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61.发明授权Motion synchronized destruction for three-dimensional reperfusion mapping in medical diagnostic ultrasound imaging 有权运动同步破坏用于医学诊断超声成像中的三维再灌注映射公开(公告)号：US09066674B2
公开(公告)日：2015-06-30
申请号：US12726260
申请日：2010-03-17
申请人： Ismayil M. Guracar
发明人： Ismayil M. Guracar
摘要： Destruction for reperfusion in medical diagnostic ultrasound is synchronized to motion. Perfusion data for a volume is acquired sequentially for different segments of the volume. For a given segment, such as a planar region, motion tracking within the segment is performed. If sufficient registration or correlation exists at the completion of a sequence of scans for the current segment, then a lesser amount of movement is occurring. At this point, the transmission of contrast agent destructive acoustic energy is performed in the next segment. Tracking is repeated for the next segment to synchronize the switch to yet another segment. Other regions for tracking can be used. By controlling transmission of destruction pulses, more reliable perfusion quantities in a volume may be determined.
摘要翻译： 医学诊断超声的再灌注破坏与运动同步。 针对卷的不同段顺序获取体积的灌注数据。 对于给定的段，例如平面区域，执行段内的运动跟踪。 如果在当前段的扫描序列完成时存在足够的注册或相关性，则发生较少量的移动。 此时，在下一段中执行造影剂破坏性声能的传输。 对下一个段重复跟踪，以将交换机同步到另一个段。 可以使用其他跟踪区域。 通过控制破坏脉冲的传输，可以确定体积中更可靠的灌注量。
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62.发明申请Motion Artifact Suppression for Three-Dimensional Parametric Ultrasound Imaging 审中-公开运动神经抑制三维参数超声成像公开(公告)号：US20150031995A1
公开(公告)日：2015-01-29
申请号：US13952475
申请日：2013-07-26
申请人： Ismayil M. Guracar
发明人： Ismayil M. Guracar
CPC分类号： A61B8/5276 , A61B8/06 , A61B8/0891 , A61B8/145 , A61B8/483 , A61B8/5207 , G01S7/52095
摘要： Motion artifacts are suppressed for three-dimensional parametric ultrasound imaging. Motion tracking is performed so that the parameter values derived over time are based on return from the same locations. Distortion due to the scan pattern is accounted for in the results of the motion tracking, such as by re-sampling the results to deal with discontinuity in time between data from adjacent sub-volumes and/or by aligning the scan pattern based on a direction of motion.
摘要翻译： 运动伪影被抑制用于三维参数超声成像。 执行运动跟踪，使得随时间推导的参数值基于从相同位置的返回。 在运动跟踪的结果中考虑到扫描模式的失真，例如通过重新采样结果来处理来自相邻子体积的数据之间的时间上的不连续性和/或通过基于方向对齐扫描图案 的运动。
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公开(公告)号：US08177719B2
公开(公告)日：2012-05-15
申请号：US11152521
申请日：2005-06-14
IPC分类号： A61B8/14
摘要： Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence. Using cubic fundamental sensitive techniques with other motion estimation techniques, such as two-dimensional velocity estimation or speckle tracking, may operate better than using other contrast agent detection techniques because of substantially reduced clutter.
摘要翻译： 可以通过处理立方基本信息来获得容器中诸如冠状动脉之间的流动的高度特异性测量。 通过显示具有高度对比组织特异性的血管中的流动，基于超声的基于3D造影剂的冠状动脉血管造影可能是可能的。 与三次基本能量的显示同时提供来自三次基本信号的试剂速度的测量和显示，例如提供由能量和速度两者分度的显示图。 结合长速度测量间隔的三次基波检测的高脉冲重复频率（PRF）可以提高低速度灵敏度和测量精度。 脉冲波（PW）多普勒可以通过使用立方基本敏感脉冲序列来改善。 使用三维基本敏感技术与其他运动估计技术（如二维速度估计或斑点跟踪）相比，使用其他造影剂检测技术的操作可能比实际上减少的杂波更好。
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64.发明申请公开(公告)号：US20090187103A1
公开(公告)日：2009-07-23
申请号：US12011099
申请日：2008-01-23
申请人： Ismayil M. Guracar
发明人： Ismayil M. Guracar
CPC分类号： A61B8/481 , A61B8/06 , A61B8/13 , G01S15/108
摘要： The effectiveness of contrast agent destruction is determined. Locations of ineffectively destroyed contrast agents are identified. The response from undestroyed contrast agents may be distinguished from response from tissue due to saturation or from rapid perfusion. The locations may be highlighted on resulting images, indicating to the user locations not associated with perfusion. The user may make a diagnosis on perfusion rather than a lack of destruction of contrast agents.
