公开(公告)号：US20050161859A1

公开(公告)日：2005-07-28

申请号：US11040864

申请日：2005-01-21

Applicant: Kathleen Miller ,  Gregory Sydney ,  Kurt Geitz ,  Peter Dayton ,  Ronald Sahatjian

Inventor： Kathleen Miller ,  Gregory Sydney ,  Kurt Geitz ,  Peter Dayton ,  Ronald Sahatjian

IPC: A61L27/00 ,  A61F2/84 ,  A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61M25/00 ,  B29D23/00

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents

Abstract translation: 公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。 特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法

公开(公告)号：US06755869B2

公开(公告)日：2004-06-29

申请号：US10057469

申请日：2002-01-25

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F236

CPC classification number: A61F5/0036 ,  A61B17/0469 ,  A61B2017/00004 ,  A61B2017/00867 ,  A61F2/0036

Abstract: A porous weave of bioabsorbable filaments having an open mesh configuration is formed into an oblate shape having dimensions greater than the esophageal opening and gastric outlet of a stomach. The resulting prosthesis is deployed in the stomach and is of a size to be retained in the proximate portion thereof for exerting pressure on the upper fundus. The prosthesis limits the amount of food that may be held within the stomach, and exerts pressure on the fundus to create a sensation of being full, resulting in weight loss.

公开(公告)号：US06740121B2

公开(公告)日：2004-05-25

申请号：US10057434

申请日：2002-01-25

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F236

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/0004

Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.