公开(公告)号：US20210307985A1

公开(公告)日：2021-10-07

申请号：US17219330

申请日：2021-03-31

申请人： The University of Kansas

发明人： Jared STAAB ,  Brent BARTA ,  Brigid FLYNN ,  Tim KRAUSE ,  Jay NACHTIGAL

IPC分类号： A61G10/00 ,  A61G10/02

摘要： An aerosolization mitigation device is provided. The aerosolization mitigation device can include a negative pressure aerosolization mitigation system. A transparent barrier can form a frame of the system, and a negative pressure can be generated in the internal volume. The device can isolate a patient to allow ambulatory, surgical, and routine care to proceed during periods of higher patient volume or viral transmission. The negative pressure environment mitigates viral transmission to protect healthcare providers and others in the vicinity of the patient from health risks during patient care.

公开(公告)号：US11130736B2

公开(公告)日：2021-09-28

申请号：US15754193

申请日：2016-08-19

申请人： UNIVERSITY OF KANSAS

发明人： Sunil A. David ,  Mallesh Beesu ,  Giuseppe Caruso ,  Alex Salyer

IPC分类号： C07D215/38 ,  A61P37/02 ,  A61K45/06 ,  A61K39/39

摘要： The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.

公开(公告)号：US11129656B2

公开(公告)日：2021-09-28

申请号：US15819073

申请日：2017-11-21

申请人： University of Kansas

发明人： Terence Edward McIff ,  Edward Bruce Toby

IPC分类号： A61B17/064 ,  A61B17/86 ,  A61B17/68 ,  A61B17/00

摘要： Embodiments of the present invention relate to systems, methods, and apparatus for immobilizing and/or securing bone portions. Particularly, at least one embodiment involves a compact anti-rotation device that can secure adjacent bones and/or bone portions in a manner that prevents or limits relative rotational movement thereof.

公开(公告)号：US20210277817A1

公开(公告)日：2021-09-09

申请号：US17260102

申请日：2019-08-30

申请人： University of Kansas

发明人： Christopher Depcik ,  Matthew Cole

IPC分类号： F01N11/00 ,  F01N9/00

摘要： Systems, methods, and computer readable storage media for controlling oxidation of a particulate filter (PF) are closed. The oxidation of the PF may be controlled using a PF model. The PF model may be utilized to simulate operations of the PF based on various input data and/or derived data to determine an optimum time for initiating an oxidation event at the PF, and an oxidation event may be initiated at the PF based on the simulating.

公开(公告)号：US20210268121A1

公开(公告)日：2021-09-02

申请号：US17236561

申请日：2021-04-21

申请人： The University of Kansas ,  Kansas State University Research Foundation

发明人： Mei He

IPC分类号： A61K47/69 ,  G01N33/543 ,  G01N33/574

摘要： Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments.

公开(公告)号：US20210132211A1

公开(公告)日：2021-05-06

申请号：US17086006

申请日：2020-10-30

申请人： University of Kansas ,  Government of the United States, as represented by the Secretary of the Air Force

发明人： Patrick M. McCormick ,  Cenk Sahin ,  Shannon David Blunt ,  Justin G. Metcalf

IPC分类号： G01S13/538 ,  G01S7/00

摘要： Systems and methods of embodiments provide a feasible approach to implementing Far-Field Radiated Emission Design (FFRED) techniques suitable for simultaneous transmission of radar and communication signals. A set of signals for transmission and a transmission direction for each signal of the set of signals may be determined. The set of signals includes at least a first signal associated with a first transmission direction and a second signal associated with a second transmission direction that is different from the first direction. An optimization problem is configured based on characteristics of an antenna array and the set of signals and then solved to identify a set of waveforms suitable for transmitting the signals. The set of waveforms may include at least two waveforms, each of the at least two waveforms configured for transmission by a different antenna element of the antenna array. The determined waveforms may be coherent in the far-field and suitable for power efficient transmission.

公开(公告)号：US10985393B2

公开(公告)日：2021-04-20

申请号：US16040857

申请日：2018-07-20

申请人： University of Kansas

发明人： Trung Van Nguyen ,  Regis P. Dowd, Jr.

IPC分类号： H01M8/1004 ,  H01M8/0258 ,  H01M4/90 ,  H01M4/86 ,  H01M8/1018

摘要： In embodiments, a method of forming a membrane electrode assembly comprises pressing a stack comprising a cathode, an anode, a proton exchange membrane between the cathode and the anode, and a porous catalyst layer in contact with the proton exchange membrane, the porous catalyst layer comprising an ionomer, the ionomer coating internal surfaces of pores of the porous catalyst layer, thereby providing internal ionomer-gas interfaces within the porous catalyst layer; for a time, a pressure, and a temperature to bind the ionomer to the proton exchange membrane, whereby steam is generated within the porous catalyst layer. The steam is removed via pores of the porous catalyst layer to increase the hydrophobicity of the internal ionomer-gas interfaces within the porous catalyst layer.

公开(公告)号：US20210107623A1

公开(公告)日：2021-04-15

申请号：US17047779

申请日：2019-04-16

申请人： University of Kansas

发明人： Ronald Martin Barrett ,  Lauren Nicole Schumacher ,  Patrick Ian McNamee ,  John Austin Haug ,  Joshua Donald Mudd ,  Dalton Bastiaan Prins ,  Nicholas Donald Werner

IPC分类号： B64C11/00 ,  B64C27/20 ,  B64C33/00 ,  F01D25/04

摘要： A general mounting method for ducted fan propulsors is disclosed. This mounting method uses extremely slender stators that connect the duct ring to the propulsor which is mounted in the middle and drives the rotor, fan or propeller. The slender stators take the form of spokes and as such are so slender that the midspan stresses within the spokes are dominated by axial tension loads rather than the shear loads experienced by conventional stators. The spokes may have an aerodynamic shape and damping methods may be used to retard spoke vibrations and transmission of engine vibrations to the duct and force. The duct itself is also stiffened by the spoke arrangement, thereby reducing low frequency vibration modes.

公开(公告)号：US20210027475A1

公开(公告)日：2021-01-28

申请号：US16982226

申请日：2019-03-22

申请人： University of Kansas

发明人： Xiangxiong Kong ,  Jian Li

IPC分类号： G06T7/33 ,  G06T7/00 ,  G01N21/88 ,  G06T7/11

摘要： A computer vision-based fastener loosening detection approach is described. A first image is captured at a first time and a second image is captured at a second time. A feature-based image registration is performed to create a third image. An intensity-based image registration is performed to create a fourth image. Registration errors are determined based on a comparison of the first and fourth images. A feature enhancement process is performed on the registration errors to determine whether the fastener has loosened between the first time and the second time.

公开(公告)号：US20210024576A1

公开(公告)日：2021-01-28

申请号：US16982638

申请日：2019-03-22

申请人： University of Kansas ,  University of Florida

发明人： Jane Aldrich ,  Sanjeewa Senadheera ,  Jay McLaughlin

IPC分类号： C07K5/12 ,  A61K38/00 ,  A61K9/00

摘要： The present technology provides compounds of Formula I (or pharmaceutically acceptable salts and/or solvates thereof) that are useful in treating a CNS-related disorder such as schizophrenia, schizoaffective disorder, migraine, depression, pain, drug addiction, drug use, and/or drug seeking behavior. Also provided are compositions, medicaments, and methods including such compounds.