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    Drug delivery device, assembly for a drug delivery device and method for setting up a drug delivery device
    51.
    发明授权
    Drug delivery device, assembly for a drug delivery device and method for setting up a drug delivery device 有权
    药物递送装置，用于药物递送装置的组装和用于设置药物递送装置的方法

    公开(公告)号：US09555192B2

    公开(公告)日：2017-01-31

    申请号：US13497376

    申请日：2010-09-29

    申请人： Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Alexander Ian Bailey

    发明人： Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Alexander Ian Bailey

    IPC分类号： A61M5/00 ,  A61M5/24 ,  A61M5/31 ,  A61M5/315 ,  A61M5/20

    CPC分类号： A61M5/24 ,  A61M5/2448 ,  A61M5/3146 ,  A61M5/31571 ,  A61M5/31578 ,  A61M2005/2073 ,  A61M2005/2451

    摘要： The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member, an actuating member and a piston rod which is configured to act on a bung of an assembled cartridge containing the drug. In the pre-priming state the actuating member is configured to be moved by a user such that the movement of the actuating member causes a movement of the dose member and such that the movement of the dose member causes a movement of the piston rod. In the post-priming state the dose member is configured to be moved by a user without causing a movement of the actuating member in order to perform a set and dispense action of the drug delivery device.

    摘要翻译： 本申请涉及用于药物递送装置的组件，其被布置成以两种不同模式操作，从预灌注状态开始的启动模式和以后启动状态操作的分配模式，以及药物递送装置 包括该组件。 组件包括剂量构件，致动构件和活塞杆，其构造成作用在装有药物的组装好的药筒的栓上。 在预灌注状态下，致动构件被构造成由使用者移动，使得致动构件的移动导致剂量构件的运动，并且使得剂量构件的移动导致活塞杆的移动。 在后启动状态中，剂量构件被构造成由使用者移动而不引起致动构件的移动，以便执行药物递送装置的集合和分配动作。

    Drug Delivery Device
    53.
    发明申请
    Drug Delivery Device 审中-公开
    药物输送装置

    公开(公告)号：US20120310172A1

    公开(公告)日：2012-12-06

    申请号：US13498610

    申请日：2010-09-29

    申请人： Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay ,  Michael Bainton

    发明人： Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay ,  Michael Bainton

    IPC分类号： A61M5/31

    CPC分类号： A61M5/31525 ,  A61M5/31555 ,  A61M2005/2073

    摘要： A drug delivery device (10) is given, comprising a body (12) and a moveable button member (14), wherein in a pre-ready state of the drug delivery device (10) there is a misalignment between the body (12) and the button member (14). This misalignment is perceivable by a user of the drug delivery device (10). In a ready state of the drug delivery device (10), the button member (14) and the body (12) are aligned and the alignment is perceivable by a user of the drug delivery device (10).

    摘要翻译： 给药药物输送装置（10）包括主体（12）和可移动的按钮部件（14），其中在药物输送装置（10）的预准备状态下，主体（12）之间存在未对准 和按钮构件（14）。 药物输送装置（10）的使用者可以察觉到这种错位。 在药物递送装置（10）的准备状态下，按钮构件（14）和主体（12）对准，并且对准可由药物输送装置（10）的使用者察觉。

    Assembly for a Drug Delivery Device
    54.
    发明申请
    Assembly for a Drug Delivery Device 有权
    药物输送装置的装配

    公开(公告)号：US20120283653A1

    公开(公告)日：2012-11-08

    申请号：US13395701

    申请日：2010-09-29

    申请人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    发明人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    IPC分类号： A61M5/315

    CPC分类号： A61M5/24 ,  A61M5/3146 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/3156 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492

    摘要： A resettable drive mechanism for a drug delivery device (1) comprises a piston rod assembly (32) and an interaction member (23). The piston rod assembly (32) comprises a guide track (18) running along the piston rod assembly (32), the guide track (18) comprising at least one delivery section (18A) and at least one reset section (18B). The reset section (18B) is arranged to continue the delivery section (18A). The delivery section (18A) comprises at least one blocking means (19). The interaction member (23) is configured to cooperate with the guide track (18). For delivering a dose of a drug (24), the piston rod assembly (32) is axially displaceable in a dose delivery direction away from an axial starting position, the interaction member (23) cooperating with the delivery section (18A) and the blocking means (19) passing the interaction member (23) when the piston rod assembly (32) is displaced in the dose delivery direction. Axial displacement of the piston rod assembly (32) towards the axial starting position is prevented by mechanical interaction of the blocking means (19) and the interaction member (23) when the interaction member (23) cooperates with the delivery section (18A). For resetting the drug delivery device (1), the interaction member (23) is configured to cooperate with the reset section (18B), the piston rod assembly (32) being axially displaced towards the axial starting position, the blocking means (19) being offset from the interaction member (23) and passing the axial position of the interaction member (23) when the piston rod assembly (32) is axially displaced towards the axial starting position. Also, a piston rod assembly (32) is proposed.

