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公开(公告)号：US07937149B2
公开(公告)日：2011-05-03
申请号：US10727074
申请日：2003-12-03
IPC分类号： A61N1/365
CPC分类号： A61B5/02055 , A61B5/0031 , A61B5/0215 , A61B5/024 , A61B5/145 , A61N1/37258 , A61N1/37282 , G06F19/00 , G06K9/00496
摘要： A method and apparatus for detection of changes in physiologic parameters of a patient that includes generating measured physiologic parameters, generating an adaptive baseline trend of the measured physiologic parameters corresponding to a first time period, generating a short term trend of the measured physiologic parameters corresponding to a second time period less than the first time period, and generating a metric of physiologic parameter change between the adaptive baseline trend and one of a most recent measured physiologic parameter and the short term trend of the measured physiologic parameters.
摘要翻译： 一种用于检测患者的生理参数变化的方法和装置，包括产生测量的生理参数，产生对应于第一时间段的所测量的生理参数的适应基线趋势，产生对应于的测量生理参数的短期趋势 第二时间段小于第一时间段，并且在自适应基线趋势与最近测量的生理参数之一以及所测量的生理参数的短期趋势之间产生生理参数变化的度量。
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公开(公告)号：US07937135B2
公开(公告)日：2011-05-03
申请号：US11742628
申请日：2007-05-01
IPC分类号： A61B5/0402
CPC分类号： A61N1/3925 , A61N1/3704
摘要： A method and apparatus for determining oversensing in a medical device that includes sensing cardiac signals, determining an oversensing characteristic associated with cardiac signals sensed during a predetermined sensing window, identifying oversensing in response to the oversensing characteristic, determining, in response to oversensing being identified, an adjusting characteristic associated with cardiac signals sensed during the predetermined sensing window, and updating a sensing parameter in response to the determined adjusting characteristic.
摘要翻译： 一种用于确定医疗装置中的过度感测的方法和装置，包括感测心脏信号，确定与在预定感测窗口期间感测到的心脏信号相关联的过度感应特征，响应于过敏特性识别过敏，响应于被识别的过冷而确定， 与在预定感测窗口期间感测到的心脏信号相关联的调整特性，以及响应于确定的调整特性来更新感测参数。
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公开(公告)号：US20100137935A1
公开(公告)日：2010-06-03
申请号：US12700454
申请日：2010-02-04
CPC分类号： A61N1/3627 , A61N1/3684 , A61N1/371
摘要： The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate to ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or “CRT”).
摘要翻译： 本发明提供了用于在非跟踪起搏模式（例如，DDI / R，VVI / R）中确定心室起搏刺激是否捕获节奏心室的方法和装置，包括以下方面中的一些或全部。 例如，将心室起搏速率提高到高于最近心率的超速起搏速率的标称值，并评估从第一起搏心室到第二感测心室的传导间隔，然后继续监测潜在速率，以确保 阈值测试起搏速率不会超过预定的最小间隔，并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是子阈值和超阈值之一。 所述方法和装置与确保心室起搏方案（例如，心脏再同步治疗或“CRT”）的实际递送相结合特别有用。
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公开(公告)号：US20090299422A1
公开(公告)日：2009-12-03
申请号：US12182687
申请日：2008-07-30
IPC分类号： A61N1/08 , A61B5/0432
CPC分类号： A61N1/3702 , A61B5/042 , A61B5/046 , A61B5/0464 , A61B5/053 , A61B5/0538 , A61B5/7264 , A61B2560/0276 , A61N1/3704 , A61N2001/083
摘要： Techniques for storing electrograms (EGMS) that are associated with sensed episodes or events that may be non-physiological and, instead, associated with a sensing integrity condition are described. In some examples, a device or system identifies suspected non-physiological NSTs, and stores an EGM for the suspected non-physiological NSTs within an episode log. In some examples, a device or system determines whether to store an EGM for a suspected non-physiological episode or event based on whether an impedance integrity criterion has been satisfied. For example, a device or system may store an EGM for a detected short interval if the impedance integrity criterion has been met. In some examples, a device or system determines whether to buffer EGM data based on whether an impedance integrity criterion or other sensing integrity criterion has been met.
