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公开(公告)号：US4994279A
公开(公告)日：1991-02-19
申请号：US302646
申请日：1989-01-26
CPC分类号： A61K9/5078
摘要： A multi-layered granule comprises an inner, slow-releasing layer, an outer, rapid-releasing layer and an intermediate layer provided between said slow-releasing layer and said rapid-releasing layer which intermediate layer comprises a hardened oil and hydroxypropyl cellulose or methyl cellulose.
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62.发明授权
公开(公告)号：US4936203A
公开(公告)日：1990-06-26
申请号：US392222
申请日：1989-08-09
申请人： Shigeru Aoki , Torahiko Hayashi , Yuji Suzuki
发明人： Shigeru Aoki , Torahiko Hayashi , Yuji Suzuki
CPC分类号： B65G21/12 , A21C11/00 , A21C11/103 , A21C9/08 , B65G47/26 , B65G2203/042
摘要： An apparatus for shaping and arraying spheroidal bodies is provided. The apparatus comprises a means for continuously supplying a cylindrical body comprising an outer material and a filler material, a cutter assembly having cutter members circumferentially disposed to form a central opening, and an arraying device having an endless belt for transferring a tray. The cutter members slide inwardly to close the opening, and thus the part of the cylindrical body inserted in the opening is shaped into a spheroidal body. An endless belt device is disposed beneath the cutter assembly and the belt is driven intermittently and forwardly and the frame of the endless belt device is moved back and forth in a transverse direction. By moving the belt and frame of the endless belt device so that predetermined positions of its belt are in turn moved to a position directly beneath the opening of the cutter assembly, the spheroidal bodies drop on each predetermined position on a tray placed on the belt. Therefore, the spheroidal bodies are automatically arrayed on the tray.
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公开(公告)号：US4889766A
公开(公告)日：1989-12-26
申请号：US207827
申请日：1988-06-17
CPC分类号： C09D7/1291 , B29C63/0017 , B29C70/62 , C08J5/24 , Y10T428/251 , Y10T428/252 , Y10T428/256
摘要： The present invention discloses a prepreg sheet for flake lining and a lining process using the same.The prepreg sheet for flake lining according to the present invention comprises a sheet made of a matrix resin containing a curing agent and a thickening agent and flakes dispersed in the matrix resin in a state nearly parallel to the surface of the sheet.The lining process using a prepreg sheet for flake lining according to the present invention comprises the following steps:(1) a step of conditioning the surface of a substrate,(2) a step of forming a primer layer on the conditioned surface,(3) a step of bonding a prepreg sheet for flake lining comprising a sheet made of a matrix resin containing a thickening agent and a curing agent and flakes dispersed in the matrix resin in a state nearly parallel to the surface of the sheet onto the primer layer, and(4) a step of curing the matrix resin of the prepreg sheet.
摘要翻译： 本发明公开了一种用于片状衬片的预浸料片材和使用其的衬里方法。 根据本发明的片状衬片的预浸料片包括由基质树脂制成的片材，其含有固化剂和增稠剂，并且以几乎平行于片材表面的状态分散在基质树脂中。 使用本发明的片状衬片用预浸料片的衬里工艺包括以下步骤：（1）调理衬底表面的步骤，（2）在调理表面上形成底漆层的步骤，（3 ）将包含由含有增稠剂和固化剂的基质树脂制成的片材和片状树脂中分散在片状表面的片状物的片材粘合到底片层的步骤， 和（4）固化预浸渍片材的基体树脂的步骤。
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公开(公告)号：US4730076A
公开(公告)日：1988-03-08
申请号：US942146
申请日：1986-12-16
IPC分类号： C07K5/075 , C07C101/02
CPC分类号： C07K5/0613
摘要： The present invention relates to a process for producing .alpha.-aspartyl-phenylalanine ester represented by the general formula ##STR1## wherein R' represents an alkyl group having 1 to 4 carbon atoms, by reducing an N-protected-N-hydroxymethyl-.alpha.-aspartyl-phenylalanine ester represented by the general formula ##STR2## wherein R represents an organic mioety which can be substituted reductively by hydrogen, and R' is as defined above, with hydrogen gas or formic acid, in the presence of a reduction catalyst and an aromatic primary amine. According to the present invention, there can be obtained a high purity .alpha.-aspartyl-phenylalanine ester with a high yield.
