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公开(公告)号：US06531005B1
公开(公告)日：2003-03-11
申请号：US09715785
申请日：2000-11-17
IPC分类号： C21D600
CPC分类号： B23P6/002 , C21D1/78 , C21D9/50 , C22C30/00 , C22C38/001 , C22C38/12 , C22C38/14 , F01D5/286
摘要： An article, made of a material such as a iron-nickel-base alloy, is weld repaired, and then heat treated. The heat treatment includes heating the weld-repaired portion to a first hold temperature of at least about 1775 degrees Fahrenheit, cooling the weld-repaired portion to a temperature of 1025 degrees Fahrenheit or less, heating the weld-repaired portion at a rate of at least about 10 degrees Fahrenheit per minute or greater, to a second hold temperature of at least about 1525 degrees Fahrenheit, cooling the weld-repaired portion to a third hold temperature of about 1425 degrees Fahrenheit or less, and cooling the weld-repaired portion to a fourth hold temperature of about 1225 degrees Fahrenheit or less.
摘要翻译： 由铁 - 镍基合金等材料制成的物品进行焊接修补，然后进行热处理。 热处理包括将焊接修复部分加热至至少约1775华氏度的第一保持温度，将焊接修复部分冷却至1025华氏度或更低的温度，以焊接修复部分的速度加热焊接修复部分 至少约10华氏度/分钟或更高，至至少约1525华氏度的第二保持温度，将焊接修补部分冷却至约1425华氏度或更低的第三保持温度，并将焊接修复部分冷却至 第四个保持温度约为1225华氏度或更低。
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公开(公告)号：US06297474B1
公开(公告)日：2001-10-02
申请号：US09472117
申请日：1999-12-23
IPC分类号： B23K916
摘要： A heating apparatus and method for pre-weld heat treating, welding and post-weld heat treating a superalloy article in a single enclosure while avoiding oxidation of the article. The enclosure is preferably equipped with a one-way valve that permits the escape of gases, but otherwise seals the enclosure to prevent the ingress of air during welding and heat treatment as a result of thermal gradients induced when the article is inductively heated. To provide access to the article and a device used to weld the article, the enclosure is equipped with gloves by which the welding device and the article can be manipulated while a nonreactive atmosphere is fully maintained within the enclosure and the article is inductively heating.
摘要翻译： 一种用于预焊接热处理，焊接和焊后热处理单个外壳中的超合金制品的加热装置和方法，同时避免制品的氧化。 外壳优选配备有允许气体逸出的单向阀，但是另外密封外壳，以防止在焊接和热处理期间进入空气，这是由于当物品被感应加热时引起的热梯度。 为了提供对物品的访问和用于焊接物品的装置，外壳配备有手套，通过该手套可以操纵焊接装置和物品，同时在壳体内完全保持非反应性气氛并且物品感应加热。
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43.发明授权
公开(公告)号：US5609698A
公开(公告)日：1997-03-11
申请号：US376519
申请日：1995-01-23
IPC分类号： C22F1/18
CPC分类号： C22F1/183
摘要： An as-cast gamma titanium-aluminide alloy, typically having a composition of from about 45.0 to about 48.5 atomic percent aluminum, is pre-HIP heat treated at a temperature of from about 1900.degree. F. to about 2100.degree. F. for a time of from about 50 to about 5 hours. The gamma titanium-aluminide alloy is thereafter hot isostatically pressed at a temperature of about 2200.degree. F. Hot isostatic pressing is preferably followed by a further heat treatment at a temperature of about 1850.degree.-2200.degree. F.
