公开(公告)号：US07709637B2

公开(公告)日：2010-05-04

申请号：US11548864

申请日：2006-10-12

申请人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D403/04 ,  C07D239/38

CPC分类号： C07D239/42 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/647 ,  A01N43/653 ,  A01N43/713 ,  A01N43/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04 ,  C07D473/06 ,  C07D487/04

摘要： 5-Phenylpyrimidines of the formula I, in which the substituents have the following meanings: R1 is a five- to ten-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle comprising one to four hetero atoms selected from the group consisting of O, N or S, which heterocycle can be substituted as defined in the description, R2 is hydrogen, halogen, cyano, alkyl, haloalkyl or alkoxy; R3, R4 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, R3 and R4 together with the nitrogen atom to which they are bonded may also form a five- or six-membered ring which can be interrupted by a hetero atom and have attached to it one or more substituents; R5, R6 are hydrogen, halogen, alkyl, haloalkyl or alkoxy; R7, R8 are hydrogen, halogen, alkyl or haloalkyl; R9 is hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, haloalkoxy or alkoxycarbonyl, Processes and intermediates for the preparation of these compounds, and their use for controlling harmful fungi.

摘要翻译： 式I的5-苯基嘧啶，其中取代基具有以下含义：R 1是5至10元饱和的，部分不饱和的或芳族的单环或双环杂环，其包含一至四个选自O ，N或S，该杂环可以如描述中所定义而被取代，R 2是氢，卤素，氰基，烷基，卤代烷基或烷氧基; R3，R4是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，R3和R4与它们所键合的氮原子一起也可以形成五元或六元环 其可以被杂原子中断并且与其连接一个或多个取代基; R5，R6是氢，卤素，烷基，卤代烷基或烷氧基; R 7，R 8为氢，卤素，烷基或卤代烷基; R9是氢，卤素，烷基，烷氧基，环烷氧基，卤代烷氧基或烷氧羰基。用于制备这些化合物的方法和中间体及其用于控制​​有害真菌的用途。

公开(公告)号：US07153860B2

公开(公告)日：2006-12-26

申请号：US10471532

申请日：2002-03-13

申请人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D239/42 ,  A01N43/54 ,  C07D239/47

CPC分类号： C07D239/42 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/647 ,  A01N43/653 ,  A01N43/713 ,  A01N43/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04 ,  C07D473/06 ,  C07D487/04

摘要： The invention relates to 5-phenylpyrimidine of formula (I) wherein the substituents have the following designations: R1 represents a five to ten-membered saturated, partially unsaturated or aromatic monocyclic or bicyclic heterocycle which contains between one and four heteroatoms from the group O, N or S, and which can be substituted as defined in the description; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3 and R4 represent hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl; together with the nitrogen atom to which they are bonded, R3 and R4 can also form a five or six-membered ring which can be split by a heteroatom and can carry at least one substituent; R5 and R6 represent hydrogen, halogen, alkyl, halogenalkyl or alkoxy; R1 and R8 represent hydrogen, halogen, alkyl or halogenalkyl; and R9 represents hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, halogenalkoxy or alkoxycarbonyl. The invention also relates to methods and intermediate products for producing said compounds and the use of the same for controlling pathogenic fungi

摘要翻译： 本发明涉及式（I）的5-苯基嘧啶，其中取代基具有以下指定：R 1表示5至10元饱和，部分不饱和或芳族单环或双环杂环，其含有一个 和来自O，N或S基团的四个杂原子，并且可以如说明书中定义的那样被取代; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3和R 4代表氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基; 与它们所键合的氮原子一起，R 3和R 4还可以形成五元或六元环，其可以被杂原子分解并且可以携带 至少一个取代基; R 5和R 6代表氢，卤素，烷基，卤代烷基或烷氧基; R 1和R 8代表氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，烷基，烷氧基，环烷氧基，卤代烷氧基或烷氧基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物及其用于控制​​致病真菌的用途

公开(公告)号：US20070191398A1

公开(公告)日：2007-08-16

申请号：US11579672

申请日：2005-04-27

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

IPC分类号： A01N43/90 ,  A01N43/40

CPC分类号： A01N43/90 ,  A01N2300/00

摘要： Fungicidal mixtures comprising, as active components, 1) the triazolopyrimidine derivative of the formula I and 2) the benzamide of the formula II in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compound I with the compound II and the use of the compound I with the compound II for preparing such mixtures, and also compositions comprising these mixtures.

