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    Novel imidazoline compounds
    51.
    发明申请
    Novel imidazoline compounds 失效
    新型咪唑啉化合物

    公开(公告)号：US20060135559A1

    公开(公告)日：2006-06-22

    申请号：US11348459

    申请日：2006-02-07

    申请人： Nagaaki Sato ,  Osamu Okamoto ,  Makoto Jitsuoka ,  Keita Nagai ,  Akio Kanatani ,  Akane Ishihara ,  Yasuyuki Ishii ,  Takehiro Fukami

    发明人： Nagaaki Sato ,  Osamu Okamoto ,  Makoto Jitsuoka ,  Keita Nagai ,  Akio Kanatani ,  Akane Ishihara ,  Yasuyuki Ishii ,  Takehiro Fukami

    IPC分类号： A61K31/4709 ,  A61K31/4439 ,  A61K31/4178 ,  C07D409/02 ,  C07D403/02

    CPC分类号： C07D401/04 ,  C07D233/26 ,  C07D401/14 ,  C07D403/04 ,  C07D417/04 ,  C07D417/14 ,  C07D471/04

    摘要： Compounds represented by the general formula (I): wherein Ar1 and Ar2 are each aryl or heteroaryl; R1 is lower cycloalkyl, —Ar3, or a group of the general formula (a), (b) or (c): and R2 and R3are each hydrogen, lower cycloalkyl, lower alkenyl, or optionally substituted lower alkyl (with the proviso that when R2 and R3 are simultaneously hydrogen, Ar1, Ar2 and R1 do not simultaneously represent unsubstituted phenyl). The compounds are useful as treating agents for various NPY-related diseases, for example, circulatory diseases including hypertension, kidney diseases, cardiac diseases, vasospasm and arteriosclerosis; central nervous system diseases including hyperphagia, depression, anxiety, convulsion, epilepsy, dementia, pain, alcohol dependence, and withdrawal symptoms due to abstinence from drugs; metabolic diseases including obesity, diabetes, hormonal disorders, hypercholesterolemia, and hyperlipidemia; sexual dysfunction and reproductive function disorders; digestive diseases including enterokinetic disorders; respiratory diseases; inflammation; or glaucoma.

    摘要翻译： 由通式（I）表示的化合物：其中Ar 1和Ar 2各自为芳基或杂芳基; R 1是低级环烷基，-Ar 3或通式（a），（b）或（c）的基团：R 2， R 3和R 3各自为氢，低级环烷基，低级烯基或任选取代的低级烷基（条件是当R 2和R 3' / SUP>同时为氢，Ar 1，Ar 2和R 1不同时表示未取代的苯基）。 这些化合物可用作各种NPY相关疾病的治疗剂，例如包括高血压，肾脏疾病，心脏病，血管痉挛和动脉硬化的循环系统疾病; 中枢神经系统疾病，包括食欲过多，抑郁，焦虑，惊厥，癫痫，痴呆，疼痛，酒精依赖以及戒毒症状; 代谢疾病包括肥胖，糖尿病，激素失调，高胆固醇血症和高脂血症; 性功能障碍和生殖功能障碍; 消化疾病包括肠动力障碍; 呼吸疾病; 炎; 或青光眼。

    Imidazonline compounds
    52.
    发明授权
    Imidazonline compounds 失效
    咪唑啉化合物

    公开(公告)号：US07064142B2

    公开(公告)日：2006-06-20

    申请号：US10204267

    申请日：2001-02-22

    申请人： Nagaaki Sato ,  Osamu Okamoto ,  Makoto Jitsuoka ,  Keita Nagai ,  Akio Kanatani ,  Akane Ishihara ,  Yasuyuki Ishii ,  Takehiro Fukami

    发明人： Nagaaki Sato ,  Osamu Okamoto ,  Makoto Jitsuoka ,  Keita Nagai ,  Akio Kanatani ,  Akane Ishihara ,  Yasuyuki Ishii ,  Takehiro Fukami

