公开(公告)号：US20140147470A1

公开(公告)日：2014-05-29

申请号：US14233365

申请日：2012-07-18

申请人： Masato Mitsuhashi ,  Yoichi Kato

发明人： Masato Mitsuhashi ,  Yoichi Kato

IPC分类号： C12Q1/68

摘要： Embodiments of the invention relate generally to ex vivo methods of quantifying expression of leukocyte-function associated mRNAs and using the quantification to characterize an individual's potential responsiveness to cancer immunotherapy. Certain embodiments relate to methods to monitor the efficacy of ongoing cancer immunotherapy by evaluating expression of leukocyte-function associated mRNAs genes before and administration of an anti-cancer immunotherapy regimen.

摘要翻译： 本发明的实施方案一般涉及量化白细胞功能相关mRNA表达的离体方法，并且使用定量来表征个体对癌症免疫治疗的潜在反应性。 某些实施方案涉及通过评估白细胞功能相关mRNA基因的表达并施用抗癌免疫治疗方案来监测正在进行的癌症免疫治疗的功效的方法。

公开(公告)号：US08597102B2

公开(公告)日：2013-12-03

申请号：US13068865

申请日：2011-06-20

申请人： Kenta Kitamura ,  Yoichi Kato ,  Makoto Miyawaki ,  Hiromoto Yamauchi

发明人： Kenta Kitamura ,  Yoichi Kato ,  Makoto Miyawaki ,  Hiromoto Yamauchi

IPC分类号： A63F9/24 ,  A63F13/00

CPC分类号： G07F17/3223 ,  G07F17/3272

摘要： A gaming machine 10 includes: a display device configured to display a plurality of symbols to be continuously arranged; and a controller 30. The controller 30 executes processing operations of: (a1) sequentially executing game processing for a plurality of players and then according to a result of the game processing, determining any of the symbols is to be assigned to a respective one of the players; (a2) paying out a prize according to the symbols that are assigned according to a result of the determination; and (a3) generating a scramble event in which the assigned symbols are scrambled between the plurality of players, in a case where the prize is identical as to the plurality of players.

摘要翻译： 游戏机10包括：显示装置，被配置为显示要连续排列的多个符号; 和控制器30.控制器30执行以下处理操作：（a1）对多个玩家顺序执行游戏处理，然后根据游戏处理的结果，将任何符号分配给相应的一个 玩家们; （a2）根据确定结果分配的符号支付奖品; 以及（a3）在奖品与多个玩家相同的情况下，生成其中所分配的符号在多个玩家之间加扰的加扰事件。

公开(公告)号：US08556699B2

公开(公告)日：2013-10-15

申请号：US13194794

申请日：2011-07-29

申请人： Yoichi Kato ,  Kensaku Yoshikawa

发明人： Yoichi Kato ,  Kensaku Yoshikawa

IPC分类号： A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00

CPC分类号： G07F17/32 ,  G07F17/3267

摘要： A gaming machine, includes: a symbol display device capable of scrolling a plurality of symbols on the reels; an input device which enables a player operation to input an instruction; a controller programmed to execute the processes of rearranging symbols by scrolling them in the symbol display device, and stopping the scroll thereafter, running a unit game which awards a payout to the player when symbols rearranged form a winning combination, and when a predetermined condition is met, enabling in a subsequent unit game the scroll of symbols to be stopped in response to a stop operation input through the input device.

摘要翻译： 一种游戏机，包括：能够滚动所述卷轴上的多个符号的符号显示装置; 使播放器操作能够输入指令的输入装置; 控制器被编程为执行通过在符号显示装置中滚动符号来重新排列符号的处理，并且此后停止滚动，运行单元游戏，当从匹配组合重新排列符号时，执行奖励给玩家的支付，并且当预定条件是 在随后的单元游戏中启用响应于通过输入设备输入的停止操作而停止的符号的滚动。

公开(公告)号：US08393953B2

公开(公告)日：2013-03-12

申请号：US12249482

申请日：2008-10-10

申请人： Hiroyuki Nishimura ,  Yoichi Kato ,  Hiroki Saito

发明人： Hiroyuki Nishimura ,  Yoichi Kato ,  Hiroki Saito

IPC分类号： A63F9/24 ,  A63F13/00

CPC分类号： G07F17/34 ,  G07F17/3202 ,  G07F17/3216 ,  G07F17/3244 ,  G07F17/3262 ,  G07F17/3267

摘要： Before the start of a free game, a slot machine displays a selection screen on a variable display portion and accepts a selection made by the player with respect to the first choice image and the second choice image. The first special reel band or the second special reel band including a larger number of condor symbols than the normal reel band is associated by lottery to the first choice image and the second choice image. The main CPU changes the normal reel band associated to each reel display portion to a special reel band based on the selection made by the player. Then, the main CPU executes a free game using the special reel band that was changed.

