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公开(公告)号:US20070237763A1
公开(公告)日:2007-10-11
申请号:US11544229
申请日:2006-10-06
申请人: Jacques Banchereau , Anna Palucka
发明人: Jacques Banchereau , Anna Palucka
IPC分类号: A61K39/395 , A61K45/00
CPC分类号: A01K67/0271 , A01K2227/105 , A01K2267/0331 , A61K38/1793 , A61K38/2086 , A61K39/395 , A61K45/06
摘要: The present invention includes compositions and methods for the treatment of cancers by controlling the type of immune response mounted against the tumor, and more particularly, the treatment of tumors with cytokine antagonists to change the type of helper T cell response and inhibition of angiogenesis, prevention of formation of metastasis and prevention of formation of tumor stroma.
摘要翻译: 本发明包括通过控制针对肿瘤的免疫应答的类型来治疗癌症的组合物和方法,更具体地,用细胞因子拮抗剂治疗肿瘤以改变辅助性T细胞应答的类型和抑制血管生成,预防 形成转移和预防肿瘤基质的形成。
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公开(公告)号:US06361939B1
公开(公告)日:2002-03-26
申请号:US08978289
申请日:1997-11-25
申请人: Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
发明人: Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
IPC分类号: C07H2104
CPC分类号: C07K14/70503 , C07K2319/00 , Y10S435/975
摘要: Polynucleotides encoding various dendritic cell specific proteins from a primate are provided. Uses of purified sequences are also disclosed, including producing related reagents, e.g., specific antibodies, and purified proteins. Methods of using these reagents and related diagnostic kits are also described.
摘要翻译: 提供了从灵长类动物编码各种树突状细胞特异性蛋白质的多核苷酸。 还公开了纯化序列的用途,包括产生相关试剂,例如特异性抗体和纯化的蛋白质。 还描述了使用这些试剂和相关诊断试剂盒的方法。
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