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73 条记录 (耗时 0.035 秒)

    Compounds suitable as modulators of HDL
    41.
    发明授权
    Compounds suitable as modulators of HDL 失效
    适合作为HDL调节剂的化合物

    公开(公告)号：US08022217B2

    公开(公告)日：2011-09-20

    申请号：US12374089

    申请日：2007-07-27

    申请人： Pravin S. Thombare ,  Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Pankaj Ramanbhai Patl

    发明人： Pravin S. Thombare ,  Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Pankaj Ramanbhai Patl

    IPC分类号： C07D215/38

    CPC分类号： C07C237/30 ,  C07C2601/14 ,  C07D215/48 ,  C07D405/12

    摘要： Disclosed herein in the embodiments of the present invention are the compounds suitable as modulators of HDL having general formula (1), novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (1), their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

    摘要翻译： 在本发明的实施方案中公开的是适合作为具有通式（1）的HDL的调节剂的化合物，涉及其合成的新中间体，其药学上可接受的盐和含有它们的药物组合物。 本发明还涉及制备通式（1）的化合物，其互变异构形式，其药学上可接受的盐，含有它们的药物组合物和参与其合成的新中间体的方法。

    Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
    50.
    发明授权
    Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine 有权
    杂环化合物，它们的制备，含有它们的药物组合物及其在医药中的用途

    公开(公告)号：US08110598B2

    公开(公告)日：2012-02-07

    申请号：US12018555

    申请日：2008-01-23

    申请人： Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Vijay Kumar Gajubhai Barot

    发明人： Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Vijay Kumar Gajubhai Barot

    IPC分类号： A61K31/40 ,  C07D295/02 ,  C07D207/30

    CPC分类号： C07D207/325 ,  C07D207/33 ,  C07D207/333 ,  C07D207/335 ,  C07D207/36 ,  C07D207/48 ,  C07D401/04 ,  C07D405/04 ,  C07D409/04 ,  G06F3/14 ,  G06F3/1438 ,  G09G5/363 ,  G09G2360/122

    摘要： The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel substituted pyrrole compounds of the general formula (I), their analogs, their derivatives, their polymorphs, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and their pharmaceutical compositions containing them. This invention also relates to the process for preparing such compounds, a composition containing such a compound and the use of such a compound and composition in medicine.

    摘要翻译： 本发明涉及新的取代吡咯化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和含有它们的药学上可接受的组合物。 本发明特别涉及通式（I）的新型取代吡咯化合物，其类似物，其衍生物，其多晶型物，其互变异构形式，其药学上可接受的盐，其药学上可接受的溶剂合物及其含有它们的药物组合物。 本发明还涉及制备这种化合物的方法，含有这种化合物的组合物以及这种化合物和组合物在医药中的用途。