摘要翻译： 典型地具有约45.0至约48.5原子％铝的组成的铸态γ钛铝化物合金是在约1900°F至约2100°F的温度下进行预HIP热处理一段时间 为约50至约5小时。 然后，将γ钛 - 铝化物合金在约2200°F的温度下进行热等静压。优选在大约1850°-2200°F的温度下进行热等静压。
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公开(公告)号：US5545265A
公开(公告)日：1996-08-13
申请号：US405318
申请日：1995-03-16
IPC分类号： C22C14/00
CPC分类号： C22C14/00
摘要： A gamma titanium aluminide alloy is provided, based on the intermetallic compound TiAl, in which the resulting alloy is characterized by high creep strength and environmental resistance at elevated temperatures in excess of about 650.degree. C., and as high as about 850.degree. C. The alloy achieves these desirable properties through limited and interrelated additions of chromium, niobium and tantalum, whose combined amount is established by a minimum amount necessary to achieve a desired level of oxidation resistance.
摘要翻译： 提供了基于金属间化合物TiAl的γ钛铝化物合金，其中所得合金的特征在于超过约650℃和高达约850℃的高温蠕变强度和耐环境性。 该合金通过有限和相互关联的铬，铌和钽的添加来实现这些所需的性能，其组合量由达到所需水平的抗氧化性所需的最小量确定。
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公开(公告)号：US4811852A
公开(公告)日：1989-03-14
申请号：US161483
申请日：1988-02-29
申请人： Thomas J. Kelly
发明人： Thomas J. Kelly
CPC分类号： A47G25/743 , Y10S223/01
摘要： A portable tie holder which has a rectangular base and a plurality of movable arms for accommodating ties and like garments. Each arm includes a generally U-shaped rod having an axial end and a lateral end. Hinges are operatively associated with the axial ends of the arms allowing the arms to pivot relative the base. Locks mounted on the base releasably hold the lateral ends of the arms to locate the arms adjacent the base. A hook is mounted on the base whereby the holder may be hung on a fixture.
摘要翻译： 一种便携式领带保持器，其具有矩形基部和用于容纳纽带和类似服装的多个活动臂。 每个臂包括具有轴向端和横向端的大致U形的杆。 铰链与臂的轴向端部可操作地相关联，允许臂相对于基部枢转。 安装在基座上的锁定件可释放地保持臂的横向端部以使臂邻近基座。 钩子安装在基座上，由此保持器可以挂在固定装置上。
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公开(公告)号：USD286533S
公开(公告)日：1986-11-04
申请号：US554541
申请日：1983-11-23
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公开(公告)号：US4162390A
公开(公告)日：1979-07-24
申请号：US839027
申请日：1977-10-03
申请人： Thomas J. Kelly
发明人： Thomas J. Kelly
CPC分类号： B23K26/123 , B23K26/12 , B23K26/127
摘要： Apparatus and method for laser welding in a controllably pure gaseous environment at sub-atmospheric as well as high pressures. A workpiece to be welded is contained within a vessel having a light transmitting means which allows passage of a laser beam into the vessel. A gas stream is introduced to the vessel through a gas inlet means and positioned so that the stream deflects ionized particles from impinging on the light transmitting means. The gas stream simultaneously serves to cool the light transmitting means. Weld debris and spent gas are exhausted through a gas exhaust means which preferably is located adjacent to the workpiece. The apparatus is particularly suited to the laser welding of oxide dispersion strengthened alloys.
摘要翻译： 在低于大气压和高压的可控制的纯气体环境中激光焊接的装置和方法。 要焊接的工件被容纳在具有透光装置的容器中，该透光装置允许激光束通过容器。 通过气体入口装置将气流引入容器，并将其定位成使得该流使离子化的颗粒偏离撞击在光传输装置上。 气流同时用于冷却光传输装置。 焊接碎屑和废气通过优选位于工件附近的排气装置排出。 该设备特别适用于氧化物分散强化合金的激光焊接。
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公开(公告)号：US09180105B2
公开(公告)日：2015-11-10
申请号：US13583170
申请日：2011-03-08
IPC分类号： A61K31/352 , A61K31/365 , A61K31/7048 , A61P35/02 , A61P35/00 , A61K31/122
CPC分类号： A61K31/365 , A61K9/0019 , A61K31/122 , A61K31/352 , A61N5/10 , C07D493/08 , C07D493/18 , C09B13/02 , C09B61/00 , C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： The invention provides compounds, methods, pharmaceutical compositions, and kits for the treatment of proliferative disorders such as cancer. In one aspect, the methods comprise compounds that inhibit the activity of protein kinases, such as cell division cycle (Cdc) kinase. In another aspect, the methods comprise compounds that inhibit Cdc7 and/or Dbf4 activity. In another aspect, the methods comprise compounds that exhibit anti-proliferative properties useful in treating diseases such as cancer. Compounds useful for any of the methods include compounds of the Formula (A) or (B) or pharmaceutically acceptable salts thereof. Exemplary compounds of Formula (A) or (B) include granaticin A, granaticin B, dihydrogranaticin A, dihydrogranaticin B, medermycin, and actinorhodin.
