公开(公告)号：US11278409B2

公开(公告)日：2022-03-22

申请号：US16290572

申请日：2019-03-01

Applicant: Edwards Lifesciences Corporation

Inventor： Alex Philip McCann ,  Grant Matthew Stearns ,  Eric Robert Dixon ,  Yoon Hee Kwon

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34

Abstract: A method of manufacturing a valve repair device for repairing a native valve of a patient includes: folding a strip of material formed from shape-memory alloy around a jig to form a coaption element and a pair of paddles connected to the coaption element, wherein the paddles are movable between an open position and a closed position and are configured to attach to the native valve of the patient; and heat treating the strip of material to shape-set the strip of material in the shape of the coaption element and paddles.

公开(公告)号：US20220071767A1

公开(公告)日：2022-03-10

申请号：US17526581

申请日：2021-11-15

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Asher L. Metchik ,  Rachel Ann Gohres ,  Tam Van Nguyen ,  Grant Matthew Stearns ,  Gregory Scott Tyler, II ,  Daniel James Montoya ,  Rhayoung Kwon ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: A method and system for implanting and repositioning an implantable device for a native valve of a patient's heart includes a delivery catheter, a collar, a coupler, and an actuation element. The actuation element extends through the delivery catheter and attaches to the device to open the device. The collar is connected to the device and the coupler is connected to the delivery catheter. The collar and coupler are tied together via one or more coupling tethers which can be used to reengage the device after an initial deployment.

公开(公告)号：US11083581B2

公开(公告)日：2021-08-10

申请号：US16208264

申请日：2018-12-03

Applicant: Edwards Lifesciences Corporation

Inventor： Grant Matthew Stearns ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: In one embodiment, an expandable positioning device for improving the coaptation of heart valve leaflets is provided. The expandable positioning device can include one or more expandable members. A first expandable member extends below a leaflet in order to reposition the leaflet to improve coaptation with another leaflet. A second expandable member extends above a leaflet in order to secure the expandable delivery device at the implantation site. The expandable positioning device can include a neck that is inserted through the leaflet on which the device is implanted. The expandable positioning device can include a coupling member to releasably couple the device to a delivery device. One or more sealing members can be included in the expandable positioning device to maintain a desired level of expansion of the one or more expandable members.

公开(公告)号：US10987221B2

公开(公告)日：2021-04-27

申请号：US16207693

申请日：2018-12-03

Applicant: Edwards Lifesciences Corporation

Inventor： Alex Philip McCann ,  Grant Matthew Stearns ,  Eric Robert Dixon ,  Yoon Hee Kwon

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34

Abstract: An exemplary valve repair device for repairing a native valve of a patient includes: a collar; a coaption element attached to the collar; and a pair of paddles are connected to the coaption element. The collar has a plurality of engagement portions configured to releasably engage a delivery apparatus. The paddles are movable between an open position and a closed position and are configured to attach to the native valve of the patient. The paddles are circumferentially disposed between the engagement portions.

公开(公告)号：US20200237512A1

公开(公告)日：2020-07-30

申请号：US16847577

申请日：2020-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Alex Philip McCann ,  Grant Matthew Stearns ,  Eric Robert Dixon ,  Yoon Hee Kwon ,  Michael J. Popp ,  Sergio Delgado ,  Lauren R. Freschauf ,  Rachel Ann Gohres ,  Rachel Liat David Foreman

IPC: A61F2/24

Abstract: An implantable prosthetic device has a coaption element and at least one anchor. The coaption element is configured to be positioned within the native heart valve orifice to help fill a space where the native valve is regurgitant and form a more effective seal. The coaption element can have a structure that is impervious to blood. The coaption element can be connected to leaflets of the native valve by the anchor.

公开(公告)号：US20190290434A1

公开(公告)日：2019-09-26

申请号：US16293306

申请日：2019-03-05

Applicant: Edwards Lifesciences Corporation

Inventor： Grant Matthew Stearns ,  Gregory Bak-Boychuk ,  Sergio Delgado

IPC: A61F2/24 ,  A61F2/86

Abstract: A coronary artery check valve includes a stent configured to attach to an inner wall of a coronary artery of a living subject, and a tapered helical coil coupled to the stent and configured to regulate blood flow in the coronary artery. The coronary artery check valve is configured to prevent retrograde flow of the coronary blood supply during diastole by closing during systole of the heart when the tapered helical coil compresses longitudinally, and opening when the tapered helical coil expands longitudinally to permit blood flow into the coronary artery when a coronary pressure of the living subject drops below diastolic blood pressure.

公开(公告)号：US20190069993A1

公开(公告)日：2019-03-07

申请号：US16179591

申请日：2018-11-02

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Sirous Darabian ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: An exemplary valve repair system for repairing a native valve of a patient during a non-open-heart procedure has a delivery device and a valve repair device. The valve repair device is configured to be delivered through a lumen of the delivery device and to attach to a native valve of a patient. The valve repair device has first and second paddles and first and second gripping members. The first and second paddles are movable between an open position and a closed position. The first gripping member is attached to the first paddle and the second gripping member is attached to the second paddle. The gripping members are configured to attach to the native valve of the patient. A gripper control mechanism is configured to separately move the first and second gripping members.

公开(公告)号：US20190021851A1

公开(公告)日：2019-01-24

申请号：US16138728

申请日：2018-09-21

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Sirous Darabian ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: An exemplary valve repair device for repairing a native valve of a patient has a paddle frame, and inner and outer paddle portions formed from a strip of metal fabric. The paddle frame has a round three-dimensional shape. The strip of metal fabric is attached to a closed attachment portion of the paddle frame.

公开(公告)号：US20190015208A1

公开(公告)日：2019-01-17

申请号：US16135920

申请日：2018-09-19

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Sirous Darabian ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34

Abstract: In an exemplary method of implanting a valve repair device on a mitral valve of a patient, first and second clasps of the valve repair device are closed to grasp the leaflets of the mitral valve. First and second paddles of the valve repair device are closed to bring the leaflets of the mitral valve into contact with a coaption element.

公开(公告)号：US20180325661A1

公开(公告)日：2018-11-15

申请号：US15973892

申请日：2018-05-08

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Devin H. Marr ,  Tam Van Nguyen ,  Rhayoung Kwon ,  Victoria Cheng-Tan Wu

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075

Abstract: An implantable prosthetic device can include a spacer member, a plurality of anchors, and a plurality of clasps. The spacer member can be configured to be disposed between native leaflets of a heart. The anchors can be coupled to the spacer member and configured to secure the native leaflets against the spacer member. The clasps can be coupled to a respective anchor and configured to secure the native leaflets to the anchors. The clasps can be independently movable between an open configuration and a closed configuration.