Cryogenic balloon ablation instruments and systems
    1.
    发明授权
    Cryogenic balloon ablation instruments and systems 有权
    低温球囊消融仪器和系统

    公开(公告)号:US08663211B2

    公开(公告)日:2014-03-04

    申请号:US13562150

    申请日:2012-07-30

    Abstract: A cryogenic tissue ablation instrument includes an elongate flexible body with a proximal supply port for coupling with a pressurized coolant, a supply lumen in communication with the proximal supply port, and an expandable balloon carried on the elongate body. A dispersion member coupled to the elongate body has an interior lumen in communication with the supply lumen, the dispersion member having one or more coolant dispersion apertures sized and located such that a pressurized flowable coolant will enter the balloon interior in the form of a liquid spray that contacts and provides substantially uniform cooling of the balloon.

    Abstract translation: 低温组织消融器具包括细长的柔性体,其具有用于与加压的冷却剂联接的近端供应口,与近端供应口连通的供应腔,以及承载在细长体上的可膨胀气囊。 耦合到细长主体的分散部件具有与供应内腔连通的内腔,分散部件具有一个或多个冷却剂分配孔,其尺寸和位置使得加压的可流动的冷却剂将以液体喷雾的形式进入气囊内部 其接触并提供气囊的基本上均匀的冷却。

    Devices and related methods for securing a tissue fold

    公开(公告)号:US20070162073A1

    公开(公告)日:2007-07-12

    申请号:US11715966

    申请日:2007-03-09

    Applicant: Kurt Geitz

    Inventor: Kurt Geitz

    Abstract: The present invention relates to devices and methods for creating and securing a tissue fold during an endoluminal medical procedure. The devices and methods may be used for folding and securing, for example, a fundus wall onto an esophagus wall. An aspect of the invention includes a two-piece tissue clip configured to be installed through an endoluminal device to secure a tissue fold. The clip includes a female member and a male member configured to engage one another to secure the tissue fold. Another aspect of the invention includes a clipping device comprising a tissue clip magazine. The magazine is configured to hold a plurality of tissue clips and install the plurality of tissue clips in a single actuation of the magazine. A method for using the clipping device together with the tissue clips of the present invention to create and secure a fold of tissue during an endoluminal procedure also is disclosed.

    Intragastric stent for duodenum bypass
    4.
    发明授权
    Intragastric stent for duodenum bypass 有权
    用于十二指肠旁路的内镜支架

    公开(公告)号:US07175669B2

    公开(公告)日:2007-02-13

    申请号:US11222666

    申请日:2005-09-09

    Applicant: Kurt Geitz

    Inventor: Kurt Geitz

    CPC classification number: A61F5/0076 A61F2/04 A61F2002/044 A61F2210/0004

    Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

    Abstract translation: 生物可吸收长丝的多孔织物被包裹在弹性膜中以形成薄壁支架。 该支架的尺寸设计成紧密地配合在患者十二指肠的近端部分中,以通过限制通过支架的食物的摄取而引起体重减轻。 经过一段预定的时间后,支架会从身体退化而不进行手术干预。

    Intragastric stent for duodenum bypass

    公开(公告)号:US20060030949A1

    公开(公告)日:2006-02-09

    申请号:US11222666

    申请日:2005-09-09

    Applicant: Kurt Geitz

    Inventor: Kurt Geitz

    CPC classification number: A61F5/0076 A61F2/04 A61F2002/044 A61F2210/0004

    Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

    Stents, stenting systems, and related methods for agent delivery
    6.
    发明授权
    Stents, stenting systems, and related methods for agent delivery 有权
    支架,支架系统和相关方法用于药剂输送

    公开(公告)号:US06939374B2

    公开(公告)日:2005-09-06

    申请号:US10024261

    申请日:2001-12-21

    Abstract: A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.

    Abstract translation: 一种用于插入身体管道或血管的腔的支架系统,用于将治疗剂递送到管道或血管上的治疗部位。 所述支架系统包括管状支架构件,所述管状支架构件具有内腔,以允许材料通过;附接至所述支架的外膜,所述支架的至少一部分对于所述治疗剂是多孔的,以允许所述药剂通过所述治疗部位 附着到支架上的内膜,其与治疗剂无关,以防止药剂进入支架的内腔,以及位于内膜和外膜之间用于保持治疗剂的腔室。 腔室中的治疗剂可以扩散通过膜的多孔部分并直接沉积在身体部位上。

    Implantable or insertable medical device resistant to microbial growth and biofilm formation
    7.
    发明授权
    Implantable or insertable medical device resistant to microbial growth and biofilm formation 有权
    可植入或可插入的医疗器械抗微生物生长和生物膜形成

    公开(公告)号:US09034346B2

    公开(公告)日:2015-05-19

    申请号:US13357033

    申请日:2012-01-24

    Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

    Abstract translation: 公开了可植入或可插入的医疗装置,其在装置的环境和环境中提供对微生物生长的抵抗力,并且抵抗微生物附着和在装置上的生物膜形成。 特别地,本发明公开了可植入或可插入的医疗装置,其包括至少一个生物相容性基质聚合物区域,用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法。

    Tissue patches and related delivery systems and methods
    9.
    发明申请
    Tissue patches and related delivery systems and methods 有权
    组织贴片和相关的递送系统和方法

    公开(公告)号:US20080312751A1

    公开(公告)日:2008-12-18

    申请号:US12216789

    申请日:2008-07-10

    Abstract: Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a substrate, a tissue implant attached to the substrate, and a protective liner covering at least a portion of the tissue implant. A method includes providing a tissue patch having a tissue implant attached to a substrate and a protective liner covering at least a portion of the tissue implant. The tissue patch is formed into a contracted state and inserted into a lumen containing the lesion. The tissue patch then is positioned in the vicinity of the lesion. After removing the protective liner to reveal the tissue implant, the tissue implant is placed in the lesion.

    Abstract translation: 公开了用于递送用于治疗消化道病变的组织贴片的内给药组织贴片和相关系统和方法。 组织贴片包括衬底,附着到衬底的组织植入物和覆盖组织植入物的至少一部分的保护衬垫。 一种方法包括提供具有附着到基底的组织植入物和覆盖组织植入物的至少一部分的保护性衬里的组织贴片。 组织贴片形成收缩状态并插入含有病变的内腔。 然后将组织贴片定位在病变附近。 在去除保护衬垫以露出组织植入物之后,将组织植入物放置在病变体内。

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