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公开(公告)号：US07927835B2
公开(公告)日：2011-04-19
申请号：US12167680
申请日：2008-07-03
Applicant: Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
Inventor： Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/4703 , C07K14/51 , C07K14/52 , C07K14/5431 , C07K14/705 , C07K16/2851 , C07K16/2854 , C07K19/00 , C07K2319/00 , C07K2319/24 , C12N9/10 , C12N9/1051 , C12N9/6454 , C12N2770/36222
Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
Abstract translation: 公开了一种新型P-选择素配体糖蛋白，其包含SEQ ID NO：2所示的氨基酸序列或SEQ ID NO：4所示的氨基酸序列。 还公开了编码P-选择素配体蛋白的DNA序列，以及载体，宿主细胞和制备P-选择蛋白配体蛋白的方法。 还公开了含有P-选择素配体蛋白质的药物组合物和治疗由P-选择蛋白和E-选择素介导的细胞间粘附特征的炎性疾病状态的方法。
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62.发明授权System and method for determining differences between software configurations 有权用于确定软件配置之间的差异的系统和方法公开(公告)号：US07926049B1
公开(公告)日：2011-04-12
申请号：US11388174
申请日：2006-03-23
Applicant: Ravindra Kumar
Inventor： Ravindra Kumar
IPC: G06F9/45
CPC classification number: G06F9/44505
Abstract: A system and method for determining differences between configurations of a software program. A configuration differencing command generates a hash table of configuration keys and values for each of the configurations being compared. A key is selected from a first hash table and the command determines if an identical key exists in the second hash table. If the key exists in the second hash table, a comparison is made of the values associated with the keys and, if the values are not identical, the configuration differencing command displays the differences to an administrator.
Abstract translation: 一种用于确定软件程序的配置之间的差异的系统和方法。 配置差异命令为每个正在比较的配置生成配置密钥和值的哈希表。 从第一散列表中选择密钥，并且该命令确定在第二哈希表中是否存在相同的密钥。 如果密钥存在于第二个哈希表中，则对与密钥相关的值进行比较，如果值不相同，则配置差异命令将显示与管理员的差异。
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63.发明申请METHODS, SYSTEMS AND/OR APPARATUS RELATING TO FREQUENCY-TUNED TURBINE BLADES 审中-公开与频率调节涡轮叶片相关的方法，系统和/或装置公开(公告)号：US20100166550A1
公开(公告)日：2010-07-01
申请号：US12347329
申请日：2008-12-31
Applicant: Siddaraja M. Devangada , Ravindra Kumar
Inventor： Siddaraja M. Devangada , Ravindra Kumar
CPC classification number: F01D5/16 , F01D5/26 , F01D9/041 , Y10T29/49336
Abstract: A method of tuning a compressor stator blade, having a base portion and an airfoil portion, to achieve a desired natural frequency, comprising: a) identifying the natural frequency of the compressor stator blade; b) determining a different target natural frequency for the compressor stator blade; and c) removing material from at least one of the side surfaces of the base portion of the compressor stator blade in an amount and in a configuration that achieves the target natural frequency.
Abstract translation: 一种调节压缩机定子叶片的方法，所述压缩机定子叶片具有基部和翼型部分，以实现期望的固有频率，包括：a）识别压缩机定子叶片的固有频率; b）确定压缩机定子叶片的不同目标固有频率; 以及c）以达到目标固有频率的量和配置从所述压缩机定子叶片的基部的至少一个侧表面去除材料。
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公开(公告)号：US07563760B2
公开(公告)日：2009-07-21
申请号：US09935144
申请日：2001-08-21
Applicant: Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
Inventor： Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
IPC: A61K38/00 , A61K39/395
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/4703 , C07K14/51 , C07K14/52 , C07K14/5431 , C07K14/705 , C07K16/2851 , C07K16/2854 , C07K19/00 , C07K2319/00 , C07K2319/24 , C12N9/10 , C12N9/1051 , C12N9/6454 , C12N2770/36222
Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
Abstract translation: 公开了一种新型P-选择素配体糖蛋白，其包含SEQ ID NO：2所示的氨基酸序列或SEQ ID NO：4所示的氨基酸序列。 还公开了编码P-选择素配体蛋白的DNA序列，以及载体，宿主细胞和制备P-选择蛋白配体蛋白的方法。 还公开了含有P-选择素配体蛋白质的药物组合物和治疗由P-选择蛋白和E-选择素介导的细胞间粘附特征的炎性疾病状态的方法。
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公开(公告)号：US20090104180A1
公开(公告)日：2009-04-23
申请号：US12167663
