when the cannula is removed and before, facilitated by the application of gentle pressure, such as by tape that holds the pads in place.

摘要翻译： 弹性体材料的软止血垫具有不超过约50肖氏00的硬度和凸起轮廓的上表面，例如圆顶。 垫可以通过铰链与具有类似弹性体材料和不超过约50肖氏00的硬度的另一个大体上平底的垫连接。垫可以搁置在皮肤上并被针或其它套管穿透。 然后可以将具有凸起轮廓的垫放置在针的顶部上，以便在套管被移除之后并且之前通过施加温和的压力（例如通过将垫保持在适当位置的带）来促进止血和密封。

公开(公告)号：US20070179422A1

公开(公告)日：2007-08-02

申请号：US11270080

申请日：2005-11-09

申请人： William Schnell ,  David Bell ,  Karen Wilson ,  David Utterberg

发明人： William Schnell ,  David Bell ,  Karen Wilson ,  David Utterberg

IPC分类号： A61M37/00

CPC分类号： A61M1/3641 ,  A61M1/16 ,  A61M1/3627 ,  A61M1/3639 ,  A61M1/3655 ,  A61M39/00 ,  F16L29/005 ,  Y10T137/85978

摘要： A tubular medical fluid flow set comprises a pressure sensing chamber connected in flow-through relation to fluid flow tubing of the set. The pressure sensing chamber defines a movable, flexible, impermeable diaphragm dividing the chamber into two separate compartments. The fluid flow tubing communicates with one of the compartments and is isolated from the other of the compartments. A port is carried on the chamber, the port having a seal therein, and communicating with the other of the compartments. Thus, the other of the compartments is hermetically sealed until the port is opened for connection with a pressure measuring device, to keep the flexible diaphragm in a desired, initial position prior to opening of the seal.

摘要翻译： 管状医疗流体流动装置包括与组件的流体流管连通的压力感测室。 压力传感室限定了一个可移动的，柔性的，不可渗透的隔膜，将隔室分隔成两个独立的隔间。 流体流动管道与隔室中的一个连通，并且与隔室中的另一个隔离。 端口被承载在腔室上，该端口在其中具有密封，并且与另一个隔间连通。 因此，隔室中的另一个被气密地密封，直到端口打开以与压力测量装置连接，以便在打开密封件之前将柔性隔膜保持在期望的初始位置。

公开(公告)号：US20060259665A1

公开(公告)日：2006-11-16

申请号：US11128597

申请日：2005-05-13

申请人： Sanjive Agarwala ,  Kyle Castille ,  Quang An ,  David Bell ,  Natarajan Seshan

发明人： Sanjive Agarwala ,  Kyle Castille ,  Quang An ,  David Bell ,  Natarajan Seshan

IPC分类号： G06F13/38

CPC分类号： G06F13/28

摘要： The configurable multiple write-enhanced EDMA of this invention processes multiple priority channels and utilizes as much write data bus as practical. A write queue stores write requests with their corresponding data width and priority. A dispatch circuit dispatches a highest priority maximum data width write request if that is the highest priority stored write request or if the prior dispatch was not a maximum data width write request. The dispatch circuit dispatches two write requests if their total data width is less than or equal to the maximum data width and they both have a priority higher than the highest priority maximum data width write request.

摘要翻译： 本发明的可配置多写增强型EDMA处理多个优先级信道并且尽可能多地使用写入数据总线。 写队列存储具有相应数据宽度和优先级的写请求。 调度电路调度最高优先级的最大数据宽度写请求，如果这是最高优先级存储的写请求，或者先前的调度不是最大数据宽度写请求。 如果它们的总数据宽度小于或等于最大数据宽度并且它们都具有高于最高优先级最大数据宽度写入请求的优先级，则调度电路调度两个写入请求。

公开(公告)号：US20060085823A1

公开(公告)日：2006-04-20

申请号：US10529665

申请日：2003-09-15

申请人： David Bell ,  Steffan Reymann ,  Liesbeth Scholten

发明人： David Bell ,  Steffan Reymann ,  Liesbeth Scholten

IPC分类号： H04N7/18 ,  H04N7/173

CPC分类号： H04N21/44029 ,  H04N7/147 ,  H04N7/15 ,  H04N7/17318 ,  H04N21/2381 ,  H04N21/25833 ,  H04N21/4126 ,  H04N21/41407 ,  H04N21/43637 ,  H04N21/4516 ,  H04N21/454 ,  H04N21/4788 ,  H04N21/6131 ,  H04N21/6181 ,  H04N21/6587

摘要： A method of outputting multimedia content such as a video clip on a plurality of user devices (11, 12, 13) allows users of their devices to view the video clip in substantially time synchronised manner. Devices (10,11,12) communicate with each other to exchange control signals over a telecommunications network via communications links (13,14,15). The video clip is provided to user devices in advance of viewing so that during subsequent viewing only small control instructions denoting ‘play’, ‘stop’, ‘pause’ and the like need to be communicated between devices, where such small instructions suffer less from bandwidth constraints and latency of the communications network.

