公开(公告)号：US09988170B2

公开(公告)日：2018-06-05

申请号：US15329328

申请日：2015-09-18

Applicant: Dai Nippon Printing Co., Ltd.

Inventor： Yoshinori Sato ,  Hirotaka Tsuchiya

IPC: A61L2/14 ,  A61L2/00 ,  B65B55/10 ,  A61L2/22 ,  A61L2/20 ,  B65B39/00 ,  B65B3/04 ,  B65B7/28

CPC classification number: B65B55/10 ,  A61L2/14 ,  A61L2/186 ,  A61L2/208 ,  A61L2/22 ,  A61L2202/23 ,  B65B3/04 ,  B65B7/2835 ,  B65B31/025 ,  B65B39/00 ,  B65B55/06 ,  B65B55/08

Abstract: A sterilization process is performed on a preform or container made of resin after a corona discharge treatment is performed on an inner surface of the preform or container, the corona discharge treatment including applying a voltage produced in a corona discharge to an electrode that passes through an opening part of the preform or container, an insertion step of inserting the electrode to which the voltage is applied into the preform or container through the opening part, and a bottom part treatment step of treating an inner surface of a bottom part of the preform or container by bringing the electrode close to the bottom part until the corona discharge from the electrode changes discharge mode, and the sterilization process including a hydrogen peroxide supplying step of blasting a mist or gas of hydrogen peroxide solution or a mixture thereof to the preform or container.

公开(公告)号：US20180036310A1

公开(公告)日：2018-02-08

申请号：US15550638

申请日：2016-02-12

Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.

Inventor： Samarth KUMAR ,  Prashant KANE ,  Subhas Balaram BHOWMICK ,  Kirti GANORKAR ,  Nisarg Bipinchandra MISTRY ,  Ramaji Karshanbhai VARU

IPC: A61K31/519 ,  A61K41/00 ,  A61K9/08 ,  B65B55/06 ,  A61J1/10 ,  B65B3/00 ,  B65B7/02 ,  A61K9/00 ,  A61K47/02

CPC classification number: A61K31/519 ,  A61J1/10 ,  A61K9/0019 ,  A61K9/08 ,  A61K41/0009 ,  A61K47/02 ,  A61M5/14 ,  B65B3/003 ,  B65B7/02 ,  B65B55/06

Abstract: The present invention relates to an intravenous infusion dosage form of pemetrexed or its pharmaceutically acceptable salt, having long term stability.

公开(公告)号：US20170290358A1

公开(公告)日：2017-10-12

申请号：US15472150

申请日：2017-03-28

Applicant: John Bean Technologies Corporation

Inventor： Zhijun Weng ,  Jeffrey A. Dahl ,  Douglas Neil Woodruff ,  Kevin Andrew Carlson

IPC: A23L3/02 ,  A23L3/00

CPC classification number: A23L3/022 ,  A23L3/003 ,  A23L3/005 ,  A23L3/02 ,  A23L3/18 ,  B65B3/04 ,  B65B55/027 ,  B65B55/06 ,  B65B55/14 ,  B67C3/14 ,  B67C7/00 ,  B67C2003/2694

Abstract: An automated, unmanned continuous system (200) for packaging flowable food products at elevated temperatures and pressures includes an upstream thermal processing station (202) to heat the food products and direct the heated food products to a pressurized unmanned filling station (204), whereat containers (242) are filled with the heated food products within a pressurized housing (232), and then transported to a pressurized and unmanned sealing station (206) where the containers are sealed with a lid or cover (283) within a pressurized housing (282). Thereafter, the filled and sealed containers (242) are routed from the pressurized housing (282) through a pressurized transfer tube or passageway (208) for further processing at a downstream thermal processing station (210).

