利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

88 条记录 (耗时 0.038 秒)

    Intermittent claudication therapeutic drugs comprising pyrroloazepines
    51.
    发明授权
    Intermittent claudication therapeutic drugs comprising pyrroloazepines 失效
    间歇性跛行治疗药物，包括吡咯并氮

    公开(公告)号：US06288056B1

    公开(公告)日：2001-09-11

    申请号：US09673514

    申请日：2000-10-17

    申请人： Atsuto Ogata ,  Norio Inomata ,  Akira Mizuno

    发明人： Atsuto Ogata ,  Norio Inomata ,  Akira Mizuno

    IPC分类号： A61K3155

    CPC分类号： A61K31/55 ,  A61K31/496

    摘要： A method of treating or improving intermittent claudication, which comprises administering, to a patient with intermittent claudication, a pyrroloazepine derivative or a pharmacologically acceptable salt thereof, said pyrroloazepine derivative being represented by the following formula (I): wherein the dotted line indicates existence or nonexistence of a bond; when the bond of the dotted line exists, X does not exist, and, when the bond of the dotted line does not exist, X represents a hydrogen atom, a hydroxy group or a group OR1 in which R1 represents a substituted or unsubstituted alkyl group; Y represents a linear or branched, substituted or unsubstituted alkyl group; Z1 and Z2 are the same or different and each independently represent a hydrogen atom, a hydroxy group or a halogen atom; and W represents a hydrogen atom or a methyl group.

    摘要翻译： 一种治疗或改善间歇性跛行的方法，其包括对间歇性跛行的患者施用吡咯并氮衍生物或其药理学上可接受的盐，所述吡咯并氮衍生物由下式（I）表示：其中虚线表示存在或 不存在债券; 当存在虚线的键时，X不存在，并且当虚线的键不存在时，X表示氢原子，羟基或其中R 1表示取代或未取代的烷基的基团OR 1 ; Y表示直链或支链的取代或未取代的烷基; Z 1和Z 2相同或不同，各自独立地表示氢原子，羟基或卤素原子; W表示氢原子或甲基。

    Pyrroloazepine derivatives
    52.
    发明授权
    Pyrroloazepine derivatives 失效
    吡咯并氮衍生物

    公开(公告)号：US06258805B1

    公开(公告)日：2001-07-10

    申请号：US09312713

    申请日：1999-05-17

    申请人： Akira Mizuno ,  Makoto Shibata ,  Tomoe Iwamori ,  Tetsuo Shimamoto ,  Kyoko Nakanishi ,  Norio Inomata

    发明人： Akira Mizuno ,  Makoto Shibata ,  Tomoe Iwamori ,  Tetsuo Shimamoto ,  Kyoko Nakanishi ,  Norio Inomata

    IPC分类号： A61K3155

    CPC分类号： C07D487/04 ,  C07D207/34

    摘要： A method for treating a circulatory disease or condition in a mammal, which entails administering to the mammal an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt thereof: wherein the ring P represented by  is a pyrrole ring having the following structure: wherein R1 represents C1-C8 alkyl, C3-C8 cycloalkyl, C4-C8 cycloalkyl-alkyl, C6-C14 aryl or C7-C22 aralkyl, which are optionally substituted; and R2 represents H or C1-C8 alkyl, which is optionally substituted; the dashed line indicates the presence or absence of a bond; and, when the bond is present, Z2 is not present and Z1 represents H, but, when the bond is absent, Z1 and Z2 are both H; Z1 represents H and Z2 represents a group OR3, in which R3 represents H, C1-C8 alkyl, or C7-C22 aralkyl, which are optionally substituted; Z1 and Z2 both represent groups SR4, in which R4 represents C1-C8 alkyl or C7-C22 aralkyl, which are optionally substituted; or Z1 and Z2 are combined together to represent O, a group NOR5, in which R5 represents H, or C1-C8 alkyl or C2-C3 alkylenedithio, which are optionally substituted; A represents alkylene, alkenylene or alkynylene; and Y represents a group in which W is CH, C═ or N, m is for 0 or 1, n is for 1, 2 or 3, G is O, S, C═O, sulfinyl, sulfonyl, alkylene, alkenylene or acetal; E1 and E2 is H or C1-C8 alkyl; and D represents an aromatic hydrocarbon or an aromatic heterocyclic ring. The compound (I) has strong serotonin-2 receptor antagonistic action and low toxicity and less side effects, and is therapeutically useful in the treatment of circulatory diseases and/or conditions related thereto.