摘要翻译： 在开始免费游戏之前，老虎机在可变显示部分上显示选择画面，并接受玩家相对于第一选择图像和第二选择图像的选择。 第一特殊卷带或第二特殊卷带，其包括比正常卷轴带更多数量的隐蔽器符号，通过彩票与第一选择图像和第二选择图像相关联。 主CPU基于玩家的选择，将与每个卷轴显示部分相关联的正常卷轴带改变为特殊卷轴带。 然后，主CPU使用更改的特殊卷轴带执行免费游戏。

公开(公告)号：US08388431B2

公开(公告)日：2013-03-05

申请号：US12894802

申请日：2010-09-30

申请人： Yoichi Kato

发明人： Yoichi Kato

IPC分类号： A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00

CPC分类号： G07F17/32 ,  G07F17/3244 ,  G07F17/3258 ,  G07F17/3267 ,  G07F17/3276

摘要： A gaming machine of the present invention includes slot machines each of which repeatably runs, independently of the other slot machines, a unit game which scroll displays a base game symbol column image and stops the scroll-display to rearrange base game symbols. In response to a common game start command from a center controller, each slot machine runs, in sync with other slot machines, a common game which executes a common scrolling process in which a common game symbol column image which is different from the base game symbol column image is scroll displayed, and then stopped to rearrange common game symbols.

摘要翻译： 本发明的游戏机包括与其他老虎机独立地重复运行的老虎机，滚动显示基本游戏符号列图像并停止滚动显示以重新排列基本游戏符号的单位游戏。 响应于来自中央控制器的常规游戏开始命令，每个老虎机与其他老虎机同步地运行常规游戏，该游戏执行公共滚动处理，其中与基本游戏符号不同的公共游戏符号列图像 列图像滚动显示，然后停止重新排列常见的游戏符号。

公开(公告)号：US20120309501A1

公开(公告)日：2012-12-06

申请号：US13068862

申请日：2011-06-02

申请人： Kenta KITAMURA ,  Yoichi Kato ,  Makoto Miyawaki ,  Hiromoto Yamauchi

发明人： Kenta KITAMURA ,  Yoichi Kato ,  Makoto Miyawaki ,  Hiromoto Yamauchi

IPC分类号： A63F9/24

CPC分类号： G07F17/3202

摘要： A gaming machine includes: a common display device that displays a route made of a plurality of continuous frames; a plurality of game terminals; a bet input portion that is provided in each of the game terminals, for placing a bet in each unit game; a number-of-movements determining portion that determines by means of random numbers a number of frames, in a case where a bet is placed; a number-of-movements display portion that displays the number of the frames; a character movement portion that moves the character in accordance with the number of the frames in the route; an event executing portion that executes an event associated with the frame at which the character stops; and a prize awarding portion that awards a prize in accordance with a result of the event.

摘要翻译： 游戏机包括：显示由多个连续帧构成的路线的公共显示装置; 多个游戏终端; 设置在每个游戏终端中的用于在每个单元游戏中进行投注的投注输入部分; 在放置赌注的情况下，通过随机数确定多个帧的多个运动确定部分; 显示帧数的多个运动显示部分; 字符移动部，其根据所述路径中的帧的数量来移动所述字符; 事件执行部，其执行与所述字符停止的帧相关联的事件; 以及根据事件结果奖励奖品的奖励部分。

公开(公告)号：US08323090B2

公开(公告)日：2012-12-04

申请号：US12209534

申请日：2008-09-12

申请人： Yoichi Kato ,  Arata Ajiro ,  Kenta Sugano

发明人： Yoichi Kato ,  Arata Ajiro ,  Kenta Sugano

IPC分类号： A63F9/24

CPC分类号： G07F17/3258 ,  G07F17/32

摘要： A gaming system of the present invention comprises a plurality of gaming machines and a control device including a processor, and the processor is programmed to execute processing of (A) cumulatively counting a part of the number of betted game media as a cumulative value based on the number-of-game-media information received from the gaming machine, and (B) paying out the game media in number based on the cumulative value to any of the gaming machines, as well as displaying a numeral image corresponding to the cumulative value to the common display, when the cumulative value has reached a predetermined value.

摘要翻译： 本发明的游戏系统包括多个游戏机和包括处理器的控制装置，并且处理器被编程为执行（A）累积计数下注的游戏媒体数量的一部分作为累积值的处理 从游戏机接收到的游戏数量的媒体信息，以及（B）基于累积值将游戏媒体数量支付给游戏机，以及显示对应于累积值的数字图像 当累积值达到预定值时，到公共显示。

公开(公告)号：US08298070B2

公开(公告)日：2012-10-30

申请号：US12474935

申请日：2009-05-29

申请人： Yoichi Kato ,  Kensaku Yoshikawa

发明人： Yoichi Kato ,  Kensaku Yoshikawa

IPC分类号： A63F9/24 ,  A63F13/00 ,  G06F17/00

CPC分类号： G07F17/32 ,  G07F17/3267

摘要： A gaming machine is arranged as follows: on condition that a game medium is betted, plural symbols including a specific symbol are rearranged based on a symbol randomly selected from the plural symbols; a base game in which a game medium with an amount determined in accordance with the rearranged symbols is run; if in the base game the specific symbol is rearranged with a first predetermined condition, a special game in which a free game is repeated plural times, in the free game a special status in which the specific symbol is added to the plural symbols being established and a game medium with an amount determined in accordance with the rearranged symbols; and another free game is added and made runnable if in the special game the specific symbol is rearranged with a second predetermined condition.

