公开(公告)号：US08321028B1

公开(公告)日：2012-11-27

申请号：US12326804

申请日：2008-12-02

申请人： Chuladatta Thenuwara ,  William A. Morgan ,  Janusz A. Kuzma

发明人： Chuladatta Thenuwara ,  William A. Morgan ,  Janusz A. Kuzma

IPC分类号： A61N1/00

CPC分类号： A61N1/37229 ,  A61N1/36036

摘要： An impact resistant implantable antenna coil assembly comprising a flat antenna coil having a plurality of laterally separated turns of wire encapsulated with a non-orthogonal force absorbing coil reinforcement in a flexible biocompatible polymer and axially anchored with the reinforcement to a feedthrough case. Thus configured, non-orthogonal impact forces applied to the antenna coil assembly are absorbed and lateral components thereof that would otherwise be reflected as tensile forces in the plane of the coil are prevented from forming or from fracturing wire within the antenna coil.

摘要翻译： 一种耐冲击植入式天线线圈组件，其包括平面天线线圈，该平面天线线圈具有多个横向分开的导线，其缠绕在柔性生物相容性聚合物中并且与所述加强件轴向锚固到馈通壳体上，所述线圈被非正交力吸收线圈加强件包封。 因此，被施加到天线线圈组件的这种被配置的非正交冲击力被吸收，否则将被反射成线圈平面中的拉力的其横向分量被防止在天线线圈内形成或断裂线。

公开(公告)号：US07444180B2

公开(公告)日：2008-10-28

申请号：US11138598

申请日：2005-05-25

申请人： Janusz A. Kuzma ,  Tom Xiaohai He ,  Anne Pianca

发明人： Janusz A. Kuzma ,  Tom Xiaohai He ,  Anne Pianca

IPC分类号： A61N1/00

CPC分类号： A61N1/375 ,  A61N1/0551 ,  A61N1/36003 ,  A61N1/37205 ,  A61N1/3756 ,  A61N2001/0578

摘要： An implantable microstimulator can include a housing having a first end; an electronic subassembly disposed within the housing; a plurality of electrodes disposed on the housing and coupled to the electronic subassembly; and a dissecting tip disposed at the first end of the housing. Another implantable microstimulator includes a housing having a first end; an electronic subassembly disposed within the housing; a plurality of electrodes disposed on the housing and coupled to the electronic subassembly; and a extraction aid disposed at the first end of the housing and configured and arranged for attachment of an extraction line.

摘要翻译： 可植入微型刺激器可以包括具有第一端的壳体; 设置在所述壳体内的电子组件; 多个电极，设置在所述壳体上并联接到所述电子子组件; 以及设置在所述壳体的第一端处的解剖尖端。 另一种可植入微型激励器包括具有第一端的外壳; 设置在所述壳体内的电子组件; 多个电极，设置在所述壳体上并联接到所述电子子组件; 以及设置在壳体的第一端处并被构造和布置成用于附接提取管线的提取助剂。

公开(公告)号：US20080195178A1

公开(公告)日：2008-08-14

申请号：US10987561

申请日：2004-11-12

申请人： Janusz A. Kuzma

发明人： Janusz A. Kuzma

IPC分类号： A61N1/00

CPC分类号： A61N1/375 ,  A61N1/0541 ,  A61N1/36036 ,  H04R2225/67

摘要： The present disclosure relates to fixation methods and systems used to secure an implantable medical component in the preferred location of the skull or other bony area of the body. The disclosed fixation methods and systems may be used with a component of a cochlear implant system or other implantable devices, particularly if they are equipped with silicone flaps or flanges, or the like. A mesh reinforcing material overlaps or intertwines into areas of the silicone flanges, which allows for a better distribution of the stress that may occur during the fastening process. Self-tapping screws are used to fasten the implantable component to the skull. The screws are placed in the silicone flanges where the mesh reinforcing material has been embedded. Standard suture-wire may also be used to secure the implantable component to the skull, the implantable component having mounting holes surrounded by the mesh reinforcing material.

