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公开(公告)号:US20220226299A1
公开(公告)日:2022-07-21
申请号:US17599271
申请日:2020-03-26
Applicant: NIPPON CHEMIPHAR CO., LTD. , UTI LIMITED PARTNERSHIP , KINKI UNIVERSITY
Inventor: Gerald W. ZAMPONI , Vinicius de Maria GADOTTI , Atsufumi KAWABATA , Toru OGAWA , Hiroto TANAKA , Isao OOI , Daisuke SAITO , Kohei HAYASHIDA , Kohei YAMAMOTO
IPC: A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/427 , A61K31/497 , A61K31/437 , A61K31/541 , A61K31/5377 , A61K31/4184 , A61K31/501 , A61K31/4427 , A61K31/438 , A61K31/402 , A61P17/04
Abstract: A medicament for treating or preventing pruritus is provided. For the medicament for treating or preventing pruritus, a compound having a blocking action on Cav3.2T-type calcium channels represented by General Formulas (I) to (VI), a tautomer of the compound, a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is used as an active ingredient.
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公开(公告)号:US11376560B2
公开(公告)日:2022-07-05
申请号:US16419851
申请日:2019-05-22
Applicant: UTI Limited Partnership
Inventor: Davood Karami , S. Toufigh Bararpour , Nader Mahinpey
IPC: B01J20/08 , C01F7/021 , B01J20/32 , B01J20/06 , B01J20/04 , B01J20/28 , B01D53/04 , F23C13/08 , C01F7/448
Abstract: The invention provides highly reactive nano-sized alumina particle compositions, including alumina compositions with a BET surface areas on the order of 2000 m2/g. Also disclosed are impregnated alumina supports comprising materials that are metal oxides or carbonates. Methods for the synthesis and fabrication of these compositions are provided, along methods for the use of these compositions as sorbents.
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公开(公告)号:US11338024B2
公开(公告)日:2022-05-24
申请号:US16132000
申请日:2018-09-14
Applicant: UTI Limited Partnership
Inventor: Pedro Santamaria
Abstract: This disclosure provides methods of making functionalized PEG iron oxide nanoparticles.
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公开(公告)号:US20220011337A1
公开(公告)日:2022-01-13
申请号:US17298647
申请日:2020-01-24
Applicant: UTI LIMITED PARTNERSHIP
Inventor: Ahmed YOUSSEF , Naser EL-SHEIMY
IPC: G01P15/093 , G01P15/03 , G01P15/18
Abstract: Systems and methods relating to sensors for measuring acceleration. Two attached containers are each filled with different liquids. At each junction of the two liquids, an indicator is placed. When acceleration forces are applied to the sensor, the indicator moves when the boundary between the two liquids similarly move. The amount of movement of the boundary and of the indicator is proportional to the amount of acceleration for applied. A tracking subsystem tracks the position of the indicator and, by determining the amount of movement of the indicator, the amount of acceleration force applied can be calculated. The indicator can be a particle or it can be a beam-like element that deflects when the boundary between the two liquids move.
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公开(公告)号:US20210372258A1
公开(公告)日:2021-12-02
申请号:US17334994
申请日:2021-05-31
Applicant: UTI LIMITED PARTNERSHIP
Abstract: System and method for guiding a drill using a subsurface model generated by successive full waveform inversions (FWI) on surface data and seismic-while-drilling (SWD) data. A server receives surface data from at least one surface sensor that records elastic energy radiated from surface seismic source and SWD data from at least one surface or at least one subsurface crosswell sensor (i.e., deployed in a nearby well). The server also receives top-drive measurements. A drillbit source signature estimation is performed, on the SWD data, by the server by blind deconvolution or by using drill string modeling and top-drive measurements. The server then performs FWI on the surface data by using the background subsurface velocity obtained by kinematic analysis of surface seismic data, to obtain an updated approximation of the subsurface velocity. The new approximation along with the drillbit source signature is then used when performing FWI on the SWD data.