公开(公告)号：US20170203868A1

公开(公告)日：2017-07-20

申请号：US15410740

申请日：2017-01-19

Applicant: Dr. Py Institute, LLC

Inventor： Daniel Py ,  Julian V. Chan

IPC: B65B55/06 ,  B65B61/18 ,  B65B3/02 ,  B65B3/04 ,  B29C69/02 ,  A61J1/10 ,  B65D75/54 ,  A61J1/14 ,  B65B7/02 ,  B65B51/02 ,  B65B61/06

CPC classification number: B65B55/06 ,  A61J1/10 ,  A61J1/1475 ,  B29C69/00 ,  B29C69/001 ,  B29C69/02 ,  B29K2021/003 ,  B29L2031/7128 ,  B31B70/844 ,  B65B3/022 ,  B65B3/04 ,  B65B7/02 ,  B65B51/02 ,  B65B61/06 ,  B65B61/186 ,  B65D75/54 ,  B65D75/5883 ,  B65D81/3266 ,  B65D2575/586

Abstract: A sealed, empty pouch, wherein the interior of the pouch is particle and pyrogen free, is made by (i) molding a tubular film including an inner surface and an outer surface, and blowing or otherwise directing micro-filtered air and/or other gas through the tubular film during molding; (ii) flattening the molded tubular film; (iii) sealing the flattened tubular film at spaced locations, cutting the sealed film at the spaced locations, and forming a plurality of empty pouches; (iv) over-molding a fitment to the outer surface of each of a plurality of empty pouches and forming a fluid-tight seal between the fitment and the interior of the pouch; and (v) preventing the collection of particles on the inner surface of each pouch, and the exposure of each such inner surface to an ambient atmosphere throughout steps (i) through (iv).

公开(公告)号：US09505513B2

公开(公告)日：2016-11-29

申请号：US12675010

申请日：2008-09-23

Applicant: Michael Wolters ,  Thomas Dintelmann

Inventor： Michael Wolters ,  Thomas Dintelmann

IPC: A61L2/20 ,  B65B55/06 ,  A23L3/00 ,  A23L3/10 ,  A23L3/14 ,  B32B27/10 ,  D21H17/00 ,  D21H19/10 ,  D21H21/16 ,  D21H27/00 ,  D21H27/30 ,  A61L2/04

CPC classification number: B65B55/06 ,  A23L3/001 ,  A23L3/10 ,  A23L3/14 ,  A61L2/04 ,  B32B27/10 ,  B32B2307/412 ,  B32B2307/72 ,  B32B2307/73 ,  B32B2439/00 ,  D21H17/00 ,  D21H19/10 ,  D21H21/16 ,  D21H27/00 ,  D21H27/30 ,  Y10T428/1303

Abstract: A device for sterilizing cuboid-shaped cardboard/plastic combipacks in an autoclave, wherein the packs consisting of product and packing are subjected to heat treatment at a certain temperature over a certain period of time, wherein the product consists of a liquid and chunky portions, and wherein mechanisms are provided inside the autoclave to drive the packs rotationally about a rotational spindle, and a cuboid-shaped cardboard/plastic combipack for use in such a device.A plurality of packs, are arranged closely adjacent to one another in parallel rows, to be arranged on support floors and for a plurality of support floors loaded with packs to be arranged one above the other and fixed in their mutual positions. The cardboard for the pack used therewith is made water-repellent by means of glue to reduce the intake of water.

Abstract translation: 多个包装被布置成彼此紧密相邻的平行排列，以布置在支撑楼层上，并且被布置在多个支撑地板上，所述多个支撑楼层被装载成一个在另一个之上并被固定在相互位置上的包装。 用于其中的包装的纸板通过胶水被防水，以减少水的摄取。

公开(公告)号：US20160107918A1

公开(公告)日：2016-04-21

申请号：US14893783

申请日：2014-05-27

Applicant: DALWICK CONTINENTAL CORP

Inventor： José de Jesús DELGADO CARRANZA

IPC: C03B23/04 ,  B65B23/22 ,  C03B32/00 ,  B65B55/06 ,  C03B21/02 ,  A61J1/14 ,  B65B55/14

CPC classification number: C03B23/04 ,  A61J1/065 ,  A61J1/1468 ,  B65B23/22 ,  B65B55/06 ,  B65B55/14 ,  C03B21/02 ,  C03B23/09 ,  C03B23/097 ,  C03B23/11 ,  C03B32/00

Abstract: The present invention relates to a method for manufacturing glass containers for pharmaceutical use. This method allows obtaining containers with a low degree of alkalinity. In some preferred embodiments the process allows the manufacture of sterile containers and substantially free of particles ready to be used by the pharmaceutical industry.

