公开(公告)号：US20220145007A1

公开(公告)日：2022-05-12

申请号：US17477927

申请日：2021-09-17

Applicant: Zhengzhou University

Inventor： Minying LIU ,  Bingfeng XUE ,  Peng FU ,  Zhe CUI ,  Xiaomeng ZHANG ,  Wei ZHAO ,  Xinchang PANG ,  Qingxiang ZHAO

IPC: C08G69/30

Abstract: The disclosure relates to a synthesis method of long carbon chain semi-aromatic nylon. The synthesis method comprises the following steps: mixing a wet powdery nylon salt, an antioxidant, a catalyst, a surfactant and pellets, and carrying out a one-step solid state polymerization under dynamic mixing to obtain a powdery nylon; under dynamic mixing, enabling the pellets to promote the stirring and mixing of the material and reducing material adhesion to the wall; the one-step solid state polymerization comprises a pre-solid state polymerization and a post-solid state polymerization; in the pre-solid state polymerization, ensuring the nylon salt and the prepolymer not to be molten; in the post-solid state polymerization, gradually reducing the system pressure to vacuum, and keeping the system pressure in vacuum state for at least 1 hour; the temperature of the post-solid state polymerization is not lower than the termination temperature of the pre-solid state polymerization.

公开(公告)号：US20220144658A1

公开(公告)日：2022-05-12

申请号：US17515642

申请日：2021-11-01

Applicant: Zhengzhou University

Inventor： Xiping CHEN

IPC: C01F7/50 ,  C01F7/30

Abstract: A method for preparing aluminum fluoride and aluminum oxide by decarburization and sodium removal of an aluminum electrolysis carbon residue is disclosed. The method includes: crushing the aluminum electrolysis carbon residue into fine particles not larger than 3 mm, adding decarburization agent into the carbon residue, mixing to obtain first mixture, adding the first mixture into a high-temperature furnace, conducting I-stage heating treatment in air atmosphere to obtain crude fluoride salt A; adding sodium removal agent into the crude fluoride salt A, mixing to obtain second mixture, adding the second mixture into high-temperature furnace, and conducting
II-stage heating treatment to obtain crude fluoride salt B; adding the crude fluoride salt B into stirring tank, adding industrial pure water, dissolving a sodium salt into water, and conducting solid-liquid separation to obtain precipitate C and sodium salt solution D; drying the precipitate C to obtain aluminum fluoride and aluminum oxide.

公开(公告)号：US20210316294A1

公开(公告)日：2021-10-14

申请号：US17119315

申请日：2020-12-11

Applicant: Zhengzhou University

Inventor： Bo MENG ,  Yifan HAN

IPC: B01J37/03 ,  B01J37/04 ,  F24H4/04 ,  B01J37/10

Abstract: The present disclosure discloses a device and a method for continuously producing catalysts based on low-temperature coprecipitation. The device mainly includes: a metal salt preparation kettle, a primary reaction kettle, a secondary reaction kettle, a precipitant preparation kettle, a circulating refrigeration system, an automatic control system, a non-aqueous solvent storage tank and a water storage tank. Independent preparation kettles are provided for rapid dissolution of the raw materials, and can be used to prepare the raw materials for the next batch during the reactions that are carried out in the primary and secondary reaction kettles; the circulating refrigeration system refrigerates the primary and secondary reaction kettles, and thus during the reaction, the low-temperature precipitant makes it possible to offset the precipitation reaction heat and the heat caused by the stirring in the primary reaction kettle, and improve the refrigeration efficiency of the primary reaction kettle.

公开(公告)号：US20210285179A1

公开(公告)日：2021-09-16

申请号：US17331656

申请日：2021-05-27

Applicant: Zhengzhou University ,  SAFEKEY Engineering Technology (Zhengzhou), Ltd.

Inventor： Fuming Wang ,  Mingsheng Shi ,  Chaojie Wang ,  Chengchao Guo ,  Peng Zhao ,  Binghan Xue ,  Yangyang Xia ,  Yanjie Hao ,  Xijun Zhang ,  Xianfeng Zhao ,  Yingli Wang

IPC: E02D3/12 ,  E02B5/02

Abstract: A method for stabilizing and lifting a channel board by underwater grouting includes (A) when the channel board is damaged, removing the damaged channel board, cleaning and leveling a gravel layer under the damaged channel board, placing an undamaged channel board installed with first grouting pipes and a second grouting pipe on the gravel layer, wherein multiple geotextile bags are respectively bound to the first grouting pipes; when the channel board is subsided, installing first grouting pipes and a second grouting pipe into first grouting holes and a second grouting hole, respectively; (B) performing a first polymer grouting through the first grouting pipes, and performing a second polymer grouting through the second grouting pipe; (C) cutting off a part of the first grouting pipes the second grouting pipe which are exposed to the channel board, and leveling incisions; and (D) removing excess polymer left on the channel board.

公开(公告)号：US20190010200A1

公开(公告)日：2019-01-10

申请号：US15758853

申请日：2016-09-09

Applicant: BEIJING BIO-TARGETING THERAPEUTICS TECHNOLOGY INC. ,  Zhengzhou University

Inventor： Yaohe Wang ,  Pengju Wang ,  Lemoine Nick ,  Dongling GAO

IPC: C07K14/54 ,  C12N15/86 ,  A61K35/761 ,  A61P35/00

Abstract: The present invention discloses a modified interleukin 12 (nsIL-12) and its gene, recombinant vector and use in manufacture of a medicament for treatment of tumors. When the oncolytic adenovirus vector carrying the modified interleukin 12 gene targets tumor tissue, the modified interleukin 12 is continuously expressed at a low level and mainly distributed in the local tumor tissue, which improves the specificity to tumor cells and reduces the systemic toxicity of interleukin 12; the modified interleukin 12 shows stronger inhibitory effect on tumor growth in intraperitoneally disseminated tumors and orthotopic tumors, and has low toxicity. The modified interleukin 12 armed oncolytic viruses show excellent antitumor effects, with a significant regression of tumors and lower toxicity compared with the existing IL-12 armed virus.