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公开(公告)号:US20210246776A1
公开(公告)日:2021-08-12
申请号:US17055825
申请日:2019-05-15
Applicant: UTI LIMITED PARTNERSHIP , ASSOCIATION POUR LA RECHERCHE ET DÉVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS , NORCE NORWEGIAN RESEARCH CENTRE AS
Inventor: Roman Jgorevich SHOR , Florent DI MEGLIO , Ulf Jakob Flo AARSNES
Abstract: A system for controlling a drill string located in a borehole. The drill string has a top portion and a bottom hole assembly (BHA) coupled thereto. The system includes: a processor; sensors coupled to the top portion of the drill string and to the processor. The sensors configured to measure values of variables of the top portion of the drill string, to obtain top portion measured value. A non-transitory tangible computer readable medium having instructions recorded thereon are carried out by the processor to obtain a soft sensor to generate estimated values of variables of the BHA in accordance with the top portion measured values and in accordance with angular motion equations of the drill string. A drill string controller is configured to generate a control signal in accordance with the estimated values of variables of the BHA to control the top portion in accordance with the control signal.
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公开(公告)号:US20210236418A1
公开(公告)日:2021-08-05
申请号:US17232393
申请日:2021-04-16
Applicant: Provectus Pharmatech, Inc, , UTI Limited Partnership
Inventor: Aru Narendran , Dominic Rodrigues , Bruce Horowitz , Edward V. Pershing , Eric A. Wachter
IPC: A61K9/00 , A61K45/06 , A61P35/02 , A61K31/352
Abstract: A method of treating a mammalian subject having hematologic, non-tumorous cancer cells is disclosed. The method comprises the steps of: (A) administering to such a mammalian subject a therapeutically effective amount of a halogenated xanthene, a pharmaceutically acceptable salt or a C1-C4 alkyl ester thereof as a first cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable aqueous medium. The mammalian subject is maintained for a period of time sufficient to induce death of hematologic, non-tumorous cancer cells. A contemplated administration is typically repeated. A contemplated treatment method can also be carried out in conjunction with administration to said mammalian subject of a second therapeutically effective amount of a second, differently-acting cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable medium. The second cancer cytotoxic agent can be a small molecule or an intact antibody or paratope-containing portion thereof.
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公开(公告)号:US20210231000A1
公开(公告)日:2021-07-29
申请号:US17153492
申请日:2021-01-20
Applicant: UTI LIMITED PARTNERSHIP
IPC: E21B47/024 , E21B7/04 , E21B44/02
Abstract: Systems and methods for controlling an orientation of a tool face for a drilling rig. Multiple methods are provided that use estimated tool face orientation along with measured parameters to determine inputs to the drilling rig such that, after activation, the tool face has a desired orientation.
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公开(公告)号:US20210205470A1
公开(公告)日:2021-07-08
申请号:US17128776
申请日:2020-12-21
Applicant: UTI Limited Partnership
Inventor: Pedro SANTAMARIA
Abstract: This disclosure provides therapeutic compositions and methods for treating multiple sclerosis or a multiple sclerosis-related disorder in a subject in need thereof comprising administering an effective amount of an antigen-MHC-nanoparticle complex to the subject, wherein the antigen is a multiple sclerosis-related antigen.
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公开(公告)号:US20210155627A1
公开(公告)日:2021-05-27
申请号:US17165048
申请日:2021-02-02
Applicant: Duke University , UTI Limited Partnership
Inventor: Timothy A. J. Haystead , David A. Carlson , Douglas H. Weitzel , Justin A. MacDonald , Michael P. Walsh
IPC: C07D487/04 , A61K31/5377 , A61K31/519
Abstract: The present disclosure is directed to compounds that may selectively inhibit Death Associated Protein Kinases (DAPKs) as well as PIM kinases. The compounds can be used in methods of treating various disorders, including cancers.
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