    摘要翻译： 一种用于治疗哺乳动物的循环系统疾病或病症的方法，其需要向哺乳动物施用有效量的式（I）化合物或其药学上可接受的盐：其中由表示的环P是具有以下基团的吡咯环 结构：其中R 1表示任选取代的C 1 -C 8烷基，C 3 -C 8环烷基，C 4 -C 8环烷基 - 烷基，C 6 -C 14芳基或C 7 -C 22芳烷基; 并且R 2表示H或被任选取代的C 1 -C 8烷基; 虚线表示存在或不存在键; 当存在键时，Z 2不存在，Z1表示H，但不存在键时，Z 1和Z 2均为H; Z1表示H，Z2表示OR3，其中R3表示H，任选取代的C 1 -C 8烷基或C 7 -C 22芳烷基; Z 1和Z 2均表示SR 4，其中R 4表示任选取代的C 1 -C 8烷基或C 7 -C 22芳烷基; 或Z 1和Z 2组合在一起表示O，其中R 5表示H的基团NOR 5或任选被取代的C 1 -C 8烷基或C 2 -C 3亚烷基二硫基; A表示亚烷基，亚烯基或亚炔基; 并且Y表示W为CH，C =或N的基团，m为0或1，n为1,2或3，G为O，S，C = O，亚磺酰基，磺酰基，亚烷基，亚烯基或亚磺酰基 乙缩醛 E1和E2是H或C1-C8烷基; D表示芳族烃或芳香族杂环。 化合物（I）具有强的5-羟色胺-2受体拮抗作用和低毒性和较少的副作用，并且在治疗循环系统疾病和/或与之有关的病症中是治疗上有用的。

    Liquid fuel combustion type infrared ray irradiating apparatus
    56.
    发明授权
    Liquid fuel combustion type infrared ray irradiating apparatus 失效
    液体燃料燃烧式红外线照射装置

    公开(公告)号：US5044353A

    公开(公告)日：1991-09-03

    申请号：US543155

    申请日：1990-06-25

    申请人： Akira Mizuno ,  Hiroshi Komai ,  Toshio Ina ,  Tadao Suzuki

    发明人： Akira Mizuno ,  Hiroshi Komai ,  Toshio Ina ,  Tadao Suzuki

    IPC分类号： F23C5/00 ,  F24C5/00 ,  F24C5/08 ,  F24C5/20

    CPC分类号： F24C5/08

    摘要： A liquid fuel combustion type infrared ray irradiating apparatus includes a base having a generally rectangular-shaped framework, each corner of which is provided with a wheel, a fuel tank fixed to the base, and a pump disposed on the base and adapted to pump fuel from the fuel tank. A combustion chamber is connected to a burner which receives fuel from the pump for combustion. An irradiation pipe is connected to the combustion chamber for guiding combustion gas from the combustion chamber into an upper chimney, receiving heat from the combustion gas, and irradiating infrared rays. Reflecting plates are disposed to forwardly reflect rearwardly directed radiant heat which has been radiated from the irradiation pipe.

    Flat panel image display unit
    57.
    发明授权
    Flat panel image display unit 失效
    平板图像显示单元

    公开(公告)号：US07456807B2

    公开(公告)日：2008-11-25

    申请号：US10548717

    申请日：2004-05-27

    申请人： Akira Mizuno ,  Masayuki Esaki

    发明人： Akira Mizuno ,  Masayuki Esaki

    IPC分类号： G09G3/28

    CPC分类号： H04N5/64 ,  H04N5/70 ,  Y10S345/901

    摘要： A flat panel image display unit such as a plasma display device is provided having a structure of signal input terminals that is adaptable flexibly to a plurality of different kinds of video signals. The image display unit includes a flat display panel, a display drive circuit block, an input signal circuit block connected between the display drive circuit block and an external apparatus for outputting a video signal, and an enclosure for housing the above components. The input signal circuit block includes a plurality of different kinds of board blocks provided replaceably according to a plurality of different forms of signals. A casing member is placed inside the enclosure and is provided with an insertion opening for accepting insertion of any of the board blocks. A guide rail is for positioning the board block to a predetermined position. The plurality of guide rails are provided according to the board block of a smallest unit size.

