-
公开(公告)号:US20090275735A1
公开(公告)日:2009-11-05
申请号:US11930368
申请日:2007-10-31
申请人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
发明人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
IPC分类号: C07K16/00
CPC分类号: C07K14/715 , A61K38/00 , C07K14/52 , C07K16/244 , Y10S435/975
摘要: Human CTLA-8 protein, antibodies that specifically bind to human CTLA-8, and nucleic acids encoding human CTLA-8. Methods of using these molecules and diagnostic kits are also provided.
摘要翻译: 人CTLA-8蛋白,与人CTLA-8特异性结合的抗体,以及编码人CTLA-8的核酸。 还提供了使用这些分子和诊断试剂盒的方法。
-
公开(公告)号:US6063372A
公开(公告)日:2000-05-16
申请号:US736299
申请日:1996-10-24
申请人: Jacques Banchereau , Odile Djossou , Leopoldo Flores-Romo , Francois Fossiez , Pierre Golstein , Mala Krishna , Serge J. E. Lebecque , Richard Murray
发明人: Jacques Banchereau , Odile Djossou , Leopoldo Flores-Romo , Francois Fossiez , Pierre Golstein , Mala Krishna , Serge J. E. Lebecque , Richard Murray
CPC分类号: A61K38/193 , A61K38/20 , A61K38/204
摘要: Compositions and methods for using CTLA-8 to treat an abnormal physiological condition in an individual. The methods comprise administering a therapeutically effective amount of CTLA-8 alone, or in combination with other therapeutic reagents; or a CTLA-8 antagonist.
摘要翻译: 使用CTLA-8治疗个体异常生理状态的组合物和方法。 所述方法包括单独施用治疗有效量的CTLA-8或与其它治疗试剂组合施用; 或CTLA-8拮抗剂。
-
公开(公告)号:US06878528B1
公开(公告)日:2005-04-12
申请号:US09787192
申请日:1999-09-23
申请人: Valerie Duvert-Frances , Jean-Jacques Pin , Jenny Valladeau , Valerie Clair , Sem Saeland , Serge J. E. Lebecque
发明人: Valerie Duvert-Frances , Jean-Jacques Pin , Jenny Valladeau , Valerie Clair , Sem Saeland , Serge J. E. Lebecque
IPC分类号: C07K14/705 , C07K16/28 , C12P21/06
CPC分类号: C07K14/705 , C07K16/2851
摘要: Purified mammalian DC cell surface protein, designated Langerin, nucleic acids encoding Langerin, and antibodies which specifically bind Langerin.
摘要翻译: 纯化的哺乳动物DC细胞表面蛋白,命名为Langerin,编码Langerin的核酸和特异性结合Langerin的抗体。
-
公开(公告)号:US06706870B2
公开(公告)日:2004-03-16
申请号:US09929612
申请日:2001-08-13
申请人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
发明人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
IPC分类号: C07H2104
CPC分类号: C07K14/715 , A61K38/00 , C07K14/52 , C07K16/244 , Y10S435/975
摘要: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
-
公开(公告)号:US06361939B1
公开(公告)日:2002-03-26
申请号:US08978289
申请日:1997-11-25
申请人: Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
发明人: Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
IPC分类号: C07H2104
CPC分类号: C07K14/70503 , C07K2319/00 , Y10S435/975
摘要: Polynucleotides encoding various dendritic cell specific proteins from a primate are provided. Uses of purified sequences are also disclosed, including producing related reagents, e.g., specific antibodies, and purified proteins. Methods of using these reagents and related diagnostic kits are also described.
摘要翻译: 提供了从灵长类动物编码各种树突状细胞特异性蛋白质的多核苷酸。 还公开了纯化序列的用途,包括产生相关试剂,例如特异性抗体和纯化的蛋白质。 还描述了使用这些试剂和相关诊断试剂盒的方法。
-
公开(公告)号:US06277959B1
公开(公告)日:2001-08-21
申请号:US09111470
申请日:1998-07-08
申请人: Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人: Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
IPC分类号: A61K3900
CPC分类号: C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要: Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译: 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸,包括与其相关的灵长类动物,包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
公开(公告)号:US07879980B2
公开(公告)日:2011-02-01
申请号:US11930368
申请日:2007-10-31
申请人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques F. Banchereau
发明人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques F. Banchereau
IPC分类号: C07K16/00 , A61K39/395
CPC分类号: C07K14/715 , A61K38/00 , C07K14/52 , C07K16/244 , Y10S435/975
摘要: Human CTLA-8 protein, antibodies that specifically bind to human CTLA-8, and nucleic acids encoding human CTLA-8. Methods of using these molecules and diagnostic kits are also provided.
摘要翻译: 人CTLA-8蛋白,与人CTLA-8特异性结合的抗体,以及编码人CTLA-8的核酸。 还提供了使用这些分子和诊断试剂盒的方法。
-
公开(公告)号:US06933369B2
公开(公告)日:2005-08-23
申请号:US10349806
申请日:2003-01-22
申请人: Christopher G. Mueller , Serge J. E. Lebecque , Yong-Jun Liu , Lynette M. Dowling , Constance F. Huffine , Daniel M. Gorman
发明人: Christopher G. Mueller , Serge J. E. Lebecque , Yong-Jun Liu , Lynette M. Dowling , Constance F. Huffine , Daniel M. Gorman
CPC分类号: C12N9/0022 , A61K38/00 , C07K2319/00 , C12N9/16 , C12N9/6489 , Y10S435/975
摘要: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译: 描述了编码来自哺乳动物的各种蛋白酶,与其相关的试剂(包括特异性抗体)和纯化的蛋白质的核酸。 还提供使用所述试剂和相关诊断试剂盒的方法。
-
公开(公告)号:US06812004B1
公开(公告)日:2004-11-02
申请号:US08799028
申请日:1997-02-10
IPC分类号: C12N1519
CPC分类号: C07K14/523 , C07K2319/00
摘要: A novel CC chemokine which is from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokine. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的新型CC趋化因子,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述趋化因子的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
-
公开(公告)号:US06274711B1
公开(公告)日:2001-08-14
申请号:US08432994
申请日:1995-05-02
申请人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
发明人: Pierre Golstein , Eric Rouvier , Francois Fossiez , Serge J. E. Lebecque , Odile Djossou , Jacques Banchereau
IPC分类号: C07K1600
CPC分类号: C07K14/715 , A61K38/00 , C07K14/52 , C07K16/244 , Y10S435/975
摘要: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
-
-
-
-
-
-
-
-
-