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51.发明授权
公开(公告)号：US5705189A
公开(公告)日：1998-01-06
申请号：US521738
申请日：1995-08-31
申请人： Klaus Lehmann , Werner Hoess
发明人： Klaus Lehmann , Werner Hoess
CPC分类号： A61K9/2846 , A61K9/4816
摘要： Thermoplastic materials which comprise a copolymer of (A) 16 to 40 wt % of acrylic and/or methacrylic acid; (B) 30 to 80 wt % of methyl acrylate; and (C) 0 to 40 wt % of another alkyl ester of acrylic and/or methacrylic acid and perhaps conventional auxiliaries for drug coatings are suitable for the production of drug coatings which are soluble in intestinal juices, such as tablet coatings, dies, films, capsules, or multipart dosage units.
摘要翻译： 包含（A）16〜40重量％的丙烯酸和/或甲基丙烯酸的共聚物的热塑性材料; （B）30〜80重量％的丙烯酸甲酯; 和（C）0至40重量％的丙烯酸和/或甲基丙烯酸的另一烷基酯以及可能用于药物涂料的常规助剂适用于生产可溶于肠液的药物包衣，例如片剂包衣，模具，薄膜 ，胶囊或多剂量单位。
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52.发明授权Process for the short-time treatment of a plastic melt with a liquid treatment agent and the plastic thus produced 失效用液体处理剂短时间处理塑料熔体的方法和由此生产的塑料
公开(公告)号：US5548033A
公开(公告)日：1996-08-20
申请号：US379999
申请日：1995-01-27
CPC分类号： B29C47/527 , B29C47/0009
摘要： A plastic melt is treated for a short-time with a liquid treatment agent under pressure, it is divided into defined subquantities, individual subquantities are brought into contact with a treatment agent and combined for a residence time of less than one second with portions of at least one other subquantity, and portions of the mixture thus formed are separated and combined with another subquantity; the steps of dividing and combining the mixture are repeated several times at intervals of less than one second until an intimate mixture of the plastic melt and the treatment agent has formed, allowing the preparation of especially homogeneously structured thermoplastic materials, e.g., poly(methacrylalkylimide) plastics, which are compatible with poly(methyl methacrylate).
摘要翻译： 塑料熔体在压力下用液体处理剂短时间处理，分为限定的量级，各个次要物质与处理剂接触并结合使用少于1秒的停留时间，其中部分 至少一个其他的次数，并且如此形成的混合物的部分与另一个次级分离并组合; 将混合物分离和组合的步骤以小于1秒的间隔重复数次，直到形成塑料熔体和处理剂的紧密混合物，允许制备特别均匀结构的热塑性材料，例如聚（甲基丙烯酸烷基酯酰亚胺） 塑料，其与聚（甲基丙烯酸甲酯）相容。
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