    IPC分类号： A61K31/415 ,  C07D233/26

    CPC分类号： C07D401/04 ,  C07D233/26 ,  C07D401/14 ,  C07D403/04 ,  C07D417/04 ,  C07D417/14 ,  C07D471/04

    摘要： Compounds represented by the general formula (I): wherein Ar1 and Ar2 are each aryl or heteroaryl; R1 is lower cycloalkyl, —Ar3, or a group of the general formula (a), (b) or (c): and R2 and R3 are each hydrogen, lower cycloalkyl, lower alkenyl, or optionally substituted lower alkyl (with the proviso that when R2 and R3 are simultaneously hydrogen, Ar1, Ar2 and R1 do not simultaneously represent unsubstituted phenyl). The compounds are useful as treating agents for various NPY-related diseases, for example, circulatory diseases including hypertension, kidney diseases, cardiac diseases, vasospasm and arteriosclerosis; central nervous system diseases including hyperphagia, depression, anxiety, convulsion, epilepsy, dementia, pain, alcohol dependence, and withdrawal symptoms due to abstinence from drugs; metabolic diseases including obesity, diabetes, hormonal disorders, hypercholesterolemia, and hyperlipidemia; sexual dysfunction and reproductive function disorders; digestive diseases including enterokinetic disorders; respiratory diseases; inflammation; or glaucoma.

    摘要翻译： 由通式（I）表示的化合物：其中Ar 1和Ar 2各自为芳基或杂芳基; R 1是低级环烷基，-Ar 3或通式（a），（b）或（c）的基团：R 2， R 3和R 3各自为氢，低级环烷基，低级烯基或任选取代的低级烷基（条件是当R 2和R 3' / SUP>同时为氢，Ar 1，Ar 2和R 1不同时表示未取代的苯基）。 这些化合物可用作各种NPY相关疾病的治疗剂，例如包括高血压，肾脏疾病，心脏病，血管痉挛和动脉硬化的循环系统疾病; 中枢神经系统疾病，包括食欲过多，抑郁，焦虑，惊厥，癫痫，痴呆，疼痛，酒精依赖以及戒毒症状; 代谢疾病包括肥胖，糖尿病，激素失调，高胆固醇血症和高脂血症; 性功能障碍和生殖功能障碍; 消化疾病包括肠动力障碍; 呼吸疾病; 炎; 或青光眼。

    Combined engine for single-stage spacecraft
    53.
    发明申请
    Combined engine for single-stage spacecraft 失效
    单级飞船组合发动机

    公开(公告)号：US20050016157A1

    公开(公告)日：2005-01-27

    申请号：US10623601

    申请日：2003-07-22

    申请人： Osamu Okamoto ,  Tatsuo Yamanaka ,  Masataka Maita ,  Hideyuki Taguchi ,  Takeshi Tsuchiya

    发明人： Osamu Okamoto ,  Tatsuo Yamanaka ,  Masataka Maita ,  Hideyuki Taguchi ,  Takeshi Tsuchiya

    IPC分类号： B64C30/00 ,  B64G1/14 ,  B64G1/40 ,  F02K7/18

    CPC分类号： B64G1/402 ,  B64C30/00 ,  B64G1/14 ,  B64G1/401 ,  F02K7/18

    摘要： A novel combined engine for a single-stage spacecraft is provided that combines a air-breathing engine utilizing oxygen in the atmosphere as oxidizer and rocket engines for obtaining thrust outside the atmosphere and that does not require a portion whose shape is variable in accordance with the flight speed. Rocket engines 15 are provided on struts 12 that form air introduction channels 10 in the air intake section 4. The rocket jets 18 from the rocket engines 15 control the flow of the airflows 16 introduced into the combustion chamber 20 in accordance with the flight speed. When the spacecraft 1 is stationary or in subsonic flight, the rocket jets 18 promote air intake into the combustion chamber 20 by lowering of static pressure due to expansion (ejector effect). In the subsonic flight condition, it performs the role of air compression, mixing with incoming air, fuel injection and ignition and during supersonic/ultra-supersonic flight it performs the role of a variable diffuser.

