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公开(公告)号：US11058584B2
公开(公告)日：2021-07-13
申请号：US16692839
申请日：2019-11-22
申请人： Michael S. Berlin
发明人： Michael S. Berlin
IPC分类号： A61B3/00 , A61F9/008 , A61B3/10 , A61B3/13 , A61B3/14 , A61B34/20 , G06T11/60 , A61F9/007 , A61B90/00 , A61B34/00 , A61B90/20 , G06T7/00
摘要： Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.
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公开(公告)号：US11058582B2
公开(公告)日：2021-07-13
申请号：US17248543
申请日：2021-01-28
申请人： Michael S. Berlin
发明人： Michael S. Berlin
摘要： An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe 500 can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe 500 can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe 500 may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.
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公开(公告)号：US20210145641A1
公开(公告)日：2021-05-20
申请号：US17248546
申请日：2021-01-28
申请人： Michael S. BERLIN
发明人： Michael S. BERLIN
摘要： An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe 500 can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe 500 can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe 500 may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.
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公开(公告)号：US20200229971A1
公开(公告)日：2020-07-23
申请号：US16692839
申请日：2019-11-22
发明人： Michael S. Berlin
摘要： Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.
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公开(公告)号：US10383689B2
公开(公告)日：2019-08-20
申请号：US10640464
申请日：2003-08-12
申请人： Michael S. Berlin
发明人： Michael S. Berlin
摘要： A method and delivery system are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and Schlemm's canal of an eye for reducing elevated intraocular pressure. Pulsed laser radiation is delivered from the distal end of a fiber-optic probe sufficient to cause photoablation of selected portions of the trabecular meshwork, the juxtacanalicular trabecular meshwork and an inner wall of Schlemm's canal in the target site. The fiber-optic probe may be advanced so as to create an aperture in the inner wall of Schlemm's canal in which fluid from the anterior chamber of the eye flows. The method and delivery system may further be used on any tissue types in the body.
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56.发明申请公开(公告)号：US20190083314A1
公开(公告)日：2019-03-21
申请号：US16008917
申请日：2018-06-14
申请人： Michael S. Berlin
发明人： Michael S. Berlin
CPC分类号： A61F9/00825 , A61F9/0084 , A61F9/009 , A61F2009/00851 , A61F2009/00865 , A61F2009/00868 , A61F2009/00891 , A61F2009/00897
摘要： Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be effected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.
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公开(公告)号：US20180360310A1
公开(公告)日：2018-12-20
申请号：US16011011
申请日：2018-06-18
申请人： Michael S. Berlin
发明人： Michael S. Berlin
摘要： Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.
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58.发明授权公开(公告)号：US10064757B2
公开(公告)日：2018-09-04
申请号：US14732627
申请日：2015-06-05
申请人： Michael S. Berlin
发明人： Michael S. Berlin
摘要： Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be effected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.
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公开(公告)号：US20180221205A1
公开(公告)日：2018-08-09
申请号：US15808809
申请日：2017-11-09
申请人： Michael S. BERLIN
发明人： Michael S. BERLIN
CPC分类号： A61F9/00781 , A61F9/00736 , A61F9/00802 , A61F2009/00868 , A61F2009/00891
摘要： A method and delivery system are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and Schlemm's canal of an eye for reducing elevated intraocular pressure. Pulsed laser radiation is delivered from the distal end of a fiber-optic probe sufficient to cause photoablation of selected portions of the trabecular meshwork, the juxtacanalicular trabecular meshwork and an inner wall of Schlemm's canal in the target site. The fiber-optic probe may be advanced so as to create an aperture in the inner wall of Schlemm's canal in which fluid from the anterior chamber of the eye flows. The method and delivery system may further be used on any tissue types in the body.
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公开(公告)号：US09820883B2
公开(公告)日：2017-11-21
申请号：US09860842
申请日：2001-05-21
申请人： Michael S. Berlin
发明人： Michael S. Berlin
CPC分类号： A61F9/00 , A61B17/32 , A61B2017/00017 , A61B2017/00022 , A61B2017/00026 , A61B2017/00039 , A61B2017/00057 , A61B2017/00066 , A61B2017/00092 , A61B2017/00119 , A61B2018/00011 , A61B2018/00196 , A61B2018/00321 , A61B2018/00577 , A61B2018/00648 , A61B2018/00904 , A61B2018/00982 , A61B2018/2255 , A61F2/14 , A61F2/15 , A61F9/00781 , A61F9/008 , A61F9/00802 , A61F2009/00844 , A61F2009/00868
摘要： A method and delivery system are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and Schlemm's canal of an eye for reducing elevated intraocular pressure. Pulsed laser radiation is delivered from the distal end of a fiber-optic probe sufficient to cause photoablation of selected portions of the trabecular meshwork, the juxtacanalicular trabecular meshwork and an inner wall of Schlemm's canal in the target site. The fiber-optic probe may be advanced so as to create an aperture in the inner wall of Schlemm's canal in which fluid from the anterior chamber of the eye flows. The method and delivery system may further be used on any tissue types in the body.
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