    摘要翻译： 提供了诸如等离子体显示装置的平板图像显示单元，其具有可灵活地适应于多种不同种类的视频信号的信号输入端的结构。 图像显示单元包括平面显示面板，显示驱动电路块，连接在显示驱动电路块和用于输出视频信号的外部设备之间的输入信号电路块，以及用于容纳上述组件的外壳。 输入信号电路块包括根据多种不同形式的信号可替换地提供的多种不同种类的板块。 外壳部件放置在外壳的内部，并且设置有用于接受任何板块的插入的插入开口。 导轨用于将板块定位到预定位置。 根据最小单位尺寸的板块提供多个导轨。

    Method of Sterilization and Apparatus Therefore
    58.
    发明申请
    Method of Sterilization and Apparatus Therefore 有权
    因此，灭菌方法

    公开(公告)号：US20080233002A1

    公开(公告)日：2008-09-25

    申请号：US10594387

    申请日：2005-03-29

    申请人： Akira Mizuno ,  Hiroyuki Yuyama ,  Yoshinori Shirahara

    发明人： Akira Mizuno ,  Hiroyuki Yuyama ,  Yoshinori Shirahara

    IPC分类号： A61L2/14 ,  A61L2/20

    CPC分类号： A61L2/208 ,  A61L2/14 ,  A61L2/202 ,  A61L2202/24

    摘要： The present invention provides a harmless sterilization method and sterilization apparatus which provide adequate sterilization effects without residual gas. The method comprises: a sterilization step in which a chamber containing an object to be sterilized is depressurized; a hydrogen peroxide supply step in which hydrogen peroxide is supplied into the chamber; an ozone supply step in which ozone is supplied into the chamber; a sterilization step in which the hydrogen peroxide and ozone supplied inside the chamber are dispersed to sterilize the object to be sterilized; an exhaust step in which gas inside the chamber is exhausted; and a plasma generation step in which plasma is generated inside the chamber to break down hydrogen peroxide and ozone remaining near the object to be sterilized, and radicals which promote sterilization are generated.

    摘要翻译： 本发明提供了无残留气体提供足够灭菌效果的无害灭菌方法和灭菌装置。 该方法包括：灭菌步骤，其中包含待消毒物体的室被减压; 过氧化氢供给步骤，其中将过氧化氢供给到室中; 将臭氧供给到所述室内的臭氧供给步骤; 灭菌步骤，其中分散在室内的过氧化氢和臭氧被分散以消毒待消毒的物体; 废气步骤，其中室内的气体被耗尽; 以及等离子体产生步骤，其中在腔室内产生等离子体以分解残留在待消毒物体附近的过氧化氢和臭氧，并产生促进灭菌的自由基。

    Plasma display apparatus
    60.
    发明申请
    Plasma display apparatus 失效

    公开(公告)号：US20060152909A1

    公开(公告)日：2006-07-13

    申请号：US11364338

    申请日：2006-03-01

    申请人： Tomihide Nomoto ,  Kazunobu Kojima ,  Akira Mizuno

    发明人： Tomihide Nomoto ,  Kazunobu Kojima ,  Akira Mizuno

    IPC分类号： H05K5/02 ,  H05K9/00

    CPC分类号： H05K5/02

    摘要： A plasma display apparatus is equipped with a signal input terminal responsive to a user's application. The plasma display apparatus includes a panel including a pair of substrates, wherein at least one of the substrates is transparent. The substrates are placed opposite to each other to form a discharge space in between, and electrodes are provided to the substrate. The plasma display apparatus also includes a display driving circuit block, disposed on a chassis and equipped with at least one signal inputting connector which applies a signal to the panel to perform displaying, and an input signal circuit block detachable to the signal inputting connector of the display driving circuit block.