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130 条记录 (耗时 0.033 秒)

    PDE1 inhibitors for ophthalmic disorders
    51.
    发明授权
    PDE1 inhibitors for ophthalmic disorders 有权

    公开(公告)号：US11464781B2

    公开(公告)日：2022-10-11

    申请号：US13203365

    申请日：2010-02-24

    申请人： Robert Davis ,  Allen Fienberg

    发明人： Robert Davis ,  Allen Fienberg

    IPC分类号： A61K31/535 ,  A61K9/00 ,  A61K31/5575 ,  A61P27/06

    摘要： Compounds that inhibit phosphodiesterase 1 (PDE1) are useful to treat glaucoma or elevated intraocular pressure. The PDE1 inhibitors may be administered as monotherapy or in combination with additional intraocular-pressure lowering agents. In addition, the invention provides ophthalmic compositions comprising PDE 1 inhibitors and optionally one or more additional intraocular pressure-lowering agents. Topical and systemic therapy may be used.

    CUSTOM MESSAGE PRESENTATION
    53.
    发明申请
    CUSTOM MESSAGE PRESENTATION 有权
    自定义消息呈现

    公开(公告)号：US20130246539A1

    公开(公告)日：2013-09-19

    申请号：US13420246

    申请日：2012-03-14

    申请人： Robert Davis

    发明人： Robert Davis

    IPC分类号： G06F15/16

    CPC分类号： G06Q30/0271 ,  G06Q30/0241 ,  G06Q30/0267

    摘要： For custom message presentation, an identification module identifies an optical code as not communication ready. A message module generates a custom message indexed to the optical code in response to identifying the optical code as not communication ready. The message module further makes the optical code communication ready in response to generating the custom message. In addition, the message module communicates the custom message in response to receiving the optical code and identifying the optical code as communication ready.

    摘要翻译： 对于自定义消息呈现，识别模块将光学代码识别为不通信就绪。 响应于将光学代码识别为不通信就绪，消息模块生成索引到光学代码的自定义消息。 响应于生成定制消息，消息模块进一步使得光学代码通信准备就绪。 此外，消息模块响应于接收到光学代码并将光学代码识别为通信就绪而传送定制消息。

    PDE1 INHIBITORS FOR OPHTHALMIC DISORDERS
    57.
    发明申请
    PDE1 INHIBITORS FOR OPHTHALMIC DISORDERS 审中-公开
    PDE1抑制性眼病

    公开(公告)号：US20110312978A1

    公开(公告)日：2011-12-22

    申请号：US13203365

    申请日：2010-02-24

    申请人： Robert Davis ,  Allen Fienberg

    发明人： Robert Davis ,  Allen Fienberg

    IPC分类号： A61K31/519 ,  A61P27/02 ,  A61P27/06 ,  C07D487/20 ,  C07D487/14

    CPC分类号： A61K31/535

    摘要： Compounds that inhibit phosphodiesterase 1 (PDE1) are useful to treat glaucoma or elevated intraocular pressure. The PDE1 inhibitors may be administered as monotherapy or in combination with additional intraocular-pressure lowering agents. In addition, the invention provides ophthalmic compositions comprising PDE 1 inhibitors and optionally one or more additional intraocular pressure-lowering agents. Topical and systemic therapy may be used.

    摘要翻译： 抑制磷酸二酯酶1（PDE1）的化合物可用于治疗青光眼或升高的眼内压。 PDE1抑制剂可以作为单一疗法或与额外的眼压降低剂组合施用。 此外，本发明提供了包含PDE 1抑制剂和任选的一种或多种另外的眼内压降剂的眼用组合物。 可以使用局部和全身治疗。

    Ice cream vending machine
    59.
    发明授权
    Ice cream vending machine 失效
    冰淇淋自动售货机

