公开(公告)号：US11365451B2

公开(公告)日：2022-06-21

申请号：US16399467

申请日：2019-04-30

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Corporation

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

公开(公告)号：US20220162709A1

公开(公告)日：2022-05-26

申请号：US17600854

申请日：2020-04-03

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Corporation

Inventor： William R. Taylor ,  John B. Kisiel ,  Douglas W. Mahoney ,  David A. Ahlquist ,  Hatim T. Allawi

IPC: C12Q1/6886 ,  C12Q1/6806 ,  G01N33/574

Abstract: Provided herein is technology for pancreatic ductal adenocarcinoma (PDAC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of PDAC.

公开(公告)号：US20220136058A1

公开(公告)日：2022-05-05

申请号：US17297356

申请日：2019-11-26

Applicant: Exact Sciences Development Company, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： Hatim Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos ,  David A. Ahlquist ,  William R. Taylor ,  Douglas Mahoney

IPC: C12Q1/6886 ,  G01N33/574

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.

公开(公告)号：US20220106644A1

公开(公告)日：2022-04-07

申请号：US17424422

申请日：2020-01-24

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： William R. Taylor ,  John B. Kisiel ,  Douglas W. Mahoney ,  David A. Ahlquist ,  Hatim T. Allawi ,  Maria Giakoumopoulos

IPC: C12Q1/6886 ,  G16B30/10 ,  G16B35/20

Abstract: Provided herein is technology for endometrial cancer (EC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of endometrial cancer and various subtypes of endometrial cancer.

公开(公告)号：US20220071605A1

公开(公告)日：2022-03-10

申请号：US17233199

申请日：2021-04-16

Applicant: Exact Sciences Development Company, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： Robert F. Eisele ,  Michael E. Williams ,  Prasad G. Iyer ,  Paul Marrione ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos ,  William R. Taylor ,  Tracy C. Yab ,  Douglas W. Mahoney ,  John B. Kisiel ,  David A. Ahlquist

IPC: A61B10/02 ,  C12Q1/686 ,  A61B10/00

Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.

公开(公告)号：US20210381066A1

公开(公告)日：2021-12-09

申请号：US17410383

申请日：2021-08-24

Applicant: Exact Sciences Development Company, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： David A. Ahlquist ,  William R. Taylor ,  John B. Kisiel ,  Douglas W. Mahoney ,  Tracy C. Yab ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886 ,  C12Q1/6883 ,  G01N33/574

Abstract: Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).

公开(公告)号：US10975443B2

公开(公告)日：2021-04-13

申请号：US16202935

申请日：2018-11-28

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/68 ,  C07H21/04 ,  C12Q1/6886 ,  C12Q1/6853 ,  G16H50/30 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6827 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US20210102263A1

公开(公告)日：2021-04-08

申请号：US17120500

申请日：2020-12-14

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

公开(公告)号：US10900090B2

公开(公告)日：2021-01-26

申请号：US16242695

申请日：2019-01-08

Applicant: Mayo Foundation for Medical Education and Research

Inventor： John B. Kisiel ,  David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarcinoma.

公开(公告)号：US20200299778A1

公开(公告)日：2020-09-24

申请号：US16782841

申请日：2020-02-05

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  John B. Kisiel ,  Tracy C. Yab ,  Douglas W. Mahoney ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.