摘要翻译： 描述了用于存储与可能是非生理感知的事件相关联的电摄影（EGMS）的技术，并且相反地与感测完整性条件相关联的技术。 在一些示例中，设备或系统识别疑似非生理NST，并且在发作日志中存储用于可疑非生理NST的EGM。 在一些示例中，设备或系统基于是否已经满足阻抗完整性标准来确定是否存储用于可疑非生理事件或事件的EGM。 例如，如果已经满足了阻抗完整性标准，则设备或系统可以存储用于检测到的短间隔的EGM。 在一些示例中，设备或系统基于是否已经满足阻抗完整性标准或其他感测完整性标准来确定是否缓冲EGM数据。
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公开(公告)号：US07555336B2
公开(公告)日：2009-06-30
申请号：US11312163
申请日：2005-12-20
IPC分类号： A61B5/0402
CPC分类号： A61N1/371 , A61N1/3712
摘要： The present invention provides a technique for verifying pacing capture of a ventricular chamber, particularly to ensure desired delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or “CRT”). The invention also provides for ventricular capture management by delivering a single ventricular pacing stimulus and checking inter-ventricular conduction during a temporal window to determine if the ventricular pacing stimulus captured the chamber. If a loss-of-capture (LOC) signal results from the capture management testing, then the characteristics of the applied pacing pulses are modified and the conduction test repeated. In the event that the LOC signal persists, a pacing mode-switch to an atrial-based pacing therapy and/or non-bi-ventricular pacing regimen can be implemented.
摘要翻译： 本发明提供了一种用于验证心室的起搏捕获的技术，特别是确保心室起搏方案（例如，心脏再同步治疗或“CRT”）的期望递送。 本发明还通过递送单个心室起搏刺激和在时间窗口期间检查心室间传导来确定心室起搏刺激是否捕获腔室来提供心室捕获管理。 如果捕获管理测试产生捕获损失（LOC）信号，则应用起搏脉冲的特性被修改，并重复传导测试。 在LOC信号持续存在的情况下，可以实现起搏模式切换到基于心房的起搏治疗和/或非双心室起搏方案。
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56.发明申请公开(公告)号：US20080275519A1
公开(公告)日：2008-11-06
申请号：US11742618
申请日：2007-05-01
IPC分类号： A61N1/00
CPC分类号： A61N1/3925 , A61N1/3704
摘要： A method and apparatus for adjusting a sensing parameter in a medical device that includes a sensing electrode sensing cardiac signals, a processor to determine an adjusting characteristic associated with the cardiac signals sensed over a predetermined sensing window, and a control unit to update the sensing parameter in response to the determined adjusting characteristic.
摘要翻译： 一种用于调整包括感测心脏信号的感测电极的医疗装置中的感测参数的方法和装置，用于确定与在预定感测窗口上感测到的心脏信号相关联的调整特性的处理器以及用于更新感测参数的控制单元 响应于确定的调整特性。
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公开(公告)号：US20080275516A1
公开(公告)日：2008-11-06
申请号：US11742625
申请日：2007-05-01
IPC分类号： A61N1/00
CPC分类号： A61N1/3704 , A61B5/0456 , A61B5/046 , A61B5/7239 , A61N1/3925
摘要： A method and apparatus of updating a sensing parameter in a medical device that includes sensing cardiac signals, determining intervals in response to the sensed cardiac signals, determining interval patterns associated with the determined intervals, and updating the sensing parameter in response to the determined interval patterns.
摘要翻译： 一种更新医疗设备中的感测参数的方法和装置，包括感测心脏信号，响应于感测的心脏信号确定间隔，确定与所确定的间隔相关联的间隔模式，以及响应于所确定的间隔模式来更新感测参数 。
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58.发明授权AV synchronous cardiac pacing system delivering multi-site ventricular pacing triggered by a ventricular sense event during the AV delay 失效AV同步心脏起搏系统在AV延迟期间提供由心室感觉事件触发的多部位心室起搏公开(公告)号：US06477415B1
公开(公告)日：2002-11-05
申请号：US09439243
申请日：1999-11-12
IPC分类号： A61N1362
CPC分类号： A61N1/3622 , A61N1/3627
摘要： A pacing system for selectively sensing spontaneous ventricular cardiac depolarizations at first and second spaced apart ventricular sites during the time-out of an AV delay and delivering pace pulses to the spaced apart ventricular sites in a triggered pacing mode. The first and second ventricular sites are preferably right ventricular (RV) and left ventricular (LV) pace/sense electrode sites, and RV event and LV event signals are sensed at the RV and LV pace/sense electrodes. A V-A pacing escape interval and a ventricular refractory period, a trigger pace window, an upper rate interval and further post-event time periods are started upon a RV or LV sense event or a first ventricular pace pulse delivered upon time-out of the AV delay. A triggered ventricular pace pulse or pulses is delivered to one or both of the RV and LV pace/sense electrode sites upon detecting an RV sense event or LV sense event during the AV delay. In one triggered pacing mode, a RV or LV pace pulse is delivered upon a RV or LV sense event during the AV delay to one of the RV or LV pace/sense electrode sites. In another triggered pacing mode, a triggered pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after a triggered pacing delay timed from a non-refractory RV or LV sense event occurring during the AV delay. In still another triggered pacing mode, a first pace pulse is delivered upon a RV or LV sense event, the triggered pacing delay is timed out, and a second pace pulse is delivered to the other one of the RV or LV pace/sense electrode sites after time-out of the triggered pacing delay. Triggered ventricular pacing is disabled during the V-A escape interval. Such a system could be employed in pacemakers that are part of a cardio defibrillator system if desired.
