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公开(公告)号：US11918830B2
公开(公告)日：2024-03-05
申请号：US17382044
申请日：2021-07-21
申请人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
发明人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
CPC分类号： A61N5/1077 , A61B6/03 , A61N5/1044 , A61N5/1067 , A61N5/1082 , G21K1/087 , G21K1/093 , G21K5/04 , A61N5/107 , A61N2005/1074 , A61N2005/1087 , A61N2005/1097 , H01J35/147
摘要： The invention comprises a method and apparatus for tuning a charged particle beam path of a charged particle beam system used to treat a tumor of a patient, comprising the steps of: positioning a two-dimensional charged particle detector in a beam line downstream from a magnet pair; operating windings of the magnet pair at a first power level to generate a first magnetic field; measuring a beam position with the first two-dimensional charged particle detector; adjusting a correction magnetic field by driving voltage of a correction coil at a second power level, the second power level less than five percent of the first power level, where the first magnetic field and the correction magnetic field combine to yield an operational magnetic field; and the steps of measuring and adjusting the correction magnetic field changing the operational magnetic field to adjust a measured beam position toward a target beam position.
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公开(公告)号：US20210387022A1
公开(公告)日：2021-12-16
申请号：US17383836
申请日：2021-07-23
申请人： Daniel J. Raymond , Artur Teymurazyan , Ran Tu , Susan L. Michaud
发明人： Daniel J. Raymond , Artur Teymurazyan , Ran Tu , Susan L. Michaud
摘要： The invention comprises a method and apparatus for aligning a charged particle beam path for treating a tumor of a patient, comprising: a cancer therapy system comprising the charged particle beam path sequentially passing: from an injector, through a synchrotron, along a beam transport line, and through a nozzle; a first two-dimensional detector configured to measure a beam state of positively charged particles; and an integrated intelligent system configured to classify the beam state into a set of beam shape factors, the integrated intelligent system configured to correct the beam shape through application of a condition-action rule: (1) adjusting a first voltage delivered to a first magnet positioned in the beam line prior to the first two-dimensional detector and (2) altering the beam shape through application of a second voltage to a second magnet position in the beam line adjacent to the first magnet.
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公开(公告)号：US11918831B2
公开(公告)日：2024-03-05
申请号：US17464665
申请日：2021-09-01
申请人： Susan L. Michaud , Ran Tu , Daniel J. Raymond
发明人： Susan L. Michaud , Ran Tu , Daniel J. Raymond
CPC分类号： A61N5/1077 , A61B6/03 , A61N5/1044 , A61N5/1067 , A61N5/1082 , G21K1/087 , G21K1/093 , G21K5/04 , A61N5/107 , A61N2005/1074 , A61N2005/1087 , A61N2005/1097 , H01J35/147
摘要： The invention comprises a method and apparatus for treating a tumor of a patient with positively charged particles, comprising the steps of transporting the positively charged particles along a beam transport path passing sequentially from an accelerator, through a beam transport line, through a nozzle, and toward a position of the patient, the step of transporting further comprising the steps of: (1) terminating a first Bragg peak, of a first set of the positively charged particles, in a position of the tumor and (2) flash treating the tumor with a second Bragg peak, of a second set of the positively charged particles, the second Bragg peak terminating post-patient relative to the nozzle. Optionally the second set of particles are delivered at a rate exceeding one MHz. Optionally, particles in common are used to both treat the tumor and image the tumor.
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公开(公告)号：US20240066325A1
公开(公告)日：2024-02-29
申请号：US18387604
申请日：2023-11-07
申请人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
发明人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
CPC分类号： A61N5/1077 , A61B6/03 , A61N5/1044 , A61N5/1067 , A61N5/1082 , G21K1/087 , G21K1/093 , G21K5/04 , A61N5/107 , A61N2005/1074 , A61N2005/1087 , A61N2005/1097 , H01J35/147
摘要： The invention comprises a method and apparatus for tuning a charged particle beam path of a charged particle beam system used to treat a tumor of a patient, comprising the steps of: positioning a two-dimensional charged particle detector in a beam line downstream from a magnet pair; operating windings of the magnet pair at a first power level to generate a first magnetic field; measuring a beam position with the first two-dimensional charged particle detector; adjusting a correction magnetic field by driving voltage of a correction coil at a second power level, the second power level less than five percent of the first power level, where the first magnetic field and the correction magnetic field combine to yield an operational magnetic field; and the steps of measuring and adjusting the correction magnetic field changing the operational magnetic field to adjust a measured beam position toward a target beam position.
