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公开(公告)号：US20240335287A1
公开(公告)日：2024-10-10
申请号：US18745063
申请日：2024-06-17
发明人： Mark Chau , Travis Zenyo Oba , Sam Shafigh , Jean-Pierre Michel Rabbah , David M. Taylor , Philippe Marchand , Madison Paige Kukura , Cristobal R. Hernandez , Nancy Hoang Khuu , Florian Georg Deuschl , Biswa P. Das , Andrew Charles May , Bhumica A. Amin
IPC分类号： A61F2/24
CPC分类号： A61F2/2463 , A61F2/2466 , A61F2220/0008 , A61F2230/0008
摘要： Systems and methods are disclosed for use with a valve of a heart. An implant (100) includes a wing (120); a flexible frame (124); and a pair of anchor receivers (150). A pair of shafts (660) are transluminally advanced through a catheter (40), while the shafts are each engaged with a respective anchor receiver (150), to deploy the implant out of the catheter such that the wing extends away from the anchor receivers and over a first leaflet of the valve and toward an opposing leaflet of the valve, with a contact face (122) of the wing facing the first leaflet. A pair of drivers (70) secure the implant using a pair of anchors (30) to anchor each anchor receiver to tissue at respective sites of the heart. Other implementations are also described.
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公开(公告)号：US20240299163A1
公开(公告)日：2024-09-12
申请号：US18658829
申请日：2024-05-08
发明人： Taylor Jacob Scheinblum , Hieu Minh Luong , David Robert Landon , Siddharth Vad , Ramon Aguilar, JR. , David M. Taylor , Jesse Robert Edwards , Brandon Sina Dehdashtian
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2220/0008
摘要： Devices, systems, and methods relate to implants, such as prosthetic valves for replacing native heart valves. Delivery systems for delivering the implants to an implantation site are also disclosed herein. A prosthetic valve may include a valve body supporting a plurality of prosthetic valve leaflets and one or more adjustable anchors coupled to the valve body for anchoring the prosthetic valve to leaflets of a native heart valve, wherein at least one of the adjustable anchors is axially slidable relative to the valve body for conforming to the native anatomy of the native heart valve.
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公开(公告)号：US11850153B2
公开(公告)日：2023-12-26
申请号：US17178162
申请日：2021-02-17
CPC分类号： A61F2/246 , A61B17/00 , A61B17/00234 , A61B17/0469 , A61B17/3468 , A61F2/24 , A61F2/243 , A61F2/2409 , A61F2/2418 , A61F2/2442 , A61F2/2445 , A61F2/2457 , A61L27/04 , A61B17/0057 , A61B17/0401 , A61B2017/00243 , A61B2017/00557 , A61B2017/00783 , A61B2017/00867 , A61B2017/0464 , A61F2/2427 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2210/009 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0041 , A61F2220/0075 , A61F2220/0091 , A61F2230/0004 , A61F2230/0008 , A61F2230/0013 , A61F2230/0045 , A61F2230/0069 , A61F2230/0093 , A61F2240/00 , A61F2250/006 , A61F2250/0036 , A61F2250/0069
摘要： A valve repair devices and systems for repairing a native valve of a patient include a spacer, a pair of paddles, and a pair of moveable clasp arms. The pair of moveable clasp arms are disposed between the pair of paddles and the spacer. The moveable clasp arms are configured to attach to leaflets of a heart valve. The spacer, the pair of paddles, and the moveable clasp arms are configured such that, when attached to the leaflets, the moveable clasp arms are located between the spacer and first portions of the leaflet, while second portions of the leaflet engage the spacer.
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公开(公告)号：US11793642B2
公开(公告)日：2023-10-24
申请号：US16522600
申请日：2019-07-25
发明人： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
摘要： In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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公开(公告)号：US20230190460A1
公开(公告)日：2023-06-22
申请号：US18166797
申请日：2023-02-09
发明人： David M. Taylor , Alexander J. Siegel , Thomas V. Doherty , Christopher J. Olson , Yoon Hee Kwon
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2463 , A61F2/2412 , A61L27/18
摘要： Embodiments of the present disclosure include an implantable assembly for a native heart valve that includes a prosthetic heart valve and a braided support structure. The prosthetic valve includes a frame and prosthetic leaflets. The braided support structure has an inner braided layer and an outer braided layer. The outer braided layer is disposed over the inner braided layer. The outer braided layer is less porous to blood than the inner braided layer. The braided support structure defines a plurality of arms that are angularly spaced around the prosthetic heart valve such that each arm extends radially outwardly from the prosthetic heart valve. Other embodiments are also described.