    摘要翻译： 提供了一种用于单级航天器的新型组合发动机，其将在大气中使用氧气的空气呼吸发动机作为氧化剂和用于在大气外部获得推力的火箭发动机相结合，并且不需要其形状根据 飞行速度。 火箭发动机15设置在支柱12上，支柱12在空气吸入部分4中形成空气引入通道10.来自火箭发动机15的火箭喷射器18根据飞行速度控制引入燃烧室20的气流16的流动。 当航天器1是静止或亚音速飞行时，火箭喷射器18通过由于膨胀（喷射器效应）降低静压而促进进入燃烧室20的空气。 在亚音速飞行条件下，它起到空气压缩，与进入的空气混合，燃料喷射和点燃的作用，并且在超音速/超超音速飞行期间，它执行可变扩散器的作用。

    Multidimensional damping apparatus
    55.
    发明授权
    Multidimensional damping apparatus 失效
    多维阻尼装置

    公开(公告)号：US5248133A

    公开(公告)日：1993-09-28

    申请号：US859813

    申请日：1992-03-30

    申请人： Osamu Okamoto ,  Teruomi Nakaya ,  Seizo Suzuki ,  Naoaki Kuwano ,  Kenji Ogimoto ,  Ryuji Sakata ,  Yasuaki Taniguchi ,  Hiroyoshi Tanaka ,  Goji Iba

    发明人： Osamu Okamoto ,  Teruomi Nakaya ,  Seizo Suzuki ,  Naoaki Kuwano ,  Kenji Ogimoto ,  Ryuji Sakata ,  Yasuaki Taniguchi ,  Hiroyoshi Tanaka ,  Goji Iba

    IPC分类号： F16F6/00 ,  F16F7/00 ,  F16F15/00 ,  F16F15/03 ,  F16F15/10 ,  F16L3/20 ,  F16L3/215

    CPC分类号： F16F15/10 ,  F16F15/03

    摘要： A plurality of eccentric rotors are rotatably fitted between a fixed base and an output shaft on which an object to be vibrationproofed is mounted, the output shaft being supported movably in 3 to 6 Degree-of-Freedom, magnet spring mechanisms are provided on fitted wall surfaces between the fixed base and the eccentric rotor, a composite vibrationproof adjusting spring is provided between the fixed base and the output shaft, the magnet spring mechanism responding to a fine displacement of the output shaft, and in a case where the output shaft is greatly displaced, the output shaft is braked so as to be restored to a predetermined position by the composite vibrationproof adjusting spring mechanism. The magnet spring mechanism produces a large braking force since a rotational angle is large and a rotational-angle speed is high due to eccentricity of eccentric rotors.

    摘要翻译： 多个偏心转子可旋转地装配在固定基座和安装有防振物体的输出轴之间，输出轴以3至6自由度可动地支撑，弹簧机构设置在安装壁上 在固定基座和偏心转子之间的表面，在固定基座和输出轴之间设置复合防振调节弹簧，弹簧机构响应于输出轴的精细位移，并且在输出轴大大的情况下 输出轴被制动，以便通过复合防振调节弹簧机构恢复到预定位置。 磁簧弹簧机构产生大的制动力，因为由于偏心转子的偏心，旋转角度大，转角速度高。

    Control method and apparatus therefor
    56.
    发明授权
    Control method and apparatus therefor 失效
    控制方法及装置

    公开(公告)号：US5043917A

    公开(公告)日：1991-08-27

    申请号：US362132

    申请日：1989-06-06

    申请人： Osamu Okamoto

    发明人： Osamu Okamoto

    IPC分类号： G02F1/133 ,  G09G3/36

    CPC分类号： G09G3/3607

    摘要： Bit map memories, which have addresses corresponding to orderly-arranged red, green and blue dots of a color display panel, are provided corresponding to red, green and blue colors, respectively, and a color array memory is provided which has prestored data indicating the array of the colors of the dots in at least one dot area of the color display panel. Bit map data are simultaneously read out of the three bit map memories in the order of arrangement of the dots of the color display panel, and the bit map data thus read out are input into a color selector. In synchronization with this data readout color array data is read out of the color array memory. The color array data thus read out is used to control the color selector to output therefrom, as a color display control signal, the bit map data of a specified color.

    摘要翻译： 分别对应于红色，绿色和蓝色对应于彩色显示面板的有序布置的红色，绿色和蓝色点的地址的位图存储器，并且提供了一种颜色阵列存储器，其具有指示 在彩色显示面板的至少一个点区域中的点的颜色的阵列。 按照彩色显示面板的点排列顺序从3位图存储器中同时读出位图数据，并将由此读出的位图数据输入到颜色选择器中。 与该数据读出同步，颜色阵列数据从彩色阵列存储器读出。 这样读出的颜色阵列数据用于控制颜色选择器作为彩色显示控制信号输出指定颜色的位图数据。