    公开(公告)号：US07448516B2

    公开(公告)日：2008-11-11

    申请号：US10869747

    申请日：2004-06-16

    申请人： Robert Davis ,  Otis Westerfield ,  Jorgen Bailey

    发明人： Robert Davis ,  Otis Westerfield ,  Jorgen Bailey

    IPC分类号： B67D5/62 ,  B67D5/10 ,  G07F13/00 ,  B65D35/28

    CPC分类号： G07F17/0071 ,  A23G9/281 ,  A23G9/283 ,  G07F11/10 ,  G07F13/025 ,  G07F13/06 ,  G07F13/10

    摘要： A soft serve ice cream vending machine is disclosed. The vending machine includes a machine cabinet; a door pivotably connected to he machine cabinet; the door including a cup dispensing slot and an ice cream dispensing slot; a product dispensing button connected to the door; a cup dispenser adapted to dispense a cup and connected to the door; a money acceptor connected to the door; a flexible product container connected to a freezer engine adapted to receive a product, the freezer engine having an outlet proximate to the ice cream dispensing slot; a venturi air valve connected to the freezer engine; a spigot control device connected to the freezer engine and to the product dispensing button, whereby upon engagement of the product dispensing button the spigot control device engages the freezer engine for a predetermined period of time.

    摘要翻译： 公开了一种软冰淇淋自动售货机。 自动售货机包括机柜; 门与机柜可枢转地连接; 门包括杯分配槽和冰淇淋分配槽; 连接到门的产品分配按钮; 适于分配杯子并连接到门的杯子分配器; 连接到门的货币接受者; 连接到适于接收产品的冷冻机引擎的柔性产品容器，所述冷冻机发动机具有靠近所述冰淇淋分配槽的出口; 连接到冷冻机发动机的文丘里空气阀; 连接到冷冻机引擎和产品分配按钮的插口控制装置，由此在产品分配按钮的接合时，插口控制装置接合冷冻机发动机预定的时间段。

    Automated instillation apparatus and method
    60.
    发明授权
    Automated instillation apparatus and method 有权
    自动滴灌装置及方法

    公开(公告)号：US07294120B1

    公开(公告)日：2007-11-13

    申请号：US10419325

    申请日：2003-04-18

    申请人： Jeff Brian Eidsen ,  Cindy Carol Eidsen ,  Bruno Mombrinie ,  Joe Peterson ,  Robert Davis

    发明人： Jeff Brian Eidsen ,  Cindy Carol Eidsen ,  Bruno Mombrinie ,  Joe Peterson ,  Robert Davis

    IPC分类号： A61M5/00

    CPC分类号： A61M3/0258 ,  A61M3/0216 ,  A61M2205/8206

    摘要： An automated instillation apparatus and method for instilling fluid into a patient having an intestinal stoma thereby administering an antegrade colonic enema. The automated instillation apparatus comprising in combination: a fluid reservoir, a pump, a pump control module, a fluid delivery line and an intestinal stoma catheter wherein the pump control module is operable to automatically stop fluid delivery to the intestinal stoma after a predetermined volume of fluid has been instilled at a predetermined flow rate and pressure range suitable for the particular patient. The automated instillation apparatus is optionally battery powered and of a size and weight suitable for carrying on a person. The automated instillation apparatus enables a method for a patient to self-administer an antegrade colonic enema within a short time period and with improved privacy by filling a fluid reservoir, inserting an intestinal stoma catheter into the patient with such a stoma opening and activating the apparatus to transfer fluid to the intestine without further intervention.

    摘要翻译： 一种自动滴注装置和方法，用于将流体灌注到具有肠口的患者中，从而施用顺行性结肠灌肠剂。 自动滴注装置组合包括：流体储存器，泵，泵控制模块，流体输送管线和肠造口导管，其中泵控制模块可操作以在预定体积的流体输送管线自动停止流体输送到肠口 流体已经以适合特定患者的预定流速和压力范围滴注。 自动滴注装置可选地是电池供电的，并且具有适合携带人的尺寸和重量。 自动滴注装置使得患者能够在短时间内自我施用顺行性结肠灌肠的方法，并且通过填充流体储存器来改善隐私，将肠造口导管插入到具有这种造口打开的患者体内并激活装置 将液体输送到肠道，无需进一步干预。