申请日：2008-07-03
Applicant: Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
Inventor： Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
IPC: A61K39/395 , A01N1/02 , A61K38/16 , A61K38/43 , A61K38/10
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/4703 , C07K14/51 , C07K14/52 , C07K14/5431 , C07K14/705 , C07K16/2851 , C07K16/2854 , C07K19/00 , C07K2319/00 , C07K2319/24 , C12N9/10 , C12N9/1051 , C12N9/6454 , C12N2770/36222
Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
Abstract translation: 公开了一种新型P-选择素配体糖蛋白，其包含SEQ ID NO：2所示的氨基酸序列或SEQ ID NO：4所示的氨基酸序列。 还公开了编码P-选择素配体蛋白的DNA序列，以及载体，宿主细胞和制备P-选择蛋白配体蛋白的方法。 还公开了含有P-选择素配体蛋白质的药物组合物和治疗由P-选择蛋白和E-选择素介导的细胞间粘附特征的炎性疾病状态的方法。
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Patent Agency Ranking
公开(公告)号：US20090028883A1
公开(公告)日：2009-01-29
申请号：US12167705
申请日：2008-07-03
Applicant: Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
Inventor： Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
IPC: A61K39/395 , C07K14/47 , A61K38/17 , A61P29/00 , C07K16/18
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/4703 , C07K14/51 , C07K14/52 , C07K14/5431 , C07K14/705 , C07K16/2851 , C07K16/2854 , C07K19/00 , C07K2319/00 , C07K2319/24 , C12N9/10 , C12N9/1051 , C12N9/6454 , C12N2770/36222
Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
Abstract translation: 公开了一种新型P-选择素配体糖蛋白，其包含SEQ ID NO：2所示的氨基酸序列或SEQ ID NO：4所示的氨基酸序列。 还公开了编码P-选择素配体蛋白的DNA序列，以及载体，宿主细胞和制备P-选择蛋白配体蛋白的方法。 还公开了含有P-选择素配体蛋白质的药物组合物和治疗由P-选择蛋白和E-选择素介导的细胞间粘附特征的炎性疾病状态的方法。
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公开(公告)号：US20080280327A1
公开(公告)日：2008-11-13
申请号：US12167680
申请日：2008-07-03
Applicant: Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
Inventor： Glenn R. Larsen , Dianne S. Sako , Xiao-Jia Chang , Geertruida M. Veldman , Dale Cumming , Ravindra Kumar , Gray Shaw
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/4703 , C07K14/51 , C07K14/52 , C07K14/5431 , C07K14/705 , C07K16/2851 , C07K16/2854 , C07K19/00 , C07K2319/00 , C07K2319/24 , C12N9/10 , C12N9/1051 , C12N9/6454 , C12N2770/36222
Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
Abstract translation: 公开了一种新型P-选择素配体糖蛋白，其包含SEQ ID NO：2所示的氨基酸序列或SEQ ID NO：4所示的氨基酸序列。 还公开了编码P-选择素配体蛋白的DNA序列，以及载体，宿主细胞和制备P-选择蛋白配体蛋白的方法。 还公开了含有P-选择素配体蛋白质的药物组合物和治疗由P-选择蛋白和E-选择素介导的细胞间粘附特征的炎性疾病状态的方法。
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68.发明申请Platelet glycoprotein Ib alpha variant fusion polypeptides and methods of use thereof 失效血小板糖蛋白Ibα变体融合多肽及其使用方法公开(公告)号：US20050089888A1
公开(公告)日：2005-04-28
申请号：US10868371
申请日：2004-06-14
Applicant: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
Inventor： Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
IPC: A61K38/00 , A61K38/36 , C07K14/705 , C07K14/745 , C12N15/12 , C12Q1/68 , C07H21/04 , C12N9/22
CPC classification number: C07K14/705 , A61K38/00 , C07K2319/00
Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
Abstract translation: 本发明提供了用于治疗或预防血管相关疾病的组合物和方法。
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公开(公告)号：US5869307A
公开(公告)日：1999-02-09
申请号：US984246
申请日：1997-12-03
Applicant: Francis Sullivan , Ronald Kriz , Ravindra Kumar
Inventor： Francis Sullivan , Ronald Kriz , Ravindra Kumar
CPC classification number: C12N9/88
Abstract: The invention provides a novel GDP-mannose 4,6-dehydratase.
Abstract translation: 本发明提供了一种新的GDP-甘露糖4,6-脱水酶。
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公开(公告)号：US5728568A
公开(公告)日：1998-03-17
申请号：US753233
申请日：1996-11-22
Applicant: Francis Sullivan , Ronald Kriz , Ravindra Kumar
Inventor： Francis Sullivan , Ronald Kriz , Ravindra Kumar
CPC classification number: C12N9/88
Abstract: The invention provides a novel GDP-mannose 4,6-dehydratase.
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