    摘要翻译： 用于药物输送装置（1）的可重置驱动机构包括活塞杆组件（32）和相互作用构件（23）。 活塞杆组件（32）包括沿着活塞杆组件（32）延伸的导轨（18），导轨（18）包括至少一个输送部分（18A）和至少一个复位部分（18B）。 复位部分（18B）布置成继续传送部分（18A）。 输送部分（18A）包括至少一个阻挡装置（19）。 相互作用构件（23）构造成与导轨（18）配合。 为了递送药物（24）的剂量，活塞杆组件（32）可以在远离轴向起始位置的剂量递送方向上轴向移位，相互作用构件（23）与输送段（18A）配合并阻塞 当活塞杆组件（32）在剂量递送方向上移位时，装置（19）使相互作用构件（23）通过。 当相互作用构件（23）与输送段（18A）配合时，通过阻挡装置（19）和相互作用构件（23）的机械相互作用来防止活塞杆组件（32）朝向轴向起始位置的轴向位移。 为了复位药物输送装置（1），相互作用构件（23）构造成与复位部分（18B）配合，活塞杆组件（32）朝着轴向起始位置轴向移位，阻挡装置（19） 当所述活塞杆组件（32）朝向所述轴向起始位置轴向移位时，所述相互作用构件（23）偏离所述相互作用构件（23）的轴向位置。 此外，提出了一种活塞杆组件（32）。

    Pen-type injector
    57.
    发明申请
    Pen-type injector 有权
    笔式注射器

    公开(公告)号：US20050113765A1

    公开(公告)日：2005-05-26

    申请号：US10790025

    申请日：2004-03-02

    申请人： Robert Veasey ,  Christopher Langley ,  Steven Wimpenny

    发明人： Robert Veasey ,  Christopher Langley ,  Steven Wimpenny

    IPC分类号： A61M5/24 ,  A61M5/31 ,  A61M5/315 ,  A61M5/00

    CPC分类号： A61M5/31528 ,  A61M5/24 ,  A61M5/2422 ,  A61M5/31501 ,  A61M5/31511 ,  A61M5/31526 ,  A61M5/31533 ,  A61M5/31541 ,  A61M5/3155 ,  A61M5/31551 ,  A61M5/3156 ,  A61M5/31583 ,  A61M5/31585 ,  A61M5/31593 ,  A61M2205/581 ,  A61M2205/582

    摘要： The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a cartridge containing medicinal product, the cartridge being retained within the housing, means for selecting a dose of medicinal product to be expelled, and means for expelling the selected dose of medicinal product. The housing may be a unitary housing within which the means for selecting a dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.

    摘要翻译： 本发明涉及一种注射器，例如笔式注射器，其提供从多剂量药筒施用药用产品并允许使用者设​​定递送剂量。 注射器可以包括壳体，包含医药产品的药筒，保持在壳体内的药筒，用于选择要排出的药物产品的剂量的装置，以及用于排出所选剂量的药品的装置。 外壳可以是整体式的外壳，用于选择剂量的装置和用于排出所选剂量的装置可移动地保持在其中。 或者，注射器可以包括壳体，活塞杆，位于壳体中并且活塞可以旋转的插入件，棘轮装置，剂量拨片套筒，驱动套筒，位于驱动套筒上的按钮，并且可相对于 驱动套筒和离合器装置，其在按下按钮时防止剂量拨号套筒和驱动套筒之间的旋转。

    Medicament delivery device
    58.
    发明申请
    Medicament delivery device 审中-公开
    药物输送装置

    公开(公告)号：US20050075608A1

    公开(公告)日：2005-04-07

    申请号：US10375098

    申请日：2003-02-28

    申请人： James Holdgate ,  Robert Veasey ,  Christopher Langley

    发明人： James Holdgate ,  Robert Veasey ,  Christopher Langley

    IPC分类号： A61M5/24 ,  A61M1/00

    CPC分类号： A61M5/24 ,  A61M2005/2407 ,  A61M2005/2496

    摘要： An actuator is provided which is adapted, in conjunction with a cartridge, to form a needle-less injector, the cartridge being filled with a liquid to be injected in a subject, and having a liquid outlet and a free piston in contact with the liquid. The actuator comprises an impact member urged by a spring and temporarily restrained by a latch, the impact member being movable in a first direction under the force of the spring to first strike the free piston and then to continue to move the piston in the first direction to expel a dose of liquid through the liquid outlet, the spring providing a built-in energy store. A pressure pad surrounds the said liquid outlet and, in use, bears on the subject's skin. The actuator may be formed of two main housing components urged apart by an integral cantilever spring formed on one of them, a safety catch can be provided to prevent inadvertent actuation.