Abstract translation: 本发明涉及制造药物用玻璃容器的方法。 该方法允许获得低碱度的容器。 在一些优选的实施方案中，该方法允许制造无菌容器并且基本上不含准备由制药工业使用的颗粒。

公开(公告)号：US09301345B2

公开(公告)日：2016-03-29

申请号：US13799991

申请日：2013-03-13

Applicant: Microwave Materials Technologies, Inc.

Inventor： Harold Dail Kimrey, Jr.

IPC: H05B6/70 ,  H05B6/68 ,  H05B6/80 ,  H05B6/78 ,  H01L21/67

CPC classification number: H05B6/78 ,  A23L3/01 ,  A23L3/02 ,  A23V2002/00 ,  A61B90/70 ,  A61L2/04 ,  A61L2/12 ,  A61L2202/21 ,  A61L2202/24 ,  A61L2202/26 ,  B65B55/06 ,  H01L21/67201 ,  H05B6/68 ,  H05B6/70 ,  H05B6/782 ,  H05B6/80

Abstract: A method for heating a plurality of articles according to a prescribed heating profile is provided. The method includes heating a first test article in a small-scale microwave heating system and, based on the value of one or more parameters determined during this small-scale heating, determining a prescribed heating profile for the test article. Suitable parameters can include for example, net power discharged, sequential microwave distribution, average temperature and flow rate of the fluid in the heating chamber, and residence time. The heating profile can then be used to control a commercial-scale microwave heating system used to heat a plurality of similar articles.

Abstract translation: 提供了一种根据规定的加热曲线加热多个物品的方法。 该方法包括加热小型微波加热系统中的第一测试物品，并且基于在该小型加热期间确定的一个或多个参数的值，确定测试物品的规定加热曲线。 合适的参数可以包括例如净功率放电，连续的微波分布，加热室中的流体的平均温度和流速以及停留时间。 然后可以使用加热曲线来控制用于加热多个类似物品的商业规模的微波加热系统。

公开(公告)号：US09102097B2

公开(公告)日：2015-08-11

申请号：US13396053

申请日：2012-02-14

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B3/00 ,  B65B7/28 ,  B29C67/00 ,  B29C45/00 ,  B29C45/17 ,  B29C65/00 ,  B65B3/02 ,  B65B55/06 ,  B29L31/56 ,  B29C45/42

CPC classification number: B29C67/004 ,  B29C45/006 ,  B29C45/1701 ,  B29C45/42 ,  B29C65/16 ,  B29C65/1616 ,  B29C66/001 ,  B29C66/0018 ,  B29C66/71 ,  B29C66/91212 ,  B29C66/91216 ,  B29C66/91221 ,  B29C66/91411 ,  B29C66/91431 ,  B29C66/961 ,  B29C2791/005 ,  B29L2031/565 ,  B65B3/003 ,  B65B3/022 ,  B65B55/06 ,  B29C65/00 ,  B29K2023/38

Abstract: A stopper and container body are molded in the same molding machine. An assembly device, such as a pick and place robot, transfers the stopper from one mold cavity into the opening in the container body located within another mold cavity, or vice versa, to assemble the stopper and container body. Then, the assembled container body and stopper are removed from the molding machine and transported to a needle filling and laser resealing station for filling and laser resealing. A laminar flow source directs a substantially laminar flow of air or sterile gas over the mold surfaces, stoppers and container bodies, and assembly device, to prevent contamination during assembly.