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公开(公告)号：US11602431B2
公开(公告)日：2023-03-14
申请号：US16171202
申请日：2018-10-25
发明人： Sergio Delgado , Eric Robert Dixon , David M. Taylor , Asher L. Metchik , Matthew T. Winston , Gregory Scott Tyler, II , Lauren R. Freschauf , Alexander J. Siegel
摘要： An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.
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公开(公告)号：US10849754B2
公开(公告)日：2020-12-01
申请号：US16130853
申请日：2018-09-13
摘要： An exemplary implantable prosthetic device has a coaption element and a pair of paddles. The coaption element has a first end portion and a second end portion. The pair of paddles is connected to the second end portion of the coaption element. The coaption element narrows as the copation element extends from the first end portion to the second end portion. The paddles are movable between an open position and a closed position. The paddles are configured to attach to the native valve of the patient.
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公开(公告)号：US20200246136A1
公开(公告)日：2020-08-06
申请号：US16842837
申请日：2020-04-08
发明人： Devin H. Marr , Sergio Delgado , Eric Robert Dixon , David M. Taylor , Asher L. Metchik , Matthew T. Winston
IPC分类号： A61F2/24 , A61B17/128 , A61B17/122
摘要： A delivery system includes an elongate shaft, a handle, a first clasp control member, and a second clasp control member. The handle is connected to a proximal portion of the elongate shaft. The first and second clasp control members each extend into a distal portion of the elongate shaft, through at least a portion of the elongate shaft, out of the proximal portion of the elongate shaft, and through the handle. The first and second clasp control members have paths that include a first parallel portion in the elongate shaft where the first clasp control member and the second clasp control member are parallel, and a diverging portion that is proximal to the first parallel portion where the first clasp control member diverges from the second clasp control member.
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公开(公告)号：US20200237504A1
公开(公告)日：2020-07-30
申请号：US16849243
申请日：2020-04-15
发明人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , David J. Evans , Rajesh A. Khanna
IPC分类号： A61F2/24
摘要： A valve catheter is advanced through a patient's vasculature while a prosthetic heart valve is attached to flexible extensions along a distal end thereof. The valve catheter is advanced through a tubular sleeve for exposing the prosthetic heart valve and allowing the prosthetic heart valve to self-expand while the extensions remain attached to the prosthetic heart valve. A release mechanism on a handle portion is actuated for releasing the prosthetic heart valve from the extensions, thereby implanting the prosthetic heart in a native heart valve. If the operator is not satisfied with the initial expansion, the prosthetic heart valve may be reoriented before release from the extensions by retracting the prosthetic heart valve back into the tubular sleeve, adjusting the orientation of the prosthetic heart valve and then re-advancing the valve catheter from the tubular sleeve for allowing the prosthetic heart valve to re-self-expand at a more desirable location.
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公开(公告)号：US20200155310A1
公开(公告)日：2020-05-21
申请号：US16709806
申请日：2019-12-10
发明人： David M. Taylor
IPC分类号： A61F2/24
摘要： An assembly for delivering a prosthetic heart valve to a native heart valve is disclosed. The assembly includes a self-expanding prosthetic heart valve formed with an expandable metallic stent and a flexible valvular structure. The assembly also includes a delivery apparatus having a delivery sleeve. The delivery sleeve includes a selectively steerable section and a distal portion for retaining the prosthetic heart valve in a compressed state. A handle is coupled to a proximal end of the delivery sleeve and a pull wire extends from the handle to the steerable section of the delivery sleeve. The handle preferably includes a rotatable portion for actuating the pull wire and thereby selectively controlling a curvature of the steerable section during advancement through the patient's vasculature. In preferred embodiments, the steerable section includes a flexible metallic tubular portion formed with a plurality of circumferentially extending openings.
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