    摘要翻译： 提供致动器，该致动器与筒结合使用以形成无针注射器，该药筒充满待注射到被检体内的液体，并具有液体出口和与液体接触的自由活塞 。 致动器包括由弹簧推动并由闩锁暂时约束的冲击构件，冲击构件可在弹簧的作用力下沿第一方向移动以首先冲击自由活塞，然后继续沿第一方向移动活塞 通过液体出口排出一定剂量的液体，弹簧提供内置的能量储存器。 压力垫围绕所述液体出口并且在使用中承载在受试者的皮肤上。 致动器可以由两个主壳体部件形成，两个主壳体部件由形成在其中一个上的整体悬臂弹簧推动分开，可以提供安全锁止件以防止意外致动。

    Drive mechanism for a drug delivery device
    59.
    发明授权
    Drive mechanism for a drug delivery device 有权
    药物输送装置的驱动机构

    公开(公告)号：US09375535B2

    公开(公告)日：2016-06-28

    申请号：US13497378

    申请日：2010-09-29

    申请人： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

    发明人： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

    IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/31

    CPC分类号： A61M5/3158 ,  A61M5/24 ,  A61M5/31541 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/31556 ,  A61M2005/2407 ,  A61M2005/2477 ,  A61M2005/3126

    摘要： According to one aspect, a resettable drive assembly for a drug delivery device is provided for. The resettable drive assembly may comprise a housing having a proximal end and a distal end, a piston rod being rotatable with respect to the housing and being axially displaceable with respect to the housing between a proximal start position and a distal end position, a drive member for distally displacing the piston rod towards the end position when dispensing a dose, and a stop member. The drive assembly may be configured such that the drive member is operable to interact with the piston rod for forming an unlockable first interlock, the first interlock being operable to block proximal movement of the piston rod with respect to the drive member. The drive assembly may be configured such that the stop member is operable to interact with the piston rod for forming an unlockable second interlock, the second interlock being operable to block proximal movement of the piston rod with respect to the housing. The drive assembly may be configured such that, when the drive assembly is in a drive mode, the first and second interlocks are locked such that proximal movement of the piston rod from the end position to the start position is prevented by the first interlock and the second interlock. The drive assembly may be configured such that, for switching the drive assembly from the drive mode to a reset mode, the piston rod is rotatable with respect to the drive member for unlocking the first interlock and the stop member and the piston rod are rotatable with respect to each other for unlocking the second interlock. The drive assembly may be configured such that, when the drive assembly is in the reset mode, the first interlock and the second interlock are unlocked such that proximal movement of the piston rod to the start position is allowed. Further, a drug delivery device and a use of a spring are provided for.

    摘要翻译： 根据一个方面，提供了一种用于药物递送装置的可重置驱动组件。 可重置驱动组件可以包括具有近端和远端的壳体，活塞杆可相对于壳体旋转并且能够在近端起始位置和远端位置之间相对于壳体轴向移动，驱动构件 用于在分配剂量时将活塞杆朝向终端位置移动，以及止挡构件。 驱动组件可以构造成使得驱动构件可操作以与活塞杆相互作用以形成可解锁的第一互锁，第一互锁可操作以阻止活塞杆相对于驱动构件的近端运动。 驱动组件可以被配置为使得止动构件可操作以与活塞杆相互作用以形成可解锁的第二互锁，所述第二互锁可操作以阻止活塞杆相对于壳体的近端运动。 驱动组件可以构造成使得当驱动组件处于驱动模式时，第一和第二互锁被锁定，使得活塞杆从终端位置到起始位置的近端运动通过第一互锁来防止，并且 第二个互锁。 驱动组件可以被配置成使得为了将驱动组件从驱动模式切换到复位模式，活塞杆可相对于驱动构件旋转，用于解锁第一联锁装置，止动构件和活塞杆可随着 彼此相对以解锁第二互锁。 驱动组件可以被构造成使得当驱动组件处于复位模式时，第一互锁和第二联锁被解锁，使得允许活塞杆的近端运动到起始位置。 此外，提供了药物递送装置和弹簧的使用。

    Assembly of a drug delivery device
    60.
    发明授权
    Assembly of a drug delivery device 有权
    组装药物输送装置

    公开(公告)号：US09265891B2

    公开(公告)日：2016-02-23

    申请号：US13395840

    申请日：2010-09-29

    申请人： Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay ,  Michael Bainton

    发明人： Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay ,  Michael Bainton

    IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/20

    CPC分类号： A61M5/3155 ,  A61M2005/2073

    摘要： An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.

    摘要翻译： 给出了具有纵向轴线（L）的药物递送装置的组件，包括具有近端（2）和远端（3）的主体（1）。 药物输送装置还包括驱动组件和第一按钮构件（4）。 驱动组件至少部分地布置在主体（1）内，并且适于便于分配药物。 第一按钮构件（4）作用在驱动组件上以制备用于分配药物的药物输送装置。 第一按钮构件（4）适于在药物输送装置的制备完成之后与主体（1）分离。