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公开(公告)号：US5721238A
公开(公告)日：1998-02-24
申请号：US584865
申请日：1996-01-11
申请人： Fred Robert Heiker , Ulrich Niewohner , Wolfgang Hartwig , Helmuth Schutz , Erwin Bischoff , Elisabeth Perzborn , Matthias Schramm
发明人： Fred Robert Heiker , Ulrich Niewohner , Wolfgang Hartwig , Helmuth Schutz , Erwin Bischoff , Elisabeth Perzborn , Matthias Schramm
IPC分类号： A61K31/505 , A61K31/517 , A61K31/535 , A61K31/655 , A61P7/02 , A61P9/06 , A61P9/08 , A61P9/10 , A61P13/08 , A61P29/00 , A61P43/00 , C07D239/91 , C07D405/04 , C07D413/12 , C07D413/14 , C07D239/80
CPC分类号： C07D405/04 , C07D239/91
摘要： 2,8-Disubstituted quinazolinones are prepared by first subjecting the quinazolinone basic skeleton to condensation by customary reactions and then introducing the desired substituents into the 8-position. The compounds are suitable as active compounds in medicaments, in particular for the treatment of inflammations, thromboembolic diseases and cardiovascular diseases.
摘要翻译： 通过首先使喹唑啉酮碱性骨架通过常规反应冷凝，然后将所需的取代基引入8-位来制备2,8-二取代喹唑啉酮。 该化合物适合作为药物中的活性化合物，特别是用于治疗炎症，血栓栓塞性疾病和心血管疾病。
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公开(公告)号：US5272161A
公开(公告)日：1993-12-21
申请号：US942550
申请日：1992-09-09
申请人： Ulrich Niewohner , Siegfried Goldmann , Ulrich Muller , Andreas Knorr , Elisabeth Perzborn , Matthias Schramm , Bernhard Beckermann
发明人： Ulrich Niewohner , Siegfried Goldmann , Ulrich Muller , Andreas Knorr , Elisabeth Perzborn , Matthias Schramm , Bernhard Beckermann
IPC分类号： A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/455 , A61K31/505 , A61P7/02 , A61P9/00 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14
CPC分类号： C07D401/12 , C07D401/14
摘要： Indolesulphonamide-substituted dihydropyridines can be prepared by reaction of dihydropyridinecarboxylic acids with hydroxy-substituted indolesulphonamides, or by reaction of amino- or hydroxy-substituted dihydropyridines with indolesulphonamidecarboxylic acids. The indolesulphonamide-substituted dihydropyridines can be employed as active substances in medicaments for the treatment of cardiac, circulatory and thromboedabolic disorders.
摘要翻译： 吲哚磺酰胺取代的二氢吡啶可以通过二氢吡啶羧酸与羟基取代的吲哚磺酰胺的反应或通过氨基或羟基取代的二氢吡啶与吲哚磺酰胺羧酸的反应来制备。 吲哚磺酰胺取代的二氢吡啶可用作用于治疗心脏，循环和血栓代谢紊乱的药物中的活性物质。
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公开(公告)号：US07712771B2
公开(公告)日：2010-05-11
申请号：US11900126
申请日：2007-09-10
申请人： Werner Freisler , Matthias Schramm
发明人： Werner Freisler , Matthias Schramm
IPC分类号： B60R21/16
CPC分类号： B60R21/231 , B60R21/206 , B60R21/2338 , B60R2021/23169 , B60R2021/23382
摘要： An airbag module has a module housing that has an airbag deployment opening with a predetermined opening dimension. An airbag is arranged folded in the module housing, the airbag having a first wall and a second wall situated opposite from the first wall. At least one holding means is arranged in the airbag. The at least one holding means is arranged in the unfolded airbag in the region of the airbag deployment opening and is attached on the airbag but not attached to the module housing. The holding means joins the first and second walls in the region of the airbag deployment opening and limits a distance between the walls in the region of the airbag deployment opening.