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公开(公告)号：US20210393987A1
公开(公告)日：2021-12-23
申请号：US17464665
申请日：2021-09-01
申请人： Susan L. Michaud , Ran Tu , Daniel J. Raymond
发明人： Susan L. Michaud , Ran Tu , Daniel J. Raymond
摘要： The invention comprises a method and apparatus for treating a tumor of a patient with positively charged particles, comprising the steps of transporting the positively charged particles along a beam transport path passing sequentially from an accelerator, through a beam transport line, through a nozzle, and toward a position of the patient, the step of transporting further comprising the steps of: (1) terminating a first Bragg peak, of a first set of the positively charged particles, in a position of the tumor and (2) flash treating the tumor with a second Bragg peak, of a second set of the positively charged particles, the second Bragg peak terminating post-patient relative to the nozzle. Optionally the second set of particles are delivered at a rate exceeding one MHz. Optionally, particles in common are used to both treat the tumor and image the tumor.
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公开(公告)号：US20210353966A1
公开(公告)日：2021-11-18
申请号：US17382044
申请日：2021-07-21
申请人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
发明人： Susan L. Michaud , Daniel J. Raymond , Artur Teymurazyan , Ran Tu
摘要： The invention comprises a method and apparatus for tuning a charged particle beam path of a charged particle beam system used to treat a tumor of a patient, comprising the steps of: positioning a two-dimensional charged particle detector in a beam line downstream from a magnet pair; operating windings of the magnet pair at a first power level to generate a first magnetic field; measuring a beam position with the first two-dimensional charged particle detector; adjusting a correction magnetic field by driving voltage of a correction coil at a second power level, the second power level less than five percent of the first power level, where the first magnetic field and the correction magnetic field combine to yield an operational magnetic field; and the steps of measuring and adjusting the correction magnetic field changing the operational magnetic field to adjust a measured beam position toward a target beam position.
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公开(公告)号：US09907981B2
公开(公告)日：2018-03-06
申请号：US15382401
申请日：2016-12-16
CPC分类号： A61N5/1077 , A61N2005/1087 , A61N2005/1095 , G21K1/02 , G21K1/10 , G21K5/04 , H01J27/16
摘要： The invention comprises a system for patient specific control of charged particles in a charged particle beam path using one or more trays inserted into the charged particle beam path, such as at the exit port of a gantry nozzle in close proximity to a tumor of a patient. Each tray holds an insert, such as a patient specific insert for controlling the energy, focus depth, and/or shape of the charged particle beam. Examples of inserts include a range shifter, a compensator, an aperture, a ridge filter, and a blank. Trays in a tray assembly are optionally retracted into an output nozzle of a charged particle cancer treatment system. Optionally and preferably, each tray communicates a held and positioned insert to a main controller of the charged particle cancer therapy system.
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公开(公告)号：US20170252580A1
公开(公告)日：2017-09-07
申请号：US15382401
申请日：2016-12-16
CPC分类号： A61N5/1077 , A61N2005/1087 , A61N2005/1095 , G21K1/02 , G21K1/10 , G21K5/04 , H01J27/16
摘要： The invention comprises a system for patient specific control of charged particles in a charged particle beam path using one or more trays inserted into the charged particle beam path, such as at the exit port of a gantry nozzle in close proximity to a tumor of a patient. Each tray holds an insert, such as a patient specific insert for controlling the energy, focus depth, and/or shape of the charged particle beam. Examples of inserts include a range shifter, a compensator, an aperture, a ridge filter, and a blank. Trays in a tray assembly are optionally retracted into an output nozzle of a charged particle cancer treatment system. Optionally and preferably, each tray communicates a held and positioned insert to a main controller of the charged particle cancer therapy system.
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