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51.
公开(公告)号:US20230000497A1
公开(公告)日:2023-01-05
申请号:US17867990
申请日:2022-07-19
申请人: Pulmonx Corporation
发明人: Nikolai Aljuri , Rodney C. Perkins , Niyazi Beyhan
摘要: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.
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公开(公告)号:US11317825B2
公开(公告)日:2022-05-03
申请号:US16432685
申请日:2019-06-05
申请人: Pulmonx Corporation
发明人: Surag Mantri
摘要: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.
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公开(公告)号:US11304742B2
公开(公告)日:2022-04-19
申请号:US16590804
申请日:2019-10-02
申请人: Pulmonx Corporation
发明人: Peter P. Soltesz , Nikolai Aljuri , Ajit Nair
IPC分类号: A61B18/14 , A61B18/00 , A61B18/08 , A61B18/02 , A61B18/12 , A61B18/18 , A61M16/00 , A61M16/04 , A61N5/10 , A61N7/02 , A61B18/20 , A61B18/04
摘要: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.
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公开(公告)号:US20220007967A1
公开(公告)日:2022-01-13
申请号:US17363667
申请日:2021-06-30
申请人: Pulmonx Corporation
发明人: Sri Radhakrishnan , Ryan Olivera
摘要: Methods and systems for determining collateral ventilation are disclosed. Methods may comprise introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, inflating the occluding member to isolate the lung compartment, and performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device. The diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device. The presence collateral ventilation may be determined based on the exhaled volume from the isolated lung compartment over the predetermined period of time.
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公开(公告)号:US20210330441A1
公开(公告)日:2021-10-28
申请号:US17366727
申请日:2021-07-02
申请人: Pulmonx Corporation
发明人: Ryan Olivera , Hoang Nguyen
摘要: Devices, methods, and systems are provided for loading an implantable device into a container. One aspect of the loading system contains a loader element with a loading tunnel that is configured to gradually contract an implantable device into a compressed state of reduced size relative to an expanded state as the implantable device travels through the loading tunnel.
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公开(公告)号:US10932706B2
公开(公告)日:2021-03-02
申请号:US16107849
申请日:2018-08-21
申请人: Pulmonx Corporation
IPC分类号: A61B5/1455 , A61B5/08 , A61M16/04 , A61B5/085 , A61B1/00 , A61B1/267 , A61B5/087 , A61B5/145 , A61B5/00 , A61M16/00 , A61B5/091 , A61M16/10
摘要: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.
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公开(公告)号:US20200038086A1
公开(公告)日:2020-02-06
申请号:US16590804
申请日:2019-10-02
申请人: Pulmonx Corporation
发明人: Peter P. Soltesz , Nikolai Aljuri , Ajit Nair
IPC分类号: A61B18/00 , A61B18/20 , A61N7/02 , A61N5/10 , A61M16/04 , A61M16/00 , A61B18/18 , A61B18/14 , A61B18/12 , A61B18/02 , A61B18/08
摘要: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.
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公开(公告)号:US10314516B2
公开(公告)日:2019-06-11
申请号:US15159670
申请日:2016-05-19
申请人: PulmonX Corporation
发明人: Surag Mantri
摘要: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.
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公开(公告)号:US20180092731A1
公开(公告)日:2018-04-05
申请号:US15714868
申请日:2017-09-25
申请人: Pulmonx Corporation
发明人: Sri Radhakrishnan , Ryan Olivera
摘要: Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. An exemplary flow control device is configured to block fluid flow in the inspiratory direction and the expiratory direction at normal breathing pressures and allow fluid flow in the expiratory direction at coughing pressures.
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公开(公告)号:US09592008B2
公开(公告)日:2017-03-14
申请号:US13174565
申请日:2011-06-30
CPC分类号: A61F2/04 , A61B1/018 , A61B1/2676 , A61B5/1076 , A61B5/6852 , A61B17/12104 , A61B2017/0034 , A61B2090/061 , A61F2002/043 , A61M2025/0008
摘要: Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.
摘要翻译: 公开了用于测量人或动物受试者中气道直径的装置,系统和方法。 该装置包括具有近端和远端的柔性导管本体。 灵活的施胶元件沿导管本体大致正交地设置并延伸。 尺寸调节元件彼此具有不同的高度,并且被配置成穿过支气管镜的工作通道。 还公开了用于将气流重定向通过肺气道的装置,系统和方法。 该方法包括将包括远端,近端和其间的细长部分的导管引入气道中,其中远端包括气道关闭机构,并且其中近端包括用于致动气道闭合机构的致动器; 并且致动气道关闭机构以至少部分地关闭气道。
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