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公开(公告)号:US11250964B2
公开(公告)日:2022-02-15
申请号:US16504760
申请日:2019-07-08
发明人: Jozef Comor , Jean-Michel Geets , Benoît Nactergal
摘要: A capsule for the transfer of a target material in a conveying system between a target irradiation station and a collecting station comprising: a beamline channel for the passage of an energetic beam irradiating the target material, a target holder holding the target material or a substrate backing the target material at a glancing angle with respect to the beamline channel axis, a degrader foil positioned across the beamline channel for degrading an energy of the energetic beam upstream of the target material, a target cooling inlet and a target cooling outlet for passage of a cooling fluid in a target cooling duct in a vicinity of the target holder such that the target material can be cooled during an irradiation, and a degrader foil cooling inlet and a degrader foil cooling outlet for passage of a cooling gas in a vicinity of the degrader foil.
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公开(公告)号:US20210402213A1
公开(公告)日:2021-12-30
申请号:US17362471
申请日:2021-06-29
发明人: Rudi LABARBE , Lucian HOTOIU , Arnaud PIN
IPC分类号: A61N5/10
摘要: A treatment planning system for generating a plan for treatment with charged particles beams, of a target tissue including tumoral cells enclosed within a peripheral surface, which is surrounded by healthy cells the plan including N fractions of irradiation including irradiation of volumes including tumoral cells and healthy cells at a conventional dose deposition rate, irradiation of volumes including tumoral cells and healthy cells at an ultra-high dose deposition rate, wherein an equivalent healthy fraction dose does not exceed a maximum equivalent healthy fraction dose for preserving the healthy cells after each fraction, and a total equivalent healthy dose delivered to and cumulated in a volume of a healthy tissue at the end of N fractions does not exceed a maximum equivalent healthy dose for preserving the healthy cells at the end of the N fractions.
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公开(公告)号:US11045666B2
公开(公告)日:2021-06-29
申请号:US16654049
申请日:2019-10-16
发明人: Vincent Bossier , Yves Claereboudt , Guillaume Janssens , Olivier De Wilde , David Vangeenberghe
IPC分类号: A61N5/10
摘要: A particle therapy system includes a particle accelerator for generating a charged particle beam, a beam delivery device, a beam transport system for transporting the beam from the particle accelerator to the beam delivery device, and a supporting device for supporting a subject. The beam delivery device is rotatable around the target and with respect to the supporting device, so as to be able to deliver the beam to the target according to a plurality of irradiation angles. The system also includes a controller configured to make the beam delivery device rotate at a beam-on speed and meanwhile to irradiate the target with the beam. The controller is configured to make the beam delivery device rotate at at least two different beam-on speeds with respect to the supporting device, a first speed corresponding to a first irradiation angle and a second speed corresponding to a second irradiation angle.
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公开(公告)号:US10779433B2
公开(公告)日:2020-09-15
申请号:US15903609
申请日:2018-02-23
发明人: Michel Abs , Denis Joassin
摘要: In accordance with the embodiments of the present disclosure, a rack comprising a frame having first vertical posts on a first side and second vertical posts on a second side, wherein the first side is opposite the second side, between which a plurality of RF amplifier modules are mounted, is provided. The RF power outputs of the RF amplifier modules are connected to inputs of an RF power combiner to deliver a combined RF power output. The RF power combiner is arranged at least partially in at least one of a first volume between the first vertical posts of the frame or a second volume between the second vertical posts of the frame, thereby reducing a footprint of the rack.
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公开(公告)号:US20200090379A1
公开(公告)日:2020-03-19
申请号:US16471842
申请日:2017-12-20
摘要: The invention relates to off-center detector 3D X-ray or proton radiography reconstruction. Redundancy weighting with a steep weighting function around the iso-axis typically leads to artifacts in the reconstruction, for example, if inconsistencies between two nominal redundant projections occur, e.g. due to slightly incorrect detector calibration or scatter correction, etc. With the present invention, an approach is presented for overcoming or mitigating these problems.
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公开(公告)号:US10383206B1
公开(公告)日:2019-08-13
申请号:US16213886
申请日:2018-12-07
摘要: A cyclotron for accelerating charged particles includes: a first and second superconducting main coils arranged parallel to one another on either side of a median plane; and at least a first and second field bump modules arranged on either side of the median plane, and extending circumferentially over a common azimuthal angle for creating a local magnetic field bump in the main magnetic field. Each of the field bump modules includes at least one superconducting bump coil locally generating a broad magnetic field bump having a bell-shape defined by a first gradient of the z-component in a radial direction, r. Each of the field bump modules further includes at least one superconducting bump shaping unit positioned such as to locally steepen the first gradient produced by the at least one superconducting bump coil, when said at least one superconducting bump shaping unit is activated.
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公开(公告)号:US20190151677A1
公开(公告)日:2019-05-23
申请号:US16042928
申请日:2018-07-23
发明人: Yves Jongen
摘要: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a gantry for delivering particle beams which comprises means to analyse the incoming beam. Means are integrated into the gantry to limit the momentum spread of the beam and/or the emittance of the beam.
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公开(公告)号:US10278277B2
公开(公告)日:2019-04-30
申请号:US15594534
申请日:2017-05-12
发明人: Willem Kleeven , Szymon Zaremba
IPC分类号: H05H13/00 , H05H9/00 , H05H7/10 , H05H7/04 , H01F7/02 , H05H7/00 , H05H13/08 , H01F3/10 , H01F7/20
摘要: The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges, and a peripheral surface extending from the upper peripheral edge to a lower peripheral line. The upper peripheral edge of at least one hill sector may further include a concave portion with respect to the central axis defining a recess extending at least partially over a portion of the peripheral surface of the corresponding hill sector.
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公开(公告)号:US10249400B2
公开(公告)日:2019-04-02
申请号:US15805647
申请日:2017-11-07
摘要: An electron accelerator comprising a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further comprises a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further comprises a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further comprises a first half shell, a second half shell, and a central ring element.
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公开(公告)号:US10195461B2
公开(公告)日:2019-02-05
申请号:US15835980
申请日:2017-12-08
发明人: Carolina Fuentes
摘要: A particle therapy apparatus for irradiating a diseased part of a patient's eye with a charged particle beam comprises a particle accelerator to generate the particle beam, a movable irradiation nozzle adapted to direct the particle beam towards the patient's eye according to different beam directions, and a patient support adapted to receive and hold the patient in a treatment position. The apparatus further comprises a pencil beam scanning subsystem configured to scan the particle beam over the diseased part of the patient's eye, a movable marker arranged in such a way that it is visible by the patient while he is in the treatment position and a controller configured to move said marker to a pre-determined and patient-specific position before starting an irradiation of the eye with the particle beam.
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