摘要翻译： 作为活性组分的包含1）式I的三唑并嘧啶衍生物和2）协同有效量的式II的苯甲酰胺的杀真菌混合物，使用化合物I和化合物II的混合物控制有害真菌的方法和使用 的化合物II与用于制备这种混合物的化合物II，以及包含这些混合物的组合物。

公开(公告)号：US20080058352A1

公开(公告)日：2008-03-06

申请号：US10594268

申请日：2005-03-22

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

IPC分类号： A01N43/56 ,  A01N43/78 ,  A01N43/90

CPC分类号： A01N43/90 ,  A01N2300/00

摘要： Fungicidal mixtures comprising, as active components, 1) the triazolopyrimidine derivative of the formula I and 2) an anilide of the formula II  in which the variables are as defined below: Ar is phenyl or a five- or six-membered aromatic heterocycle which contains one to four heteroatoms selected from the group consisting of O, N and S, where the cycles are unsubstituted or may be substituted by one to three groups R1: R1 is halogen, alkyl or haloalkyl; R is phenyl, alkyl, haloalkyl, alkoxy, haloalkoxy; Q is hydrogen, alkyl, haloalkyl, alkoxy, haloalkoxy; in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compound I with the compound II and the use of the compound I with the compound II for preparing such mixtures, and also compositions comprising these mixtures.

摘要翻译： 作为活性组分的杀真菌混合物包括1）式I的三氮代嘧啶衍生物和2）式II的酰苯胺，其中变量如下所定义：Ar是苯基或五或六元芳族杂环，其含有 一至四个选自O，N和S的杂原子，其中循环是未取代的或可以被一至三个R 1取代：R 1是 卤素，烷基或卤代烷基; R是苯基，烷基，卤代烷基，烷氧基，卤代烷氧基; Q是氢，烷基，卤代烷基，烷氧基，卤代烷氧基; 协同有效量的方法，使用化合物I与化合物II的混合物来控制有害真菌，以及使用化合物I与化合物II制备这种混合物，以及包含这些混合物的组合物。

公开(公告)号：US20070197556A1

公开(公告)日：2007-08-23

申请号：US11579048

申请日：2005-05-11

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl ,  Markus Gewehr

IPC分类号： A01N43/76 ,  A01N43/64 ,  A01N43/26 ,  A01N43/90 ,  A01N43/78 ,  A01N43/50

CPC分类号： A01N43/90 ,  A01N43/78 ,  A01N43/56 ,  A01N43/32 ,  A01N43/08 ,  A01N2300/00

摘要： Fungicidal mixtures, comprising, as active components, 1) the triazolopyrimidine derivative of the formula I and 2) at least one biphenylamide of the formula II in which the variables are as defined below: A is oxathiinyl or 5-membered heteroaryl which contains one to four nitrogen atoms or one to three nitrogen atoms and/or one sulfur or oxygen atom, where A may be substituted according to the description; R1 is hydrogen, alkyl, alkylcarbonyl or a group A which is attached via carbonyl; Ra, Rb are halogen, cyano, alkyl, haloalkyl, alkoxycarbonyl, alkoxy, haloalkoxy, alkylthio, alkylcarbonyl, formyl, alkylene or alkenylene which links two adjacent carbon atoms; m is 0, 1, 2, 3, 4 or 5; n is 0, 1 or 2; in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compound I with compound II and the use of the compound I with compounds II for preparing such mixtures, and also compositions comprising these mixtures.

