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    CONTROL OF A RADIOTHERAPY DEVICE
    2.
    发明公开
    CONTROL OF A RADIOTHERAPY DEVICE 审中-公开

    公开(公告)号：US20240252838A1

    公开(公告)日：2024-08-01

    申请号：US18040476

    申请日：2021-08-19

    申请人： Elekta Limited

    发明人： Chris Knox

    IPC分类号： A61N5/10

    CPC分类号： A61N5/103 ,  A61N5/1045 ,  A61N5/1067 ,  A61N5/107 ,  A61N5/1081 ,  A61N2005/1074

    摘要： A radiotherapy device, a computer-implemented method and a computer-readable medium are disclosed. The radiotherapy device includes a radiation source, one or more imaging systems and a controller communicatively coupled to the radiation source and the one or more imaging systems. The radiation source is configured to apply radiation to a treatment region coinciding with a subject according to a treatment plan. The one or more imaging systems are configured to generate image data for the subject. The controller is configured to: determine, based on the image data, a relative distance between a target region of the subject and an organ at risk of the subject, wherein the treatment plan comprises a prescribed dose for the target region; determine a buffer region around the target based at least in part on the relative distance; and generate a control signal for adjusting a radiotherapy treatment in response to determining, based on the image data, that the treatment region is located at least partially outside the buffer region.

    GRADIENT OPTIMIZED RADIAL TREATMENT (GORT)
    3.
    发明公开
    GRADIENT OPTIMIZED RADIAL TREATMENT (GORT) 审中-公开

    公开(公告)号：US20240245931A1

    公开(公告)日：2024-07-25

    申请号：US18099668

    申请日：2023-01-20

    申请人： Michael D. Weil

    发明人： Michael D. Weil

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1039 ,  A61N5/1067 ,  A61N5/1084 ,  A61N2005/005

    摘要： The present invention relates to the field of medical therapy of lesions detrimental to a body. The system is capable of treatment with a non-invasive, ionizing kV energy radiation source. Locally focused energy can be used to definitively treat, or as an adjuvant to enhance immune modulators, to eliminate tumors. Distributed external beam entry points produce a significant advantageous dose profile at depth as intersecting beams accumulate in a narrow focus to treat a selected volume. Targeted disease may have enhanced sensitivity to the radiation by taking up an ionizing-radiation, treatment-localizing agent. This increases the effectiveness of an energy dose in the lesion. The pattern of beam output is effectively directed towards a desired location and kV x-rays traveling towards undesired locations, such as healthy tissue, are quenched. Targeting a lesion within the body with volumetrically discrete energy dose deposition can beneficially impact harmful lesions. Aiming the beam at a pathologic target is done while moving an x-ray source mechanically around a patient to distribute surface dose. The purpose of the focused energy deposition is to destroy and disable pathologic physiology, such as malignant masses. More specifically this invention relates to a system, which optimizes delivery of ionizing kV beams to a lesion alone or one containing treatment-localizing agents in higher concentration than the surrounding normal tissues. Thereby an optimal delivery of ionizing radiation becomes more destructive to a mass of abnormal cells upon interaction with the targeted site.

    Systems and methods for magnetic field localization of charged particle beam end point
    6.
    发明授权
    Systems and methods for magnetic field localization of charged particle beam end point 有权

    公开(公告)号：US11904183B2

    公开(公告)日：2024-02-20

    申请号：US17578078

    申请日：2022-01-18

    申请人： Elekta Pty Ltd.

    发明人： Stuart Julian Swerdloff

    IPC分类号： A61N5/10 ,  G01R33/10

    CPC分类号： A61N5/1067 ,  A61N5/1038 ,  G01R33/10 ,  A61N2005/1087

    摘要： Embodiments of the present disclosure are directed to radiotherapy systems. An exemplary radiotherapy system may comprise a radiotherapy output configured to deliver a charged particle beam to a patient. The system may also comprise a detector array. The detector array may have an axis that extends parallel to an axis along which the charged particle beam is delivered by the radiotherapy output. The detector array may comprise a plurality of detectors configured to detect a magnetic field generated by the charged particle beam during delivery of the charged particle beam from the radiotherapy output.

    Adversarial prediction of radiotherapy treatment plans
    7.
    发明授权
    Adversarial prediction of radiotherapy treatment plans 有权

    公开(公告)号：US11896847B2

    公开(公告)日：2024-02-13

    申请号：US17304500

    申请日：2021-06-22

    申请人： Elekta, Inc.

    发明人： Lyndon Stanley Hibbard

    IPC分类号： A61N5/10 ,  G06N3/08 ,  G16H20/40 ,  G06T7/00 ,  G06N3/045

    CPC分类号： A61N5/1047 ,  A61N5/1031 ,  A61N5/1067 ,  G06N3/045 ,  G06N3/08 ,  G06T7/0012 ,  G16H20/40 ,  G06T2200/08 ,  G06T2207/20081 ,  G06T2207/20084

    摘要： Systems and methods are disclosed for generating radiotherapy treatment machine parameters based on projection images of a target anatomy. The systems and methods include operations including receiving a set of pairs of image data for each gantry angle of a radiotherapy treatment machine, wherein each pair of the set of pairs comprises a given projection image that represents a view of an anatomy of a subject from a given gantry angle and a given graphical aperture image of multi-leaf collimator (MLC) leaf positions at the given gantry angle based on the given projection image; training a generative adversarial network (GAN) model based on the set of pairs of image data for each gantry angle; and using the trained GAN model to predict an aperture image of MLC leaf positions for a desired gantry angle based on a projection image that represents a view of an anatomical region of interest.

    DEVICE AND METHOD FOR TUNING A CHARGED PARTICLE BEAM POSITION
    8.
    发明公开
    DEVICE AND METHOD FOR TUNING A CHARGED PARTICLE BEAM POSITION 审中-公开

    公开(公告)号：US20240024702A1

    公开(公告)日：2024-01-25

    申请号：US18224643

    申请日：2023-07-21

    申请人： ION BEAM APPLICATIONS

    发明人： David Chris HERTLEIN ,  François VANDER STAPPEN ,  Rudi LABARBE

    IPC分类号： A61N5/10 ,  H05H7/04

    CPC分类号： A61N5/1067 ,  H05H7/04 ,  A61N5/1078 ,  A61N5/1043 ,  H05H2007/046 ,  H05H2277/11 ,  H05H13/00

    摘要： A particle therapy apparatus configured to scan a charged particle beam over a target according to a pre-defined treatment field which covers a treatment surface in an isocenter plane of the apparatus. The apparatus is capable of scanning the beam over a reachable surface which covers and is larger than the treatment surface. A beam stopper is arranged downstream of the scanning magnets of the apparatus, at a position to prevent the beam from reaching at least a portion of the reachable surface and to allow the beam to reach any portion of the treatment surface. A control system is configured to control the apparatus to direct the beam to the beam stopper and to meanwhile measure a position of the beam, to calculate a difference between a desired position and the measured position of the beam when directed to the beam stopper, and to scan the beam over the target according to the pre-defined treatment field by taking into account the calculated difference.