摘要翻译： 游戏机的配置如下：在游戏媒体被下注的情况下，包含特定符号的多个符号基于从多个符号中随机选择的符号重新排列; 基本游戏，其中运行根据重新排列的符号确定的量的游戏媒体; 如果在基本游戏中，以第一预定条件重新排列特定符号，则在游戏中，在自由游戏中将特定符号添加到正在建立的多个符号的特殊状态， 具有根据重新排列的符号确定的量的游戏介质; 并且如果在特殊游戏中具有第二预定条件重新排列特定符号，则添加另一个免费游戏并运行。

公开(公告)号：US08267776B2

公开(公告)日：2012-09-18

申请号：US12193592

申请日：2008-08-18

申请人： Arata Ajiro ,  Yoichi Kato ,  Kenta Sugano

发明人： Arata Ajiro ,  Yoichi Kato ,  Kenta Sugano

IPC分类号： A63F9/24 ,  A63F13/00 ,  A63F1/18 ,  G06F17/00 ,  G06F19/00 ,  A63B71/00

CPC分类号： G07F17/3258 ,  G07F17/32

摘要： A gaming machine includes: a base game; gaming terminals; a bonus game configured to award a bonus payout more rewarding than the payout in the base game; a bonus payout indicator that displays the bonus payout; and paths, respectively corresponding to the gaming terminals, including light emitting portions arranged to form a channel extending from a position corresponding to each gaming terminal to the bonus payout indicator. In each gaming terminal, the base game is run independently from the other gaming terminals. The bonus game is run. A random number of the light emitting portions are activated toward the bonus payout indicator in a path corresponding to a gaming terminal in which a predetermined winning is met, every time the predetermined winning is met in the gaming terminals. The bonus payout is awarded in a gaming terminal corresponding to a path in which the light emitting portions turned active up to the bonus payout indicator.

摘要翻译： 游戏机包括：基本游戏; 游戏终端; 奖励游戏被配置为奖励比基本游戏中的支付更有奖励的奖金支付; 显示奖金支出的奖金支付指标; 以及分别对应于游戏终端的路径，包括布置成形成从对应于每个游戏终端的位置延伸到奖励支付指示符的通道的发光部分。 在每个游戏终端中，基本游戏独立于其他游戏终端运行。 奖金游戏运行。 每当在游戏终端中满足预定的胜利时，随机数量的发光部分朝向与满足预定获胜的游戏终端相对应的路径中的奖励支付指示符被激活。 在与发光部分变为激活的路径相对应的奖励支付指示符的游戏终端中奖励奖金。

公开(公告)号：US08210328B2

公开(公告)日：2012-07-03

申请号：US12606907

申请日：2009-10-27

申请人： Masatoshi Kano ,  Kunio Ishihara ,  Haruhisa Baba ,  Keisuke Seto ,  Hitoshi Ikeuchi ,  Yoichi Kato

发明人： Masatoshi Kano ,  Kunio Ishihara ,  Haruhisa Baba ,  Keisuke Seto ,  Hitoshi Ikeuchi ,  Yoichi Kato

IPC分类号： F16D65/12

CPC分类号： F16D65/12 ,  F16D2065/1316 ,  F16D2065/1328 ,  F16D2065/1368 ,  F16D2065/1392

摘要： A disc rotor includes a sliding portion, a hat portion, and a connecting unit connecting the sliding portion and the hat portion. The connecting unit includes a washer arranged between the radially inner portion of the sliding portion and the radially outer portion of the hat portion, and a connecting pin having a head portion, having a shaft portion inserted through a first through-hole formed at the sliding portion, the washer and a second through-hole formed at the hat portion in an axial direction of the rotor, and riveted at an end portion of the shaft portion so as to integrally fasten the sliding portion, the washer and the hat portion. A riveted portion of the connecting pin is formed into a taper shape, and an outer circumferential surface of the riveted portion contacts and engages a tapered surface formed at the second through-hole of the hat portion.

摘要翻译： 碟形转子包括滑动部分，帽部分和连接滑动部分和帽部分的连接单元。 连接单元包括设置在滑动部分的径向内部部分和帽部分的径向外部之间的垫圈和具有头部的连接销，该头部具有穿过形成在滑动件处的第一通孔插入的轴部分 所述垫圈和形成在所述帽部的转子的轴向方向上的第二通孔，并且在所述轴部的端部铆接，从而整体地固定所述滑动部，所述垫圈和所述帽部。 连接销的铆接部形成为锥形，铆接部的外周面与形成在帽部的第二贯通孔的锥面接触。