摘要翻译： 包含作为活性成分的杀真菌混合物，1）式I的三唑并嘧啶衍生物和2）至少一种式II的联苯酰胺，其中变量如下所定义：A是氧亚硫代基或5元杂芳基，其含有1至 四个氮原子或一至三个氮原子和/或一个硫或氧原子，其中A可以根据描述被取代; R 1是氢，烷基，烷基羰基或通过羰基连接的基团A; R 2是卤素，氰基，烷基，卤代烷基，烷氧基羰基，烷氧基，卤代烷氧基，烷硫基，烷基羰基，甲酰基，亚烷基或亚链烯基，其连接两个相邻的碳原子; m为0,1,2,3,4或5; n为0,1或2; 在协同有效量的情况下，使用化合物I与化合物II的混合物控制有害真菌的方法以及化合物I与化合物II用于制备此类混合物的用途，以及包含这些混合物的组合物。

公开(公告)号：US06552026B2

公开(公告)日：2003-04-22

申请号：US09735033

申请日：2000-12-12

申请人： Klaus Jüergen Pees ,  Jordi Tormo i Blasco ,  Hubert Sauter ,  Oliver Cullman ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegried Strathmann ,  Gisela Lorenz ,  Rheinhard Stierl

发明人： Klaus Jüergen Pees ,  Jordi Tormo i Blasco ,  Hubert Sauter ,  Oliver Cullman ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegried Strathmann ,  Gisela Lorenz ,  Rheinhard Stierl

IPC分类号： C07D48704

CPC分类号： C07D487/04

摘要： 6-Phenyl-Pyrazolopyrimidines of formula I wherein R1 is alkyl, alkenyl, alkynyl, alkadienyl or haloalkyl, cycloalkyl, bicycloalkyl, phenyl, naphthyl, or 5- or 6-membered heterocyclyl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or 5- or 6-membered heteroaryl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom,  where these radicals may be unsubstituted or substituted as defined in the specification, Y is oxygen, sulfur, NR2 or a single bond; wherein R2is defined in the specification; and R1 and R 2 together with the interjacent nitrogen atom may represent a 5- or 6-membered heterocyclic ring, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which may be substituted by one or more Rc radicals; m is 0 or an integer from 1 to 4; L each independently is halogen, nitro, alkyl, alkoxy, and X is halogen; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic fungi are described.

摘要翻译： 式I的6-苯基 - 吡唑并嘧啶，其中R1是具有1-4个氮原子或1-3个氮原子的烷基，烯基，炔基，链二烯基或卤代烷基，环烷基，双环烷基，苯基，萘基或5-或6-元杂环基， 硫或氧原子，或含有一至四个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元杂芳基，其中这些基团可以未被取代或如说明书中所定义取代，Y是氧 ，硫，NR 2或单键; 其中R2在说明书中定义; 并且R 1和R 2与中间的氮原子一起可以表示含有1-4个氮原子或1-3个氮原子和一个硫或氧原子的5或6元杂环，其可被一个或多个R c 基团; m为0或1至4的整数; L各自独立地为卤素，硝基，烷基，烷氧基和X为卤素;制备这些化合物的方法和中间体，包含它们的组合物及其用于防治植物病原真菌的用途。

公开(公告)号：US06730680B2

公开(公告)日：2004-05-04

申请号：US10314595

申请日：2002-12-10

申请人： Klaus Jüergen Pees ,  Jordi Tormo i Blasco ,  Hubert Sauter ,  Oliver Cullman ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegried Strathmann ,  Gisela Lorenz ,  Rheinhard Stierl

发明人： Klaus Jüergen Pees ,  Jordi Tormo i Blasco ,  Hubert Sauter ,  Oliver Cullman ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegried Strathmann ,  Gisela Lorenz ,  Rheinhard Stierl

IPC分类号： A01N4354

CPC分类号： C07D487/04

摘要： 6-Phenyl-Pyrazolopyrimidines of formula I wherein R1 is alkyl, alkenyl, alkynyl, alkadienyl or haloalkyl, cycloalkyl, bicycloalkyl, phenyl, naphthyl, or 5- or 6-membered heterocyclyl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or 5- or 6-membered heteroaryl, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom,  where these radicals may be unsubstituted or substituted as defined in the specification, Y is oxygen, sulfur, NR2 or a single bond; wherein R2 is defined in the specification; and R1 and R2 together with the interjacent nitrogen atom may represent a 5- or 6-membered heterocyclic ring, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which may be substituted by one or more Rc radicals; m is 0 or an integer from 1 to 4; L each independently is halogen, nitro, alkyl, alkoxy, and X is halogen; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic fungi are described.

