-
公开(公告)号：US4261532A
公开(公告)日：1981-04-14
申请号：US83462
申请日：1979-10-10
摘要： A bobbin carrier includes a rectangular frame having adjustable support shafts mounted at the corners thereof which, in turn, individually adjustably support brackets, each of which includes means for adjustably and slidably positioning thereon a pair of support rods adapted to receive large yarn bobbins. Yarn bobbins supported upon the carrier are selectively aligned, and spaced uniform distances from generally centrally located first guide means resulting in uniformity of feed of yarns to a machine which utilizes the yarns. Bobbins may be replaced by slidably retracting the support rods relative to the bobbin and the brackets.
摘要翻译： 筒管架包括：矩形框架，其具有安装在其角部的可调节的支撑轴，该矩形框架又独立地可调节地支撑支架，每个支架包括用于可调节地和可滑动地定位在其上的适于接收大的纱线筒的一对支撑杆的装置。 支撑在载体上的纱线线轴被选择性地对齐，并且与通常位于中心的第一引导装置间隔开均匀的距离，导致纱线进给使用纱线的机器的均匀性。 可以通过相对于线轴和支架滑动地缩回支撑杆来代替线轴。
-
公开(公告)号：US4189372A
公开(公告)日：1980-02-19
申请号：US907933
申请日：1978-05-22
CPC分类号： C10G1/006
摘要： This invention relates to a process for producing coal derived, hydrogen-rich donor fractions from fractions of coal liquefaction products for use in the hydroconversion of coal. Coal liquefaction products are subjected to a critical solvent deashing process to produce various deashed coal fractions which can only be obtained by practicing that process. Thereafter, the various deashed coal fractions are subjected to hydrogen addition to produce heretofore unavailable hydrogen-rich donor fractions. These hydrogen-rich donor fractions may be recycled to supplant a portion of the liquefaction process solvent or blended with other fractions produced by the deashing process to provide improved fuel products.
摘要翻译： 本发明涉及从用于煤的加氢转化的煤液化产物的馏分中生产来自煤的富氢供体部分的方法。 对煤液化产物进行临界溶剂除冰过程，以生产各种除渣的煤馏分，只能通过实践该方法获得。 此后，将各种除渣煤馏分进行氢加成以产生迄今为止不可获得的富含氢的供体部分。 这些富氢的供体部分可以被再循环以取代液化过程溶剂的一部分或与通过除冰过程产生的其它馏分混合以提供改进的燃料产物。
-
53.发明授权
公开(公告)号：US4164466A
公开(公告)日：1979-08-14
申请号：US888284
申请日：1978-03-20
CPC分类号： C10G1/045
摘要： A coal deashing process wherein a feed mixture comprising soluble coal products, insoluble coal products and solvent is separated in a first separation zone into a first heavy phase and a first light phase comprising soluble coal products, solvent and some insoluble coal products. The first light phase is withdrawn and introduced into a second separation zone wherein it separates into a second heavy phase comprising insoluble coal products, soluble coal products and some solvent and a second light phase comprising soluble coal products and solvent. The second heavy phase is withdrawn and at least a portion is recycled to the first separation zone to increase the yield of separable soluble coal products ultimately recovered by the process. In alternate embodiments, additional solvent can be added to the first light phase before introduction into the second separation zone or the recycled portion of the second heavy phase may be introduced into a treatment zone before reintroduction into the first separation zone. The treatment zone effects an increase in the molecular weight of at least a portion of the recycled second heavy phase which facilitates subsequent separation in the first separation zone.
摘要翻译： 一种煤脱渣方法，其中将包含可溶性煤产物，不溶性煤产物和溶剂的进料混合物在第一分离区中分离成第一重相和包含可溶性煤产物，溶剂和一些不溶性煤产品的第一轻相。 将第一轻相取出并引入第二分离区，其中其分离成包含不溶性煤产物，可溶性煤产物和一些溶剂的第二重相，以及包含可溶性煤产物和溶剂的第二轻相。 第二重相被取出，并且至少一部分被再循环到第一分离区，以增加最终通过该方法回收的可分离的可溶性煤产品的产率。 在替代实施方案中，可以在引入第二分离区之前将另外的溶剂加入到第一轻相中，或者可以在重新引入第一分离区之前将第二重相的再循环部分引入处理区。 处理区域使再循环的第二重质相的至少一部分的分子量增加，这有助于在第一分离区域中随后的分离。
-
公开(公告)号：US4119816A
公开(公告)日：1978-10-10
申请号：US746719
申请日：1976-12-02
申请人： Robert E. Davis
发明人： Robert E. Davis
CPC分类号： H01H13/70
摘要： A cross connect panel having a switchable slider assembly for positive engagement and disengagement of the loads to the supply buses. A resilient detent mechanism is provided for positive indexing of the slider assembly in alignment position with the various supply buses. The parallel supply buses are held in place by a system of bus holders and interlocking spacers and the bus bar assembly is held together by bolts through the interlocking spacers, thereby avoiding the necessity of drilling bolt holes in the bus bars and providing proper insulation therefor.
摘要翻译： 具有可切换滑块组件的交叉连接面板，用于将负载正向接合和分离到供应总线。 提供弹性制动机构，用于使滑块组件与各种供应总线对准的位置正向分度。 并联供电总线通过总线保持器和互锁间隔件的系统保持在适当位置，母线组件通过螺栓通过互锁间隔件保持在一起，从而避免了在母线中钻螺栓孔并提供适当的绝缘。
-
55.发明授权
公开(公告)号：US4087384A
公开(公告)日：1978-05-02
申请号：US752319
申请日：1976-12-20
申请人： Robert E. Davis
发明人： Robert E. Davis
CPC分类号： B01D53/944 , B01J23/44
摘要： A method of lowering undesirable vehicle exhaust emissions includes preparing a catalyst for use in the exhaust stream of the vehicle. The method includes impregnating one group of alumina substrates with platinum, impregnating another group of alumina substrates with palladium, and the mixing the first and second groups of impregnated substrates.
