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51.
公开(公告)号:US20150167018A1
公开(公告)日:2015-06-18
申请号:US14403651
申请日:2013-05-28
Applicant: GenVec, Inc.
Inventor: Lisa Wei , Douglas E. Brough , C. Richter King
CPC classification number: C12N15/86 , A61K48/00 , A61K48/0008 , C12N2710/10021 , C12N2710/10043 , C12N2710/10322 , C12N2710/10343 , C12N2710/10345 , C12N2710/16634 , C12N2810/6018
Abstract: The invention provides a replication-deficient serotype 28 adenoviral vector characterized by comprising a portion of a serotype 45 adenoviral hexon protein and/or a portion of a serotype 45 fiber protein in place of the endogenous serotype 28 hexon and/or fiber protein.
Abstract translation: 本发明提供了一种复制缺陷型血清型28腺病毒载体,其特征在于包含部分血清型45腺病毒六邻体蛋白和/或血清型45纤维蛋白的一部分代替内源性血清型28六邻体和/或纤维蛋白。