摘要翻译： 式I的6-苯基 - 吡唑并嘧啶，其中R 1是含有1-4个氮原子或一至三个氮的烷基，烯基，炔基，链二烯基或卤代烷基，环烷基，二环烷基，苯基，萘基或5-或6-元杂环基 原子和一个硫或氧原子，或含有一至四个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元杂芳基，其中这些基团可以未被取代或如说明书中所定义的取代， Y是氧，硫，NR 2或单键; 其中R 2在说明书中定义; 和R 1和R 2与中间的氮原子一起可以表示含有1-4个氮原子或1-3个氮原子和一个硫或氧原子的5或6元杂环，其可被取代 由一个或多个R c基团取代; m为0或1至4的整数; L各自独立地为卤素，硝基，烷基，烷氧基和X为卤素;制备这些化合物的方法和中间体， 描述了用于控制植物病原真菌的用途。

公开(公告)号：US20080139387A1

公开(公告)日：2008-06-12

申请号：US10585981

申请日：2005-01-15

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC分类号： A01N25/34 ,  A01N43/84 ,  A01P3/00

CPC分类号： A01N43/90 ,  A01N43/84 ,  A01N2300/00

摘要： The invention relates to fungicidal mixtures for the control of fungal pests harmful to plants, comprising the active components 1) the triazolopyrimidine derivative of formula (1), and 2) tridemorph of formula (II), in which n=10, 11, 12 (60-70%) or 14, in a synergistically-effective amount, method for the control of fungal pests using mixtures of compound (I) with the compounds (II), the use of compound (I) with the compounds (II) for the production of such mixtures and means comprising said mixtures.

摘要翻译： 本发明涉及用于控制对植物有害的真菌害虫的杀真菌混合物，其包含活性组分1）式（1）的三唑并嘧啶衍生物和2）式（II）的三美丹，其中n = 10,11,12 （I）与化合物（II）的混合物，使用化合物（I）与化合物（II）的混合物来控制真菌害虫的方法（60-70％）或14， 用于生产这样的混合物和包含所述混合物的装置。

公开(公告)号：US20080139386A1

公开(公告)日：2008-06-12

申请号：US10585741

申请日：2005-01-13

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC分类号： A01N25/34 ,  A01N43/54 ,  A01P3/00

CPC分类号： A01N43/90 ,  A01N47/32 ,  A01N2300/00

摘要： Fungicidal mixtures for controlling harmful fungi, which mixtures comprise, as active components,1) the triazolopyrimidine derivative of the formula I and2) pencycuron of the formula II in a synergistically effective amount, methods for controlling rice pathogens using mixtures of the compound I with the compounds II and the use of the compound I with the compounds II for preparing such mixtures, and also compositions comprising these mixtures.

摘要翻译： 用于控制有害真菌的杀真菌混合物，其混合物包含作为活性组分的1）式I的三氮代嘧啶衍生物和2）协同有效量的式II的焦虑霉素，使用化合物I与 化合物II和化合物I与化合物II用于制备这种混合物的用途，以及包含这些混合物的组合物。

公开(公告)号：US20080064692A1

公开(公告)日：2008-03-13

申请号：US10585758

申请日：2005-01-14

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC分类号： A01N25/26 ,  A01N43/88 ,  A01N43/90 ,  A01P3/00

CPC分类号： A01N43/90 ,  A01N43/88 ,  A01N2300/00

摘要： Fungicidal mixtures comprising, as active components, 1) the triazolopyrimidine derivative of the formula I and 2) fluoxastrobin of the formula II in a synergistically effective amount, methods for controlling phytopathogenic harmful fungi using mixtures of the compound I with the compounds II and the use of the compound I and the compounds II for preparing such mixtures, and also compositions comprising these mixtures are described.

摘要翻译： 包含作为活性组分的1）式I的三氮代嘧啶衍生物和2）协同有效量的式II的氟草胺的防霉混合物，使用化合物I和化合物II的混合物控制植物病原性有害真菌的方法和使用 的化合物I和用于制备这种混合物的化合物II，以及包含这些混合物的组合物。