摘要翻译： 减少不期望的车辆废气排放的方法包括制备用于车辆排气流中的催化剂。 该方法包括用铂浸渍一组氧化铝衬底，用钯浸渍另一组氧化铝衬底，并混合第一组和第二组浸渍衬底。
-
56.发明申请SELECTIVE SEROTONIN 2A/2C RECEPTOR INVERSE AGONISTS AS THERAPEUTICS FOR NEURODEGENERATIVE DISEASES 有权选择性丝氨酸蛋白酶2A / 2C受体反转激动剂作为神经病变性疾病的治疗剂公开(公告)号：US20120277221A1
公开(公告)日：2012-11-01
申请号：US13539011
申请日：2012-06-29
IPC分类号： A61K31/445 , A61K31/519 , A61P25/00 , A61K31/551
CPC分类号： A61K31/4468 , A61K9/20 , A61K31/194 , A61K45/06 , C07C59/255 , C07D211/58 , A61K2300/00
摘要： Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.
摘要翻译： 与式（I）化合物（一种新型和选择性的5HT2A / 2C受体反向激动剂）的行为药理学数据证明了在精神病和运动障碍模型中的体内功效。 这包括逆转MK-801诱导的运动行为的活动，表明该化合物可能是MPTP灵长类运动障碍模型中有效的抗精神病药和活性，表明作为抗运动障碍剂的功效。 这些数据支持5HT2A / 2C受体反向激动作用可能赋予人类抗精神病和抗运动障碍功效的假说，并表明使用式（I）化合物和相关药物作为帕金森病，相关人类神经变性疾病的新疗法， 和精神病。
-
57.发明申请公开(公告)号：US20100227886A1
公开(公告)日：2010-09-09
申请号：US12759664
申请日：2010-04-13
IPC分类号： A61K31/4468 , A61P25/18
CPC分类号： A61K31/4468 , A61K9/20 , A61K31/194 , A61K45/06 , C07C59/255 , C07D211/58 , A61K2300/00
摘要： Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.
-
58.发明申请Selective Serotonin 2A/2C Receptor Inverse Agonists as Therapeutics for Neurodegenerative Diseases 有权选择性5-羟色胺2A / 2C受体反向激动剂作为治疗神经退行性疾病公开(公告)号：US20100227885A1
公开(公告)日：2010-09-09
申请号：US12759662
申请日：2010-04-13
IPC分类号： A61K31/4468 , A61P25/28
CPC分类号： A61K31/4468 , A61K9/20 , A61K31/194 , A61K45/06 , C07C59/255 , C07D211/58 , A61K2300/00
摘要： Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.
摘要翻译： 与式（I）化合物（一种新型和选择性的5HT2A / 2C受体反向激动剂）的行为药理学数据证明了在精神病和运动障碍模型中的体内功效。 这包括逆转MK-801诱导的运动行为的活动，表明该化合物可能是MPTP灵长类运动障碍模型中有效的抗精神病药和活性，表明作为抗运动障碍剂的功效。 这些数据支持5HT2A / 2C受体反向激动作用可能赋予人类抗精神病和抗运动障碍功效的假说，并表明使用式（I）化合物和相关药物作为帕金森病，相关人类神经变性疾病的新疗法， 和精神病。
-
59.发明授权Apparatus and method to transfer data from a tire pressure monitor tool to a remote output device such as a printer 有权将数据从轮胎压力监测工具传送到诸如打印机的远程输出装置的装置和方法公开(公告)号：US07589619B2
公开(公告)日：2009-09-15
申请号：US11650513
申请日：2007-01-08
IPC分类号： B60C23/00
CPC分类号： B60C23/0408 , B60C23/0479
摘要： A tire pressure monitoring tool transmits a triggering signal to a tire sensor; receives a reporting signal from the tire sensor; extracts data from the reporting signal; stores the extracted data; and transmits the stored data to an external device. The transmitted stored data is in a predetermined order, and in a text format.
摘要翻译： 轮胎压力监测工具将触发信号传送到轮胎传感器; 从轮胎传感器接收报告信号; 从报告信号中提取数据; 存储提取的数据; 并将存储的数据发送到外部设备。 所发送的存储数据是以预定的顺序和文本格式。
-
60.发明申请公开(公告)号：US20090209525A1
公开(公告)日：2009-08-20
申请号：US12340393
申请日：2008-12-19
IPC分类号： A61K31/551 , C12Q1/68 , G01N33/53 , A61K31/538 , A61K31/445 , A61K31/195 , A61K31/46 , A61K31/4439 , A61K31/4025
CPC分类号： G01N33/9406 , G01N2500/04
摘要： A method developed to identify receptor modulators, involving providing a mutant receptor, wherein said mutant receptor has a mutation that alters the activity of said mutant receptor compared to a wild type receptor; contacting said mutant receptor with a candidate compound; and determining whether said candidate compound modulates the activity of said mutant receptor.
摘要翻译： 一种开发用于鉴定受体调节剂的方法，涉及提供突变体受体，其中所述突变体受体具有与野生型受体相比改变所述突变受体活性的突变; 使所述突变体受体与候选化合物接触; 以及确定所述候选化合物是否调节所述突变受体的活性。
-
-
-
-
-
-
-
-
-
搜索结果
105 条记录 (耗时 0.038 秒)
