公开(公告)号：US20210068950A1

公开(公告)日：2021-03-11

申请号：US17094909

申请日：2020-11-11

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

公开(公告)号：US20200253734A1

公开(公告)日：2020-08-13

申请号：US16858577

申请日：2020-04-24

Applicant: Medtronic, Inc.

Inventor： Damian Jelich ,  Ana Menk ,  Jason Quill ,  Gilbert Tang

IPC: A61F2/24

Abstract: A delivery system for delivery of a radially expandable device to an implantation site in a patient, the delivery system including an elongated tubular member comprising a distal tip and an outer surface, first and second balloon portions spaced proximally from each other and the distal tip along a length of the tubular member, an annular space between the first and second balloon portions, a plurality of clip deployment tubes extendably moveable relative to the outer surface of the tubular member, and a plurality of clips, wherein each clip is moveable within a length of one of the clip deployment tubes between a retracted position and a deployed position.

公开(公告)号：US10543079B2

公开(公告)日：2020-01-28

申请号：US15497376

申请日：2017-04-26

Applicant: Medtronic, Inc

Inventor： Jason Quill ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion. The inflow portion is formed from a plurality of struts that outwardly extend from the first end of the valve-retaining tubular portion with adjacent struts of the plurality of struts being joined, wherein each strut of the plurality of struts has a substantially s-shaped profile and at least one twisted area.

公开(公告)号：US10206775B2

公开(公告)日：2019-02-19

申请号：US14175100

申请日：2014-02-07

Applicant: Medtronic, Inc.

Inventor： Igor Kovalsky ,  Kshitija Garde ,  Pham Lo ,  Jason Quill ,  Padraig Savage

IPC: A61F2/24

Abstract: Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

公开(公告)号：US20180318080A1

公开(公告)日：2018-11-08

申请号：US16034061

申请日：2018-07-12

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Cynthia Clague ,  Michael Green ,  Alexander J. Hill ,  Ana Menk ,  Paul Rothstein ,  Georg Bortlein

IPC: A61F2/24 ,  A61B17/068 ,  A61B17/064 ,  A61B17/00

CPC classification number: A61F2/2442 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00331 ,  A61B2017/00349 ,  A61B2017/00783 ,  A61B2017/0649 ,  A61F2/2412 ,  A61F2002/249 ,  A61F2230/0091

Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.

公开(公告)号：US20180185142A1

公开(公告)日：2018-07-05

申请号：US15903642

申请日：2018-02-23

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Cynthia T. Clague ,  Paul T. Rothstein

IPC: A61F2/24

Abstract: Described is a prosthetic valve, comprising: an expandable stent including an inner lumen and having a first and a second end; and a spring attached to the first end of the expandable stent; wherein the expandable stent and the spring can expand radially to a desired diametric configuration in order to anchor the prosthetic valve at an implantation position in a body lumen. Related systems and methods.

公开(公告)号：US20140128963A1

公开(公告)日：2014-05-08

申请号：US13668085

申请日：2012-11-02

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Paul Rothstein ,  Thomas Secord ,  Byron Johnson

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/966 ,  A61F2002/9517 ,  A61F2250/0093

Abstract: A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis.

Abstract translation: 用于经皮部署阀门假体的输送系统。 该系统包括导管组件，其包括输送护套胶囊和具有振荡装置的手柄。 胶囊构造成在植入期间压缩地保持瓣膜假体。 在植入之后瓣膜假体被部分暴露之后，振动装置可产生振动运动，以减小瓣膜假体和输送鞘囊之间的摩擦，以便重新捕获瓣膜假体。

公开(公告)号：US20140114402A1

公开(公告)日：2014-04-24

申请号：US13659668

申请日：2012-10-24

Applicant: MEDTRONIC, INC.

Inventor： Sarah Ahlberg ,  Cynthia Clague ,  Brian McHenry ,  Susan Peterson ,  Scott Mosher ,  Karan Punga ,  Jason Quill

IPC: A61F2/24

CPC classification number: A61M25/0082 ,  A61B17/12036 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/12054 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0085 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0091 ,  A61F2250/006 ,  A61F2250/0069 ,  A61M31/005 ,  A61M2025/0087 ,  A61M2025/1052

Abstract: Devices and methods for delivering a sealing element post-implantation of valve prosthesis that functions to occlude or fill gaps present between the valve prosthesis and the native valve tissue, thereby reducing, minimizing, or eliminating leaks there through. In a first method, an injectable material is placed within a native valve sinus to form a sealing element that presses native valve leaflets against an outer surface of a heart valve prosthesis. In a second method, an injectable sealing material or a preformed annular sealing component is positioned between the outer surface or perimeter of a heart valve prosthesis and native heart valve tissue. In a third method, a preformed sealing element or component is placed within a heart valve prosthesis to press the prosthesis against native valve tissue.

Abstract translation: 用于递送瓣膜假体植入后的密封元件的装置和方法，其用于闭塞或填充阀门假体和天然瓣膜组织之间存在的间隙，从而减少，最小化或消除其中的泄漏。 在第一种方法中，将可注射材料放置在天然瓣膜内以形成密封元件，该密封元件将天然瓣膜压片压靠在心脏瓣膜假体的外表面上。 在第二种方法中，可注射密封材料或预成型的环形密封部件位于心脏瓣膜假体和天然心脏瓣膜组织的外表面或周边之间。 在第三种方法中，将预先形成的密封元件或部件放置在心脏瓣膜假体内以将假体按压于自然瓣膜组织。