摘要翻译： 本发明提供了用于治疗增殖性疾病如癌症的化合物，方法，药物组合物和试剂盒。 在一个方面，所述方法包括抑制蛋白激酶如细胞分裂周期（Cdc）激酶活性的化合物。 另一方面，所述方法包括抑制Cdc7和/或Dbf4活性的化合物。 另一方面，该方法包括表现出抗增殖性质的化合物，其可用于治疗诸如癌症的疾病。 可用于任何方法的化合物包括式（A）或（B）的化合物或其药学上可接受的盐。 式（A）或（B）的示例性化合物包括：颗粒状颗粒A，颗粒状蛋白B，二氢大戟素A，二氢巨球蛋白B，医药霉素和放线菌素。
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49.发明申请公开(公告)号：US20120198038A1
公开(公告)日：2012-08-02
申请号：US13017027
申请日：2011-01-30
申请人： Kevin Porter , Thomas J. Kelly , Marcin Lukasz Lizon , Darrell Long , Eric Maki , Kim Tremblay , Jennifer Vance
发明人： Kevin Porter , Thomas J. Kelly , Marcin Lukasz Lizon , Darrell Long , Eric Maki , Kim Tremblay , Jennifer Vance
IPC分类号： G06F15/173
CPC分类号： H04L41/0893 , H04L41/082 , H04L41/5054 , H04L67/2852
摘要： A policy distribution server provides, on a subscription basis, policy updates to effect desired behaviors of network intermediary devices. The policy updates may specify caching policies, and may in some instances, include instructions for data collection by the network intermediary devices. Data collected in accordance with such instructions may be used to inform future policy updates distributed to the network intermediary devices.
摘要翻译： 策略分发服务器在订阅的基础上提供策略更新以实现网络中间设备的期望行为。 策略更新可以指定高速缓存策略，并且在某些情况下可以包括由网络中间设备收集数据的指令。 根据这样的指令收集的数据可用于通知分发给网络中间设备的未来策略更新。
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50.发明申请公开(公告)号：US20120158815A1
公开(公告)日：2012-06-21
申请号：US13285481
申请日：2011-10-31
申请人： Thomas J. Kelly , Kevin Porter , Eric Maki , Marcin Lukasz Lizon , Marsha Groves
发明人： Thomas J. Kelly , Kevin Porter , Eric Maki , Marcin Lukasz Lizon , Marsha Groves
IPC分类号： G06F15/16
CPC分类号： G06F17/30902
摘要： A caching device is configured to determine whether an object received or currently stored at the caching device should be (or continue to be) cached at the caching device, even if the object is otherwise cacheable. If so, the object is cached (or retained) at the caching device, otherwise, it is not. The determination as to whether or not the object should be cached or, if already cached, retained at the caching device may be made on the basis of a worthiness determination which evaluates the object on the basis of one or more parameters or attributes of the object, which worthiness may be one part of an overall value determination for the object.
摘要翻译： 缓存设备被配置为确定在高速缓存设备处接收或当前存储的对象是否应该（或继续地）被缓存在高速缓存设备上，即使该对象是可高速缓存的。 如果是这样，对象被缓存（或保留）在缓存设备上，否则不是。 关于对象是否被缓存的确定，或者如果缓存保留在高速缓存设备上，可以基于基于对象的一个或多个参数或属性来评估对象的可靠性确定来进行 ，这个价值可能是对象的整体价值确定的一部分。
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