Methods for Concomitant Administration of Colchicine and a Second Active Agent
    41.
    发明申请
    Methods for Concomitant Administration of Colchicine and a Second Active Agent 有权
    秋水仙碱和第二活性剂的同时施用方法

    公开(公告)号:US20110190397A1

    公开(公告)日:2011-08-04

    申请号:US13092459

    申请日:2011-04-22

    申请人: Matthew W. Davis

    发明人: Matthew W. Davis

    IPC分类号: A61K31/165 A61P19/06

    摘要: Methods for concomitant administration of colchicine together with one or more second active agents, e.g., ketoconazole and ritonavir, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits. Methods of notifying health care practitioners and patients regarding appropriate dosing for concomitant administration of colchicine together with second active agents are also provided.

    摘要翻译: 公开了将秋水仙碱与一种或多种第二活性剂(例如酮康唑和利托那韦)一起施用的方法。 这样的方法减少了通常与这种伴随管理相关联的危险并提供额外的益处。 还提供了通知卫生保健从业者和患者关于适当给药的方法,以及与第二活性剂一起施用秋水仙素。

    Methods for concomitant administration of colchicine and a second active agent
    42.
    发明授权
    Methods for concomitant administration of colchicine and a second active agent 有权
    秋水仙素和第二活性剂的同时施用方法

    公开(公告)号:US07915269B2

    公开(公告)日:2011-03-29

    申请号:US12858667

    申请日:2010-08-18

    申请人: Matthew W. Davis

    发明人: Matthew W. Davis

    IPC分类号: A61K31/52 A61K31/16

    摘要: Methods for concomitant administration of colchicine together with one or more second active agents, e.g., ketoconazole and ritonavir, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits. Methods of notifying health care practitioners and patients regarding appropriate dosing for concomitant administration of colchicine together with second active agents are also provided.

    摘要翻译: 公开了将秋水仙碱与一种或多种第二活性剂(例如酮康唑和利托那韦)一起施用的方法。 这样的方法减少了通常与这种伴随管理相关联的危险并提供额外的益处。 还提供了通知卫生保健从业者和患者关于适当给药的方法,以及与第二活性剂一起施用秋水仙素。

    Methods for concomitant administration of colchicine and macrolide antibiotics
    45.
    发明授权
    Methods for concomitant administration of colchicine and macrolide antibiotics 有权
    秋水仙素和大环内酯类抗生素联合施用方法

    公开(公告)号:US07619004B1

    公开(公告)日:2009-11-17

    申请号:US12327258

    申请日:2008-12-03

    申请人: Matthew W. Davis

    发明人: Matthew W. Davis

    摘要: Methods for concomitant administration of colchicine together with one or more macrolide antibiotics, e.g., clarithromycin or erythromycin, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits. Methods of notifying health care practitioners and patients regarding appropriate dosing for co-administration of colchicine together with macrolide antibiotics are also provided.

    摘要翻译: 公开了将秋水仙碱与一种或多种大环内酯类抗生素(如克拉霉素或红霉素)同时施用的方法。 这样的方法减少了通常与这种伴随管理相关联的危险并提供额外的益处。 还提供了通知卫生保健从业者和患者关于合适施用秋水仙素与大环内酯类抗生素共同给药的方法。

    Carisoprodol, Phenytoin and Fosphenytoin Articles and Methods
    46.
    发明申请
    Carisoprodol, Phenytoin and Fosphenytoin Articles and Methods 审中-公开
    Carisoprodol,苯妥英和Fosphenytoin的文章和方法

    公开(公告)号:US20090118237A1

    公开(公告)日:2009-05-07

    申请号:US11865143

    申请日:2007-10-01

    摘要: A method of using carisoprodol, phenytoin or fosphenytoin comprises informing a user that co-administration of carisoprodol with phenytoin or fosphenytoin results in an increase in free phenytoin blood levels, a decrease in total phenytoin levels, or both. In another embodiment, a method of using carisoprodol, phenytoin or fosphenytoin comprises informing a user that when co-administering carisoprodol with phenytoin or fosphenytoin, the level of free phenytoin in a patient serum should be monitored, the level of total phenytoin should be monitored, or both. Also included are methods and articles of manufacture.

    摘要翻译: 使用加倍他索酚,苯妥英或氟苯妥英的方法包括通知使用者,加倍托酚与苯妥英或氟苯妥英的共同给药导致游离苯妥英血液水平升高,总苯妥英水平降低或两者均降低。 在另一个实施方案中,使用加倍他索酚,苯妥英或氟苯妥英的方法包括通知使用者当与托吡酯或苯妥英妥当同时给药时,应监测患者血清中游离苯妥英的水平,应监测总苯妥英的总量, 或两者。 还包括方法和制品。