摘要翻译： 本公开涉及用于将可植入医疗部件固定在身体的头骨或其他骨区域的优选位置中的固定方法和系统。 公开的固定方法和系统可以与耳蜗植入物系统的组件或其他可植入装置一起使用，特别是如果它们配备有硅胶片或凸缘等。 网状增强材料与硅树脂凸缘的区域重叠或交织在一起，这允许在紧固过程中可能发生的应力的更好分布。 自攻螺钉用于将可植入部件固定在头骨上。 将螺钉放置在嵌入网状增强材料的硅树脂凸缘中。 也可以使用标准缝合线将可植入组件固定到颅骨，该可植入部件具有由网状增强材料包围的安装孔。

公开(公告)号：US06968238B1

公开(公告)日：2005-11-22

申请号：US10635768

申请日：2003-08-05

申请人： Janusz A. Kuzma

发明人： Janusz A. Kuzma

IPC分类号： A61N1/05

CPC分类号： A61N1/0541 ,  A61B17/3468 ,  A61B2017/00787

摘要： An implantable electrode system, adapted for insertion into a cochlea, includes an elongate electrode array stored within a sheath. The electrode array has a multiplicity of electrode contacts carried on a flexible elongate carrier, which carrier is adapted for insertion into one of the spiraling ducts, e.g., the scala tympani, of the cochlea, and further has longitudinal channel or lumen that passes therethrough. 3-6 mm from the distal end of the electrode array. To insert the electrode system into the cochlea, a stylet wire is inserted into the channel or lumen of the electrode array while the electrode array is held within the sheath. The sheath is then removed, and the electrode array is then gently guided and pushed through a cochleostomy into the cochlea by extending the stylet wire to a desired depth. As the electrode array is thus inserted into the cochlea, the stylet wire is retracted and the electrode array remains implanted within the cochlea.

摘要翻译： 适于插入耳蜗的可植入电极系统包括存储在护套内的细长电极阵列。 电极阵列具有承载在柔性细长载体上的多个电极接触件，该载体适于插入到耳蜗的螺旋形管道（例如鼓膜鼓膜）之一中，并且还具有穿过其中的纵向通道或内腔。 距电极阵列远端3-6mm。 为了将电极系统插入耳蜗，将电极阵列保持在鞘内，将探针线插入电极阵列的通道或内腔。 然后去除护套，然后通过将探针线延伸到期望的深度，然后轻轻地将电极阵列引导并通过耳蜗切开进入耳蜗。 由于电极阵列因此被插入耳蜗，所以探针线缩回，并且电极阵列保持植入耳蜗内。

公开(公告)号：US06788975B1

公开(公告)日：2004-09-07

申请号：US10057115

申请日：2002-01-24

申请人： Todd K. Whitehurst ,  James P. McGivern ,  Janusz A. Kuzma

发明人： Todd K. Whitehurst ,  James P. McGivern ,  Janusz A. Kuzma

IPC分类号： A61N118

CPC分类号： A61N1/37205 ,  A61N1/0529 ,  A61N1/36064

摘要： A small implantable stimulator(s) with at least two electrodes is small enough to have the electrodes located adjacent to a nerve structure at least partially responsible for epileptic seizures. The small stimulator provides a means of stimulating a nerve structure(s) when desired, and may be implanted via a minimal surgical procedure.

摘要翻译： 具有至少两个电极的小型可植入刺激器足够小以使得电极位于与神经结构相邻的位置，至少部分地负责癫痫发作。 小刺激器提供了在需要时刺激神经结构的手段，并且可以通过最小的外科手术植入。

公开(公告)号：US06735475B1

公开(公告)日：2004-05-11

申请号：US10057088

申请日：2002-01-24

申请人： Todd K. Whitehurst ,  James P. McGivern ,  Carla Mann Woods ,  Paul M. Meadows ,  Janusz A. Kuzma

发明人： Todd K. Whitehurst ,  James P. McGivern ,  Carla Mann Woods ,  Paul M. Meadows ,  Janusz A. Kuzma

IPC分类号： A61N130

CPC分类号： A61N1/36071 ,  A61N1/08 ,  A61N1/37205

摘要： A small implantable stimulator(s) with at least two electrodes is small enough to have the electrodes located adjacent to a nerve structure at least partially responsible for headache and/or facial pain. The small stimulator provides a means of stimulating a nerve structure(s) when desired, and may be implanted via a minimal surgical procedure.