摘要翻译： 一种起搏系统，用于在AV延迟超时期间选择性地感测在第一和第二间隔开的心室位置处的自发心室心脏去极化并且以触发的起搏模式将起搏脉冲递送到间隔开的心室部位。 第一和第二心室位置优选为右心室（RV）和左心室（LV）步速/感测电极位置，并且在RV和LV起搏/感测电极处感测RV事件和LV事件信号。 在RV或LV感测事件或AV超时后传送的第一心室起搏脉冲时开始VA起搏逃避间隔和心室不应期，触发速度窗口，高速率间隔和事件后时间段 延迟。 在AV延迟期间检测到RV感测事件或LV感测事件或LV感测事件时，触发的心室起搏脉冲或脉冲被传送到RV和LV起搏/感测电极位置中的一个或两个。 在一个触发的起搏模式中，RV或LV起搏脉冲在AV延迟期间的RV或LV感测事件处被递送到RV或LV步速/感测电极位置之一。 在另一个触发的起搏模式中，在从AV延迟期间发生的非难易的RV或LV感测事件定时触发的起搏延迟之后，将触发的起搏脉冲传送到RV或LV起搏/感测电极位置中的另一个。 在又一个触发起搏模式中，在RV或LV感测事件上传送第一步速脉冲，触发的起搏延迟被超时，并且第二步速脉冲被传送到RV或LV步速/感测电极位置中的另一个 超时触发的起搏延时。 触发式心室起搏在V-A逃逸间隔期间被禁用。 如果需要，这种系统可以用于作为心脏除颤器系统的一部分的起搏器。
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公开(公告)号：US06466820B1
公开(公告)日：2002-10-15
申请号：US09439078
申请日：1999-11-12
IPC分类号： A61N118
CPC分类号： A61N1/3622 , A61N1/3627
摘要： Multi-site cardiac pacing systems for providing pacing to multiple spaced apart sites of a patient's heart, including especially but not limited to sites in right heart chamber (RHC) and left heart chamber (LHC), in triggered pacing modes while avoiding inappropriate delivery of triggered pacing to the RHC and/or LHC on a non-refractory sense event that occurs early in the cardiac cycle.
摘要翻译： 多点心脏起搏系统，用于在触发的起搏模式中为患者心脏的多个间隔开的位置提供起搏，包括特别但不限于右心室（RHC）和左心室（LHC）中的部位，同时避免不适当地传递 在心脏周期早期发生的非难易感觉事件触发对RHC和/或LHC起搏。
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公开(公告)号：US08744560B2
公开(公告)日：2014-06-03
申请号：US13250676
申请日：2011-09-30
IPC分类号： A61B5/0456
CPC分类号： A61N1/37247 , A61B5/0031 , A61B5/044 , A61B5/0452 , A61B5/0464 , A61B5/0468 , A61B5/076 , A61B5/7217 , A61B5/7264
摘要： The present disclosure is directed to generating and displaying an electrogram (EGM) summary for use by physicians or other clinicians. An implantable medical device (IMD) transmits EGM signal data for a number of cardiac episodes to an external computing device. The external computing device selects a subset of the cardiac episodes for which information or images are displayed to the user. In various examples, cardiac episodes may be selected for display based at least in part on a retrospective analysis classification of the cardiac episode.
摘要翻译： 本公开涉及生成和显示用于医生或其他临床医师使用的电描记图（EGM）摘要。 可植入医疗装置（IMD）向多个心脏发作的EGM信号数据发送到外部计算装置。 外部计算设备选择向用户显示信息或图像的心脏发作的子集。 在各种示例中，可以至少部分地基于心脏发作的回顾性分析分类来选择心脏发作来进行显示。
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