摘要翻译： 确定造影剂破坏的有效性。 识别出无效破坏的造影剂的位置。 来自未破坏的造影剂的反应可以区别于由于饱和或来自快速灌注的组织的反应。 可以在所得图像上突出显示位置，指示用户与灌注不相关的位置。 用户可以对灌注进行诊断，而不是造成造影剂的破坏。
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公开(公告)号：US20090082671A1
公开(公告)日：2009-03-26
申请号：US12233940
申请日：2008-09-19
IPC分类号： A61B8/14
摘要： Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence. Using cubic fundamental sensitive techniques with other motion estimation techniques, such as two-dimensional velocity estimation or speckle tracking, may operate better than using other contrast agent detection techniques because of substantially reduced clutter.
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公开(公告)号：US06899681B1
公开(公告)日：2005-05-31
申请号：US10077499
申请日：2002-02-15
CPC分类号： G01S7/52096 , G01S7/52026 , G03B42/06
摘要： Automated determination and setting of an ultrasound system transmit power level is provided for contrast agent imaging. Low mechanical index imaging of contrast agents allows substantially continuous imaging of contrast agents without destruction. By comparing data associated with different transmit power levels, different delays between acquisition or different acquisition sequences, a contrast agent imaging transmit power generally minimizing destruction of contrast agents and maximizing signal-to-noise ratio is automatically determined.
摘要翻译： 提供超声系统发射功率水平的自动确定和设置用于造影剂成像。 造影剂的低机械指数成像允许对比剂的基本连续成像而不破坏。 通过比较与不同发射功率电平相关联的数据，可以自动确定采集或不同采集序列之间的不同延迟，通常最小化对比剂的破坏和最大化信噪比的造影剂成像发射功率。
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67.发明授权公开(公告)号：US06858010B2
公开(公告)日：2005-02-22
申请号：US10430846
申请日：2003-05-06
申请人： Ismayil M. Guracar , Wayne J. Gueck
发明人： Ismayil M. Guracar , Wayne J. Gueck
CPC分类号： G01S7/52085 , G01S15/8911 , G01S15/8995
摘要： Methods and systems are provided for identifying clinical markers in spatial compounded imaging. For example, an image responsive to less spatial compounding more likely preserves clinical markers than a steered compound image. By displaying both images, clinical markers are identified by the user from one image and other diagnostic information is obtained from the steered compound image. As another example, clinical marker information is identified and added back into or highlighted on a spatial compound image for identification by the user.
摘要翻译： 提供了用于识别空间复合成像中临床标志物的方法和系统。 例如，响应于较少空间复合的图像比转向复合图像更可能保留临床标记。 通过显示两个图像，临床标记由用户从一个图像识别，并且其他诊断信息从转向复合图像获得。 作为另一个示例，临床标记信息被识别并添加到空间复合图像中或突出显示在用于用户识别的空间复合图像上。
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公开(公告)号：US06629926B1
公开(公告)日：2003-10-07
申请号：US09354254
申请日：1999-07-15
IPC分类号： A61B800
CPC分类号： G01S7/52023 , A61B8/00 , G01S7/52034 , G01S7/5206
摘要： An apparatus and method for processing ultrasound data is provided. The apparatus includes an interface operatively connected to a memory, a programmable single instruction multiple data processor (or two symmetric processors), a source of acoustic data (such as a data bus) and a system bus. The memory stores data from the processor, ultrasound data from the source, and data from the system bus. The processor has direct access to the memory. Alternatively, the system bus has direct access to the memory. The interface device translates logically addressed ultrasound data to physically addressed ultrasound data for storage in a memory. The translation is the same for data from both the processor and the source for at least a portion of a range of addresses. The memory stores both ultrasound data and various of: beamformer control data, instruction data for the processor, display text plane information, control plane data, and a table of memory addresses. One peripheral connects to the ultrasound apparatus. An interface adapter, powered from the ultrasound apparatus, translates information transferred between the peripheral and the ultrasound apparatus. The adapter connects non-standard peripherals to various standard interfaces on the ultrasound apparatus.