摘要翻译： 具有至少两个电极的小型可植入刺激器足够小以使电极位于与神经结构相邻的位置，至少部分地负责头痛和/或面部疼痛。 小刺激器提供了在需要时刺激神经结构的手段，并且可以通过最小的外科手术植入。

公开(公告)号：US06604283B1

公开(公告)日：2003-08-12

申请号：US09519015

申请日：2000-03-03

申请人： Janusz A. Kuzma

发明人： Janusz A. Kuzma

IPC分类号： H01R4300

CPC分类号： A61N1/0541 ,  Y10T29/49174 ,  Y10T29/49179 ,  Y10T29/49181 ,  Y10T29/49183 ,  Y10T29/49185 ,  Y10T29/49208 ,  Y10T29/49218

摘要： A method of manufacturing an electrode array has an elongate flexible carrier that is much more flexible in a first direction than in a second direction orthogonal thereto. The elongate flexible carrier is formed with a bias force that causes the array to flex in the first direction so as to assume the general spiral or circular shape of the scala tympani duct within the cochlea. The less-flexible direction is the direction that makes it difficult for the array to twist as it is inserted within the scala tympani duct. The bias force is sufficiently strong to cause the array to assume its preformed spiral shape even after being straightened during initial insertion into the cochlea. Electrode contacts, embedded into the carrier so as to be exposed along an inner or concave surface of the spiral, thus wrap snugly around the modiolus, thereby positioning the electrode contacts against the modiolar wall in an optimum position for stimulation.

摘要翻译： 制造电极阵列的方法具有细长的柔性载体，其在第一方向上比在与其正交的第二方向上更加柔性。 细长的柔性载体形成有使力阵列在第一方向上弯曲以产生耳蜗内鼓膜鼓风管的一般螺旋或圆形形状的偏压力。 较不灵活的方向是使阵列难以在插入鼓鼓管内扭转的方向。 偏压力足够强，即使在最初插入耳蜗时被拉直之后也使阵列呈现预先形成的螺旋形状。 电极接触，嵌入载体中以沿着螺旋的内表面或凹面暴露，从而紧密地包裹在该膜上，从而将电极接触件抵靠模块壁定位在用于刺激的最佳位置。

公开(公告)号：US06522932B1

公开(公告)日：2003-02-18

申请号：US09783237

申请日：2001-02-13

申请人： Janusz A. Kuzma ,  Carla M. Mann

发明人： Janusz A. Kuzma ,  Carla M. Mann

IPC分类号： A61N105

CPC分类号： A61N1/05 ,  A61N1/0553

摘要： A paddle-type electrode or electrode array is implantable like a percutaneously inserted lead, i.e., without requiring major surgery, and once implanted, expands to provide a platform for many electrode configurations. The electrode array is provided on a flexible, foldable, subcarrier or substrate. Such subcarrier or substrate folds or compresses during implantation, thereby facilitating its insertion using percutaneous implantation techniques and tools. Once implanted, such subcarrier or substrate expands, thereby placing the electrodes in a desired spaced-apart positional relationship, and thus achieving a desired electrode array configuration. A steering stylet may be accommodated in a lumen provided in the subcarrier or substrate. Insertion tools useful with such electrode arrays include a needle with an oblong cross-section, which accommodates the dimensions of the folded array, and also accommodates other electrode arrays that are not necessarily folded.

摘要翻译： 桨状电极或电极阵列可植入如经皮插入的引线，即不需要大量手术，并且一旦植入，扩张以提供用于许多电极构造的平台。 电极阵列设置在柔性，可折叠的副载波或衬底上。 这样的子载波或衬底在植入期间折叠或压缩，从而便于其使用经皮植入技术和工具的插入。 一旦植入，这样的副载波或衬底就会膨胀，从而将电极放置在所希望的间隔开的位置关系中，从而实现所需的电极阵列构型。 转向探针可以容纳在设置在子载波或基板中的内腔中。 与这种电极阵列有用的插入工具包括具有长方形横截面的针，其适应折叠阵列的尺寸，并且还容纳不一定折叠的其它电极阵列。

