Stem cell-derived endothelial cells modified to disrupt tumor angiogenesis
    52.
    发明申请
    Stem cell-derived endothelial cells modified to disrupt tumor angiogenesis 审中-公开
    干细胞衍生的内皮细胞被修饰以破坏肿瘤血管生成

    公开(公告)号:US20060024280A1

    公开(公告)日:2006-02-02

    申请号:US11228549

    申请日:2005-09-16

    申请人: Michael West

    发明人: Michael West

    IPC分类号: C12Q1/68 A61K48/00

    摘要: The present invention provides cloned, genetically modified, endothelial cells, and the stem cells from which they are derived, which are produced by somatic cell nuclear transfer. The invention further provide novel therapeutic methods in which such cells are administered to a patient with tumors to inhibit and/or disrupt angiogenesis of the tumors, thereby inhibiting tumor growth and killing tumor cells.

    摘要翻译: 本发明提供克隆的,经遗传修饰的内皮细胞以及它们衍生的干细胞,其通过体细胞核转移产生。 本发明还提供了新的治疗方法,其中将这样的细胞施用于具有肿瘤的患者以抑制和/或破坏肿瘤的血管发生,从而抑制肿瘤生长和杀死肿瘤细胞。

    Velocity determination of the near-surface layers in the earth using exploration 2D or 3D seismic data
    53.
    发明申请
    Velocity determination of the near-surface layers in the earth using exploration 2D or 3D seismic data 审中-公开
    使用探索2D或3D地震数据测量地球近地层的速度

    公开(公告)号:US20050256648A1

    公开(公告)日:2005-11-17

    申请号:US11111907

    申请日:2005-04-22

    申请人: Michael West

    发明人: Michael West

    IPC分类号: G01V1/00 G01V1/30

    CPC分类号: G01V1/303

    摘要: Several methods for determining the near-surface layer velocity in the earth (can include the weathering layer velocity) from exploration seismic 2D or 3D data are presented. These velocity measurements are to be used in time-correcting seismic data during data processing in refraction statics, datum statics, elevation statics derivation and application or any other data processing scheme wherein the near-surface velocity is required. They can also be used as the near-surface velocity model for depth-migration of seismic data. The velocity of the near-surface is directly related to the character of the shot records themselves. By statistically measuring this character from the shot records in an automated fashion, a large amount of data can be processed and the character measurement numerically converted to a velocity measurement using benchmark velocities. A complete near-surface velocity field for the seismic survey can be created in this way and used to correct for false time-structure in seismic datasets used for hydrocarbon exploration or any other sub-surface exploration purposes.

    摘要翻译: 提出了从勘探地震2D或3D数据确定地球近地层速度的几种方法(可包括风化层速度)。 这些速度测量将用于在折射静力学,基准静力学,高程静力学推导和应用中的数据处理期间的时间校正地震数据,或者需要近地表速度的任何其他数据处理方案。 它们也可以用作地震数据深度偏移的近地表速度模型。 近地面的速度与射击记录本身的性质直接相关。 通过以自动方式从拍摄记录中统计测量此字符,可以处理大量数据,并使用基准速度将字符测量数值转换为速度测量。 可以以这种方式创建一个完整的地表速度场,用于纠正用于油气勘探或任何其他次表面勘探目的的地震数据集中的假时间结构。