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公开(公告)号：US06544184B1
公开(公告)日：2003-04-08
申请号：US09942009
申请日：2001-08-28
申请人： Ismayil M. Guracar
发明人： Ismayil M. Guracar
IPC分类号： A61B814
CPC分类号： A61B8/481 , G01S7/52038 , G01S7/52041 , G01S7/52046 , G01S7/52085 , G01S15/8979
摘要： Line synthesis avoids artifacts from differences in collateral destruction of contrast agent. Data representing a plurality of scan lines is received in response to each transmit event. Transmission and reception along the same scan lines are repeated a plurality of times for loss correlation imaging. Coherent data or data prior to detection along two or more scan lines is combined, removing differences. The combined data represents a synthesized line of data for detection. Line data representing contrast agents or not representing contrast agents may be synthesized from detected data. Detected data or data in the magnitude and phase domain representing two or more scan lines is combined. By altering the data provided to a flow processor or Doppler data detector, the relative phase of the data representing the two scan lines is determined. A magnitude for a synthetic line is calculated as a function of the magnitude of data representing two separate scan lines and the relative phase.
摘要翻译： 线合成避免造影剂的附带破坏差异造成的伪影。 响应于每个发送事件接收表示多条扫描线的数据。 对相同的扫描线的发送和接收被多次重复用于丢失相关成像。 在沿着两条或更多条扫描线的检测之前的相干数据或数据被组合，消除差异。 组合数据表示用于检测的合成数据线。 可以从检测到的数据合成表示造影剂的代表或不代表造影剂的线数据。 检测到的数据或表示两条或更多条扫描线的幅度和相位域中的数据被组合。 通过改变提供给流程处理器或多普勒数据检测器的数据，确定表示两条扫描线的数据的相对相位。 根据表示两条分离的扫描线和相对相位的数据的幅度来计算合成线的幅度。
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公开(公告)号：US06241677B1
公开(公告)日：2001-06-05
申请号：US09478662
申请日：2000-01-06
申请人： Ismayil M. Guracar , Samuel H. Maslak , John W. Allison , Paul E. Chandler , John I. Jackson , Arvind Jain , Laurence S. McCabe
发明人： Ismayil M. Guracar , Samuel H. Maslak , John W. Allison , Paul E. Chandler , John I. Jackson , Arvind Jain , Laurence S. McCabe
IPC分类号： A61B800
CPC分类号： G01S15/8988 , A61B8/08 , G01S7/52023 , G01S7/52025 , G01S7/52034 , G01S7/52038 , G01S7/52063 , G01S7/52071 , G01S15/895 , G01S15/8979
摘要： A method and apparatus for quantifying and displaying ultrasound signals in an ultrasonic system are provided. A first signal value for each of at least one spatial location in a region of interest is acquired at a first time, and the signal values are summed to obtain a first surface integral value. A second signal value for each of said at least one spatial location in said region of interest is acquired at a second time, and the second signal values are summed to obtain a second surface integral value. The first surface integral value is summed with the second surface integral value to obtain a time based integral. The time based integral is displayed. Other quantities based on any of various ultrasound parameters, such as Doppler energy, Doppler velocity and B-mode intensity, are calculated and displayed as quantities or as waveforms as a function of time. Furthermore, various comparisons of quantities and waveforms are provided. Image plane data or other ultrasound data are used in the calculations. Finally, a histogram data structure is provided to aid calculation of the various quantities.
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