Preparation of anhydrous 2-amino-1-methoxypropane
    52.
    发明授权
    Preparation of anhydrous 2-amino-1-methoxypropane 失效
    无水2-氨基-1-甲氧基丙烷的制备

    公开(公告)号:US5910612A

    公开(公告)日:1999-06-08

    申请号:US82543

    申请日:1998-05-21

    CPC分类号: C07C213/02 C07C213/10

    摘要: The process for preparing anhydrous 2-amino-1-methoxypropane proceeds by(a) admixing a 2-amino-1-methoxypropane-containing water-containing reaction mixture, obtainable from the reaction of 1-methoxy-2-propanol with ammonia on a catalyst, with sodium hydroxide solution, forming an aqueous phase containing sodium hydroxide solution and a 2-amino-1-methoxypropane-containing phase,(b) separating off the 2-amino-1-methoxypropane-containing phase from the aqueous phase and(c) distilling the 2-amino-1-methoxypropane-containing phase, an azeotrope of water and 2-amino-1-methoxypropane, which is recycled to step (a) or (b), first being produced and anhydrous 2-amino-1-methoxypropane then being produced.

    摘要翻译: 制备无水2-氨基-1-甲氧基丙烷的方法是:(a)将可从1-甲氧基-2-丙醇反应得到的含2-氨基-1-甲氧基丙烷的含水反应混合物与氨混合, 催化剂,用氢氧化钠溶液,形成含有氢氧化钠溶液和含2-氨基-1-甲氧基丙烷的相的水相,(b)从水相中分离出含2-氨基-1-甲氧基丙烷的相和( c)蒸馏出含有2-氨基-1-甲氧基丙烷的相,再循环至步骤(a)或(b)的水和2-氨基-1-甲氧基丙烷的共沸物,首先制得无水2-氨基-1-甲氧基丙烷, 然后生产1-甲氧基丙烷。