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41.发明申请PHARMACEUTICAL COMPOSITION COMPRISING EICOSAPENTAENOIC ACID AND NICOTINIC ACID AND METHODS OF USING SAME 审中-公开包含苹果酸和非丁酸的药物组合物及其使用方法公开(公告)号：US20130095178A1
公开(公告)日：2013-04-18
申请号：US13705990
申请日：2012-12-05
发明人： Mehar Manku
IPC分类号： A61K31/202 , A61K31/232 , A61K45/06 , A61K31/455
CPC分类号： A61K31/202 , A61K31/232 , A61K31/455 , A61K45/06 , A61K2300/00
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
摘要翻译： 本发明尤其涉及包含二十碳五烯酸和/或其衍生物和烟酸的药物组合物，涉及制备该组合物的方法，以及治疗龋齿疾病和病症的治疗方法。
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公开(公告)号：US08377920B2
公开(公告)日：2013-02-19
申请号：US13623450
申请日：2012-09-20
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US20130004572A1
公开(公告)日：2013-01-03
申请号：US13614146
申请日：2012-09-13
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K9/48 , A61K31/232 , A61P9/00 , A61P9/10 , A61P9/04 , A61P7/02 , A61P3/10 , A61P25/00 , A61P7/10 , A61P9/12 , A61P11/00 , A61P1/16 , A61P3/06 , A61P3/00 , A61P3/04 , A61P9/06 , A61K31/202
CPC分类号： A61K31/202 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/232 , A61K45/06
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
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公开(公告)号：US20130004567A1
公开(公告)日：2013-01-03
申请号：US13608775
申请日：2012-09-10
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K31/232 , A61P3/06 , A61P9/00 , A61K9/48
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US20130004566A1
公开(公告)日：2013-01-03
申请号：US13608744
申请日：2012-09-10
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K31/232 , A61P3/06 , A61P9/00 , A61K9/48
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof
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公开(公告)号：US20120225120A1
公开(公告)日：2012-09-06
申请号：US13458496
申请日：2012-04-27
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K9/48 , A61P3/06 , A61K31/232
CPC分类号： A61K31/202 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/232 , A61K45/06
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
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47.发明公开公开(公告)号：US20240165066A1
公开(公告)日：2024-05-23
申请号：US18472875
申请日：2023-09-22
IPC分类号： A61K31/202 , A61K31/5575 , A61K31/685 , A61P11/00
CPC分类号： A61K31/202 , A61K31/5575 , A61K31/685 , A61P11/00
摘要： Provided are compositions comprising one or more polyunsaturated fatty acids or derivatives thereof, a source of phospholipid, and optionally one or more additional emulsifiers, as well as methods of using the same to treat various diseases. In some embodiments, provided is a lymph-releasing composition of eicosapentaenoic acid ethyl ester (LR-EtEPA) and methods of using the same to increase EPA uptake in tissues and to treat various diseases including cardiopulmonary diseases, renal diseases, neurological diseases, and cancer.
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48.发明公开公开(公告)号：US20240016803A1
公开(公告)日：2024-01-18
申请号：US18151382
申请日：2023-01-06
发明人： George Grandolfi
IPC分类号： A61K31/505 , A61K31/232 , A61K31/202 , A61K31/22 , A61K31/366 , A61K31/40 , A61P9/04 , A61P9/10 , A61P9/12 , A61P9/00
CPC分类号： A61K31/505 , A61K31/232 , A61K31/202 , A61K31/22 , A61K31/366 , A61K31/40 , A61P9/04 , A61P9/10 , A61P9/12 , A61P9/00
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and a statin and to methods of using the same to treat or prevent cardiovascular-related diseases.
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49.发明授权公开(公告)号：US11547710B2
公开(公告)日：2023-01-10
申请号：US16193131
申请日：2018-11-16
发明人： George Grandolfi
IPC分类号： A61K31/505 , A61K31/202 , A61K31/22 , A61K31/232 , A61K31/366 , A61K31/40 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and a statin and to methods of using the same to treat or prevent cardiovascular-related diseases.
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公开(公告)号：US20220323392A1
公开(公告)日：2022-10-13
申请号：US17582886
申请日：2022-01-24
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/202
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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