摘要翻译： 安全气囊模块具有模块壳体，其具有具有预定开口尺寸的气囊展开开口。 安全气囊被折叠在模块壳体中，气囊具有第一壁和与第一壁相对设置的第二壁。 至少一个保持装置设置在气囊中。 所述至少一个保持装置在所述展开的气囊中在所述气囊展开开口的区域中被布置，并且安装在所述气囊上，但未附接到所述模块壳体。 保持装置在气囊展开开口的区域中连接第一壁和第二壁，并限制气囊展开开口区域内的壁之间的距离。
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公开(公告)号：US20080067789A1
公开(公告)日：2008-03-20
申请号：US11900126
申请日：2007-09-10
申请人： Werner Freisler , Matthias Schramm
发明人： Werner Freisler , Matthias Schramm
IPC分类号： B60R21/16
CPC分类号： B60R21/231 , B60R21/206 , B60R21/2338 , B60R2021/23169 , B60R2021/23382
摘要： An airbag module has a module housing that has an airbag deployment opening with a predetermined opening dimension. An airbag is arranged folded in the module housing, the airbag having a first wall and a second wall situated opposite from the first wall. At least one holding means is arranged in the airbag. The at least one holding means is arranged in the unfolded airbag in the region of the airbag deployment opening and is attached on the airbag but not attached to the module housing. The holding means joins the first and second walls in the region of the airbag deployment opening and limits a distance between the walls in the region of the airbag deployment opening.
摘要翻译： 安全气囊模块具有模块壳体，其具有具有预定开口尺寸的气囊展开开口。 安全气囊被折叠在模块壳体中，气囊具有第一壁和与第一壁相对设置的第二壁。 至少一个保持装置设置在气囊中。 所述至少一个保持装置在所述展开的气囊中在所述气囊展开开口的区域中被布置，并且安装在所述气囊上，但未附接到所述模块壳体。 保持装置在气囊展开开口的区域中连接第一壁和第二壁，并限制气囊展开开口区域内的壁之间的距离。
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公开(公告)号：US5866571A
公开(公告)日：1999-02-02
申请号：US585996
申请日：1996-01-16
IPC分类号： C07D473/34 , A61K31/52 , A61K31/522 , A61K31/535 , A61K31/63 , A61K31/655 , A61P7/02 , A61P9/00 , A61P13/02 , A61P15/00 , A61P29/00 , A61P43/00 , C07D295/26 , C07D473/00 , C07D473/30
CPC分类号： C07D473/00 , C07D473/30
摘要： 9-Substituted 2-(2-n-alkoxyphenyl)purin-6-ones are prepared by cyclizing correspondingly substituted imidazoles and derivatizing the purines thus obtained. The 9-substituted .sup.2 -(2-n-alkoxyphenyl)purin-6-ones can be employed as active compounds in medicaments, in particular in medicarnents for treatment of inflammations, thromboembolic diseases and cardiovascular diseases.
摘要翻译： 9-取代的2-（2-正烷氧基苯基）嘌呤-6-酮通过环化相应取代的咪唑并衍生得到的嘌呤来制备。 9-取代的2-（2-正烷氧基苯基）嘌呤-6-酮可用作药物中的活性化合物，特别是用于治疗炎症，血栓栓塞性疾病和心血管疾病的药物。
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公开(公告)号：US5861404A
公开(公告)日：1999-01-19
申请号：US587321
申请日：1996-01-12
IPC分类号： A61K31/52 , A61K31/522 , A61P7/02 , A61P9/00 , A61P13/02 , A61P15/00 , A61P29/00 , A61P43/00 , C07D233/90 , C07D473/00 , C07D473/30
CPC分类号： C07D473/00
摘要： 2,9-Disubstituted purin-6-ones are prepared by acylating correspondingly substituted aminoimidazoles in a first step and then cyclizing the product to the purine. The new 2,9-disubstituted purin-6-ones can be employed as active compounds in medicaments, in particular for the treatment of inflammations, thromboembolic and cardiovascular diseases and diseases of the urogenital system.
摘要翻译： 2,9-二取代的嘌呤-6-酮通过在第一步中酰化相应的取代的氨基咪唑然后将产物环化成嘌呤来制备。 新的2,9-二取代的嘌呤-6-酮可以用作药物中的活性化合物，特别是用于治疗炎症，血栓栓塞和心血管疾病以及泌尿生殖系统的疾病。
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