摘要翻译： 本发明涉及通过还原N-保护的N-羟甲基-α-谷氨酰胺来制备由通式“IMAGE”表示的α-天门冬酰胺 - 苯丙氨酸酯的方法，其中R'代表具有1至4个碳原子的烷基， 由通式
表示的天冬氨酰基 - 苯丙氨酸酯，其中R表示可在氢还原催化剂和还原催化剂存在下用氢气或甲酸还原的氢被还原反应的R'和R'定义的有机二氧化物， 芳族伯胺。 根据本发明，可以高产率地得到高纯度的α-天冬氨酰基苯丙氨酸酯。 -
公开(公告)号：US4667054A
公开(公告)日：1987-05-19
申请号：US824089
申请日：1986-01-30
IPC分类号： C07B57/00 , C07B31/00 , C07C67/00 , C07C227/00 , C07C227/18 , C07C227/34 , C07C229/08
CPC分类号： C07C227/34
摘要： This invention relates to a process for producing optically active valine, characterized by optically resolving DL-valine hydrochloride in a solvent containing an amine salt, a sulfonic acid or a carboxylic acid and isolating optically active valine after the decomposition of the obtained optically active valine hydrochloride.
摘要翻译： 本发明涉及一种光学活性缬氨酸的制备方法，其特征在于将光学活性缬氨酸盐酸盐分解后，在含有胺盐，磺酸或羧酸的溶剂中光学拆分DL-缬氨酸盐酸盐，并分离光学活性缬氨酸 。
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公开(公告)号：US4198524A
公开(公告)日：1980-04-15
申请号：US886745
申请日：1978-03-15
IPC分类号： C07B57/00 , C07B31/00 , C07C59/50 , C07C67/00 , C07C227/00 , C07C227/18 , C07C227/34 , C07C229/08 , C07C313/00 , C07C323/58 , C07C65/135
CPC分类号： C07C59/50
摘要： Two optically active amino acid-mandelic acid complexes are obtained by reacting in a solvent under pH conditions of 1.0-4.0, an amino acid expressed by a general formula ##STR1## (in which R represents a methyl group, an ethyl group or a methylthioethyl group) and mandelic acid, one of the acids being an optically active substance and the other being a racemic modification, and optically resolving the resulting complexes into two diastereomers by using a solubility difference therebetween. The optically active complexes are each decomposed by means of an acid, a strongly acidic ion-exchange resin, or a weakly basic ion-exchange resin to obtain optically active amino acids or optically active mandelic acid.
摘要翻译： 两种光学活性的氨基酸 - 扁桃酸配合物通过在溶剂中在1.0-4.0的pH条件下反应得到，该通式为通式（IMAGE）表示的氨基酸（其中R表示甲基，乙基或甲基硫代乙基 基团）和扁桃酸，其中一种酸是光学活性物质，另一种是外消旋体改性，并通过使用它们之间的溶解度差异将所得复合物光学拆分成两种非对映异构体。 光学活性复合物各自通过酸，强酸性离子交换树脂或弱碱性离子交换树脂分解，得到光学活性氨基酸或光学活性扁桃酸。
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公开(公告)号：US3981636A
公开(公告)日：1976-09-21
申请号：US628403
申请日：1975-11-03
申请人： Shigeru Aoki , Katuya Suzuki , Tosimitu Sakai
发明人： Shigeru Aoki , Katuya Suzuki , Tosimitu Sakai
CPC分类号： F04B45/04 , F04B39/108 , F04B9/06 , Y10T137/784 , Y10T137/786
摘要： To suck and discharge the air into and from a pressure reducing chamber of a vacuum pump, a check valve comprises a valve body made of plastic material in a mushroom configuration, and a plate member which includes a flat valve seat surface to be engaged with the annular rim of the cap portion of the valve body, an assembling hole to be coupled with the neck portion of the valve body, and a plurality of openings positioned symmetrically on a circle concentric with the assembling hole to normally be closed by the cap portion of the valve body. The neck portion of the valve body is assembled with the assembling hole under axially and radially compressed condition to air-tightly engage the annular rim of the cap portion of the valve body on the valve seat surface.
摘要翻译： 为了将空气吸入和排出真空泵的减压室，止回阀包括由蘑菇构造的塑料材料制成的阀体，以及板构件，其包括与阀座表面接合的扁平阀座表面 阀体的盖部分的环形边缘，与阀体的颈部部分联接的组装孔和多个开口，其对称地位于与组装孔同心的圆上，以通常由帽部分封闭 阀体。 阀体的颈部与轴承和径向压缩状态下的组装孔组装在一起，以气密地接合在阀座表面上的阀体盖部分的环形边缘。
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