公开(公告)号：US20250158115A1

公开(公告)日：2025-05-15

申请号：US18399758

申请日：2023-12-29

Applicant: ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

Inventor： Chunsen LIU ,  Chaonan GU ,  Jingjing LI ,  Miao DU

IPC: H01M10/0565 ,  H01M50/105

Abstract: A biphasic eutectogel decoupling electrolyte and a preparation method and application thereof are provided. The biphasic eutectogel decoupling electrolyte includes an acidic eutectogel electrolyte and an alkaline eutectogel electrolyte arranged in order; the acidic eutectogel electrolyte includes a dispersion medium at least including an acidic deep eutectic solvent and a first metal salt, and the alkaline eutectogel electrolyte includes a dispersion medium at least including an alkaline deep eutectic solvent and a second metal salt.

公开(公告)号：US20250146999A1

公开(公告)日：2025-05-08

申请号：US19013237

申请日：2025-01-08

Applicant: Tsinghua University ,  Zhengzhou University ,  China Construction Seventh Engineering Division Corp., LTD.

Inventor： Dakuo Feng ,  Jianmin Zhang ,  Qingshan Wang

IPC: G01N33/24 ,  G01N3/24

Abstract: A simple shear assembly includes: a base plate detachably mounted on a loading platform, and a stacked ring group opposite to the base plate; wherein the stacked ring group comprises: a plurality of stacked rings capable of sliding relative to each other; each of the stacked rings comprises a mounting frame and a holding frame provided within the mounting frame; the mounting frame comprises a support portion and a protective portion fixed to a top part of the support portion; the protective portion comprises a limiting groove and a rolling surface provided in the limiting groove; a support portion of an above adjacent stacked ring is rolled and supported on the rolling surface, in such a manner that all the stacked rings freely stagger with each other to perform interface simple shear. The protective portion can prevent the stacked rings from overturning.

公开(公告)号：US20250136622A1

公开(公告)日：2025-05-01

申请号：US18951579

申请日：2024-11-18

Applicant: Zhengzhou University

Inventor： Shuangquan ZANG ,  Xiyan DONG ,  Xiaohong MA

IPC: C07F1/08 ,  C07D401/14

Abstract: A chiral N-heterocyclic carbene ligand-protected copper cluster, having a formula of C177H166.5Cu6F36N31.5P6, abbreviated as R/S—Cu3, belonging to a monoclinic crystal system and having a chiral space group P21, R—Cu3: a=13.5254(2) Å, b=51.4781(5) Å, c=14.9912(2) Å, α=90°, β=116.3120(10), γ=90°, V=9356.4(2) Å3; S—Cu3: a=13.5669(2) Å, b=51.5432(6) Å, c=15.0017(2) Å, α=90°, β=116.211(2), γ=90°, V=9411.7(3) Å3.

公开(公告)号：US12252817B2

公开(公告)日：2025-03-18

申请号：US18260025

申请日：2022-09-08

Applicant: ZHENGZHOU UNIVERSITY

Inventor： Ming Huang ,  Jun Zhou ,  Na Zhang ,  Chuntai Liu ,  Yuhu Chen ,  Yang Wang ,  Xianzhang Shi ,  Wei Wei

IPC: D02J1/18

Abstract: Provided is an airflow disturbance type carbon fiber spreading device. The device includes an unwinding module, an unwinding tension control module, an airflow disturbance spreading module, a winding tension stabilizing module, a deviation correction module and a winding module which are sequentially arranged along a feeding direction. The spreading mechanism includes an airflow disturbance spreading module, the airflow disturbance spreading module includes two airflow disturbance spreading assemblies, each airflow disturbance spreading assembly includes a centrifugal fan, the centrifugal fan communicates with the bottom of an airflow duct, and three spreading guide shafts are arranged side by side on the top of the airflow duct. A tension adjusting assembly is provided between the airflow disturbance spreading assemblies. A seventh spreading guide shaft (13) is located at the upper port of an airflow duct I (25) and is connected to a slider module II (34).

公开(公告)号：US12195522B2

公开(公告)日：2025-01-14

申请号：US18069456

申请日：2022-12-21

Applicant: Longhu Laboratory ,  Zhengzhou University

Inventor： Gaiping Zhang ,  Aiping Wang ,  Peiyang Ding ,  Yaning Sun ,  Yumei Chen ,  Jianguo Zhao ,  Hongliang Liu ,  Haili Wang

IPC: C07K16/10 ,  G01N33/543 ,  G01N33/569

Abstract: The present invention provides a rabies virus monoclonal antibody 2F2 and universal rabies virus antibody rapid detection test paper and belongs to the technical field of biological detection. An amino acid sequence of the monoclonal antibody 2F2 is shown as SEQ ID No. 1. The monoclonal antibody 2F2 provided by the present invention specifically binds to rabies virus G proteins, and preparation of the monoclonal antibody 2F2 into test paper has the advantages of rapidity, accuracy, sensitivity, specificity and low cost.