摘要翻译： 在多个用户设备（11,12,13）上输出诸如视频剪辑的多媒体内容的方法允许其设备的用户以基本上时间同步的方式来观看视频剪辑。 设备（10,11,12）彼此通信以经由通信链路（13,14,15）在电信网络上交换控制信号。 视频剪辑在观看之前被提供给用户设备，使得在随后的观看期间，只需要表示“播放”，“停止”，“暂停”等的小型控制指令在设备之间进行通信， 带宽约束和通信网络的延迟。

公开(公告)号：US20060079823A1

公开(公告)日：2006-04-13

申请号：US11218220

申请日：2005-09-01

申请人： David Utterberg ,  William Schnell ,  David Bell

发明人： David Utterberg ,  William Schnell ,  David Bell

IPC分类号： A61F13/00

CPC分类号： A61F13/0246 ,  A61F13/0243 ,  A61F2013/00417 ,  A61F2013/00468

摘要： A pad of elastomeric material having a softness of no more than about durometer 50 Shore 00. The pad may carry adhesive and/or a housing for adhering the pad to a surface, either directly or indirectly through an envelope which surrounds the pad and carries the adhesive. Such a pad exhibits hemostatic and leak prevention properties against needle puncture holes in the skin or the wall of a hollow medical device. Particularly, hemostasis may be prevented with low pressure application of the pad to the skin. The pad may be previously applied to the skin of the patient or a wall of a medical device such as tubing or a solution bag, and the needle may then penetrate both the pad and the skin or medical device wall, to make a resealable puncture with leakage reduction and hemostasis when the needle is withdrawn.

公开(公告)号：US07025744B2

公开(公告)日：2006-04-11

申请号：US10264863

申请日：2002-10-04

申请人： David S. Utterberg ,  William J. Schnell ,  David Bell

发明人： David S. Utterberg ,  William J. Schnell ,  David Bell

IPC分类号： A61M37/00 ,  A61M5/00 ,  A61M5/14

CPC分类号： A61M39/045 ,  A61M39/02 ,  A61M39/26

摘要： A medical device has an interior for containment of fluids; an opening into the interior, an elastomeric wall comprising a fixedly placed, flexible barrier across the opening; and a retention wall positioned adjacent to a peripheral portion of the elastomeric wall. The retention wall defines a central opening and has a generally rigid retention zone surrounding the central opening, to engage and retain a connector tube which is advanced into the central opening to displace the elastomeric wall and to open a flow aperture through the elastomeric wall, for flow through the wall and connector tube. One of the retention zone and connector tube are made of a material of sufficient hardness that material of the other engaging member is deformed by engagement therewith, which increases the strength of retention between the retention wall and the connector tube.

摘要翻译： 医疗装置具有用于容纳流体的内部; 通向内部的开口，弹性体壁，其包括穿过开口的固定放置的柔性屏障; 以及邻近弹性体壁的周边部分定位的保持壁。 保持壁限定中心开口并且具有围绕中心开口的大致刚性的保持区域，以接合并保持连接管，该连接器管进入中心开口以移动弹性体壁并打开穿过弹性体壁的流动孔，以便 流过墙壁和连接管。 保持区和连接管中的一个由足够硬度的材料制成，另一个接合构件的材料通过与其接合而变形，这增加了保持壁和连接管之间的保持强度。

公开(公告)号：US20060047646A1

公开(公告)日：2006-03-02

申请号：US10943652

申请日：2004-09-01

申请人： David Maluf ,  David Bell ,  Mohana Gurram ,  Yuri Gawdiak

发明人： David Maluf ,  David Bell ,  Mohana Gurram ,  Yuri Gawdiak

IPC分类号： G06F17/30 ,  G06F7/00

CPC分类号： G06F16/8358

摘要： Method and system for querying a collection of unstructured and semi-structured documents in a specified database to identify presence of, and provide context and/or content for, keywords and/or keyphrases. The documents are analyzed and assigned a node structure, including an ordered sequence of mutually exclusive node segments or strings. Each node has an associated set of at least four, five or six attributes with node information and can represent a format marker or text, with the last node in any node segment usually being a text node. A keyword (or keyphrase) query is specified, the query is converted to a statement that is recognized and respondeed to by the specified database, and the last node in each node segment is searched for a match with the keyword. When a match is found at a query node, or at a node determined with reference to a query node, the system displays the context and/or the content of the query node.

摘要翻译： 用于在指定数据库中查询非结构化和半结构化文档集合以识别关键字和/或关键短语的存在以及为关键字和/或关键短语提供上下文和/或内容的方法和系统。 对文档进行分析并分配一个节点结构，包括互斥节点段或字符串的有序序列。 每个节点具有至少四个，五个或六个具有节点信息的属性的关联集合，并且可以表示格式标记或文本，其中任何节点段中的最后一个节点通常是文本节点。 指定了关键字（或关键短语）查询，将查询转换为指定数据库识别和响应的语句，并搜索每个节点段中的最后一个节点与关键字的匹配。 当在查询节点或在参考查询节点确定的节点上找到匹配时，系统显示查询节点的上下文和/或内容。

公开(公告)号：US20050240688A1

公开(公告)日：2005-10-27

申请号：US11115014

申请日：2005-04-25

申请人： Filip Moerman ,  Pierre Bertrand ,  David Bell

发明人： Filip Moerman ,  Pierre Bertrand ,  David Bell

IPC分类号： G06F13/28

CPC分类号： G06F13/28

摘要： A method comprising generating a transfer configuration descriptor (“TCD”), said TCD comprising information pertaining to data to be transferred. The method further comprises dynamically configuring a direct memory access (“DMA”) channel based on said TCD without using a CPU and transferring a group of data blocks by way of said DMA channel.

摘要翻译： 一种方法，包括生成传送配置描述符（“TCD”），所述TCD包括与要传送的数据有关的信息。 该方法还包括基于所述TCD动态配置直接存储器访问（“DMA”）信道，而不使用CPU并通过所述DMA通道传送一组数据块。