Abstract translation: 塞子和容器主体在相同的成型机中成型。 诸如拾放机器人的组装装置将止动器从一个模腔转移到位于另一个模腔内的容器主体中的开口中，反之亦然，以组装止动器和容器主体。 然后，将组装的容器主体和止动件从成型机中取出并输送到针填充和激光重新密封站，用于填充和激光重新密封。 层流源将空气或无菌气体的基本层流引导到模具表面，塞子和容器主体以及组装装置上，以防止组装过程中的污染。

公开(公告)号：US09073655B2

公开(公告)日：2015-07-07

申请号：US13878688

申请日：2011-10-14

Applicant: Christian Bratsch

Inventor： Christian Bratsch

IPC: B65B7/28 ,  B65D51/18 ,  B65B55/06 ,  B65D17/00 ,  B65D51/00

CPC classification number: B65B55/06 ,  B65D17/4014 ,  B65D51/00

Abstract: A filled and reclosable pressure vessel, in which a body is filled with a fluid, closed with a lid element (10, 100) and subjected to a heat treatment, with a lid surface (11, 110), and a closure (14) made of plastics as a lid element (10, 100), and at least one seal (16) arranged on the closure (14), the lid element (10, 100) being arranged in such a way that the closure (14) faces the interior of the sealed pressure vessel, wherein the lid surface (11, 110) and the closure (14) are arranged in such a way that the lid surface (11, 110) has a first distance (a1) from a first reference plane (E1) which substantially extends through the at least one sealing surface (16a) on the first surface (111) of the lid surface (11, 110), and the closure (14) extends at a second distance from a second reference plane which extends through the at least one seal (16), with the first distance (a1) being chosen to be larger than the second distance.

Abstract translation: 一种填充且可重新闭合的压力容器，其中用盖子元件（10,100）封闭主体并填充有流体，并用盖表面（11,110）和封闭件（14）进行热处理， 由塑料制成的盖元件（10,100）和至少一个密封件（16）布置在所述封闭件（14）上，所述盖元件（10,100）以使得所述封闭件（14）面对 所述密封压力容器的内部，其中所述盖表面（11,110）和所述封闭件（14）以使得所述盖表面（11,110）具有与第一参考平面（11,110）的第一距离（a1） （E1），其基本上延伸穿过所述盖表面（11,110）的第一表面（111）上的所述至少一个密封表面（16a），并且所述封闭件（14）以第二参考平面 延伸通过至少一个密封件（16），其中第一距离（a1）被选择为大于第二距离。

公开(公告)号：US20140311095A1

公开(公告)日：2014-10-23

申请号：US14354061

申请日：2012-10-23

Applicant: SAI NIPPO PRINTING CO., LTD.

Inventor： Atsushi Hayakawa ,  Hideo Hidaka

IPC: B65B55/10 ,  B65B7/28 ,  B65B3/02

CPC classification number: B65B55/10 ,  A61L2/186 ,  A61L2/208 ,  A61L2/22 ,  A61L2202/23 ,  B65B3/022 ,  B65B7/28 ,  B65B55/06 ,  B65B55/24 ,  B67C7/0073 ,  B67C2003/227

Abstract: A drink package is manufactured by a method including the steps of: blasting hydrogen peroxide mist (M) or gas (G) into a container (2) in an erected attitude through a mouth portion (2a); activating the hydrogen peroxide in the container (2) in an inverted attitude by blasting heated aseptic air (N) through the mouth portion (2a) thereof directed downward, and simultaneously, removing foreign substance (P) from the inside of the container (2) by replacing air in the container (2) with the aseptic air (N); filling the container (2) in the erected attitude with drink (a) through the mouth portion (2a) directed upward; and closing the mouth portion (2a) of the container (2) by applying a lid (3) to the mouth portion (2a) of the container (2).

Abstract translation: 通过包括以下步骤的方法制造饮料包装：通过口部（2a）将过氧化氢雾（M）或气体（G）以竖立姿态喷射到容器（2）中; 通过喷射加热的无菌空气（N）通过其向下的嘴部（2a），以倒立的姿态激活容器（2）中的过氧化氢，同时从容器（2）的内部除去异物 ）通过用无菌空气（N）代替容器（2）中的空气; 以饮料（a）通过朝向上方的口部（2a）将所述容器（2）以竖立姿态填充; 以及通过向容器（2）的口部（2a）施加盖（3）来封闭容器（2）的口部（2a）。