公开(公告)号：US06397110B1

公开(公告)日：2002-05-28

申请号：US09443627

申请日：1999-11-19

申请人： Janusz A. Kuzma

发明人： Janusz A. Kuzma

IPC分类号： A61N105

CPC分类号： A61N1/0541

摘要： An electrode system includes (1) an electrode array, made in a straight or curved shape, but made on a flexible carrier so that it can easily bend within a curved body cavity, such as the cochlea; and (2) a flexible positioner, molded in a curved or straight shape from a silicone polymer so as to make it easy to slide into the body cavity. Some embodiments may further include an electrode and/or a positioner guiding insert. One embodiment of the positioner includes keeper tabs at its distal end, and side walls at its proximal end, to help maintain the positioner in a desired position along the back side of the electrode array during and after the insertion process. Engagement members at a distal end of the positioner also allow detachable engagement with corresponding or mating members near the distal end of the electrode array during the insertion process, thereby allowing insertion of the positioner to cause engagement of the positioner with the electrode array, and to provide for deeper insertion of the electrode array as the positioner is inserted deeper into the cochlea. One method of insertion involves first inserting an electrode array into the scala tympani, and then second inserting the positioner into the scala tympani so as to lie between the electrode array and the outer wall of the scala tympani, thereby forcing the electrode array against the modiolar wall.

摘要翻译： 电极系统包括（1）电极阵列，其制成直线或弯曲形状，但制成在柔性载体上，使得其可容易地弯曲在弯曲的体腔内，例如耳蜗; 和（2）柔性定位器，其从硅树脂聚合物成型为弯曲或直线形状，以便容易地滑入体腔。 一些实施例还可以包括电极和/或定位器引导插入件。 定位器的一个实施例包括其远端处的保持器突出部及其近端处的侧壁，以帮助在插入过程中和之后将定位器沿着电极阵列的背侧保持在期望位置。 在定位器的远端处的接合构件还允许在插入过程期间与电极阵列的远端附近的对应或匹配构件可分离地接合，从而允许定位器插入以使定位器与电极阵列接合，并且 当定位器更深地插入耳蜗时，提供电极阵列的更深的插入。 一种插入方法包括首先将电极阵列插入鼓鼓鼓中，然后将定位器第二次插入鼓风鼓中，以便位于电极阵列和鼓风鼓的外壁之间，从而迫使电极阵列抵抗模式 壁。

公开(公告)号：US06309410B1

公开(公告)日：2001-10-30

申请号：US09375425

申请日：1999-08-17

申请人： Janusz A. Kuzma ,  Thomas H. R. Lenarz ,  Rolf-Dieter Battmer ,  Alfred E. Mann

发明人： Janusz A. Kuzma ,  Thomas H. R. Lenarz ,  Rolf-Dieter Battmer ,  Alfred E. Mann

IPC分类号： A61N105

CPC分类号： A61N1/0541

摘要： An electrode array suitable for insertion into the cochlea has a drug delivery channel therein. In a preferred embodiment, electrical stimuli may be applied near the modiolar wall of the cochlea via spaced-apart electrode contacts embedded along a front edge of a flexible carrier, which flexible carrier comprises the body of the electrode array. The front edge, and hence the electrode contacts, may be held against the modiolar wall by a flexible positioner placed on the back side of the flexible carrier. Drugs may be delivered deep into the cochlea through the drug delivery channel that passes longitudinally through the center of the flexible carrier. In an alternative embodiment, the drug delivery channel may be included within the positioner.

摘要翻译： 适于插入耳蜗的电极阵列中具有药物输送通道。 在优选实施例中，电刺激可以通过沿着柔性载体的前边缘嵌入的间隔开的电极触点施加在耳蜗的模块壁附近，该柔性载体包括电极阵列的主体。 可以通过放置在柔性载体的背侧上的柔性定位器将前边缘以及因此的电极接触件保持抵靠模块壁。 药物可以通过纵向通过柔性载体的中心的药物递送通道深入耳蜗。 在替代实施例中，药物递送通道可以包括在定位器内。