公开(公告)号：US20100014726A1

公开(公告)日：2010-01-21

申请号：US12302897

申请日：2007-05-21

申请人： Dirk Schaefer ,  Andreas Engler ,  Babak Movassaghi ,  Volker Rasche ,  Michael Grass

发明人： Dirk Schaefer ,  Andreas Engler ,  Babak Movassaghi ,  Volker Rasche ,  Michael Grass

IPC分类号： G06K9/00 ,  G06K9/36

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/481 ,  A61B6/5288 ,  A61B6/541 ,  G06T3/0037 ,  G06T7/20 ,  G06T2207/10081 ,  G06T2207/20016 ,  G06T2207/30101

摘要： In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

摘要翻译： 在估计小血管运动时可能出现三维旋转X射线冠状动脉成像问题。 根据本发明的示例性实施例，提供了一种检查装置，其适用于通过用于每个心脏相的全局仿射变换执行分层运动估计，随后是血管分支选择仿射和非仿射变换。 这可以提供改进的图像质量。

公开(公告)号：US07574026B2

公开(公告)日：2009-08-11

申请号：US10545184

申请日：2004-01-23

申请人： Volker Rasche ,  Babak Movassaghi

发明人： Volker Rasche ,  Babak Movassaghi

IPC分类号： G06K9/00

CPC分类号： G06T11/008 ,  G06T17/10 ,  G06T2211/404 ,  G06T2211/412

摘要： The invention provides a method for 3D modeling of a three-dimensional tubular structure of an examination object from 2D projection images (D) of the structure taken from different projection directions. The method has the following steps: reconstruction of a 3D image from the 2D projection images (D); selection of at least one 3D central line point (MO) in the 3D image, said 3D central line point being located in the structure; segmentation of 3D central line points (M) of the structure in the 3D image; forward projection of the 3D central line points (M), which have been segmented in the 3D image, into 2D projection images (D′); determination of border points of the structure in the 2D projection images (D′) on the basis of 3D central line points (Z) that have been projected in; and back-projection of the border points from the 2D projection image (D′) into the 3D image.

摘要翻译： 本发明提供一种用于从取自不同投影方向的结构的2D投影图像（D）对检查对象的三维管状结构进行3D建模的方法。 该方法具有以下步骤：从2D投影图像（D）重建3D图像; 选择所述3D图像中的至少一个3D中心线点（MO），所述3D中心线点位于所述结构中; 分割3D图像中三维中心线（M）的结构; 已经在3D图像中分割的3D中心线点（M）的向前投影成2D投影图像（D'）; 根据已经投影的3D中心线点（Z）确定2D投影图像（D'）中的结构的边界点; 并将边界点从2D投影图像（D'）反投影到3D图像中。

公开(公告)号：US07539529B2

公开(公告)日：2009-05-26

申请号：US10553770

申请日：2004-04-21

申请人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

发明人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

IPC分类号： A61B6/00 ,  A61B6/02

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/504

摘要： The invention relates to an X-ray imaging device for visualizing the blood flow in a coronary vascular tree of a patient. According to the invention a first set (1) of X-ray projection images of the vascular tree is recorded during various phases of the heart cycle with simultaneous recording of the ECG (2) of the patient. By means of a suitable program control, computer means (17) of the device according to the invention a reconstruction then follows of the three-dimensional structure of the vascular tree during the various phases of the heart cycle. The invention proposes, to determine the time-dependent concentration of contrast agent within the reconstructed three-dimensional structure of the vascular tree, that local image areas within the X-ray projection images of the second set (6) assigned to individual vascular segments (5, 8) are located in accordance with the spatial positions of the vascular segments (5, 8) in the relevant phase of the heart cycle. The concentration of contrast agent in the area of the vascular segments (5, 8) is then determined by evaluation of the X-ray absorption within the local image areas found.

摘要翻译： 本发明涉及用于使患者的冠状动脉血管树中的血流可视化的X射线成像装置。 根据本发明，在心脏周期的各个阶段记录血管树的X射线投影图像的第一组（1），同时记录患者的ECG（2）。 通过合适的程序控制，根据本发明的装置的计算机装置（17）在心脏周期的各个阶段期间重建血管树的三维结构。 本发明提出，为了确定造影剂在血管树的重建三维结构内的时间依赖性浓度，将第二组（6）的X射线投影图像内的局部图像区域分配给各个血管节段 5,8）根据心脏周期的相关阶段中血管段（5,8）的空间位置来定位。 然后通过评估所发现的局部图像区域内的X射线吸收来确定血管片段（5,8）区域中造影剂的浓度。

公开(公告)号：US07505551B2

公开(公告)日：2009-03-17

申请号：US10568838

申请日：2004-08-10

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： A61B6/03

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/466 ,  A61B6/504 ,  A61B6/541

摘要： The invention relates to a method and a device for the three-dimensional reconstruction of the flow conditions in a vascular system (3), in which, in a first phase after the beginning of a contrast-medium injection, X-ray projection pictures are produced from the same direction (A) at a high picture-taking rate in order to observe the inflow of the contrast medium. When the contrast medium fills the vascular system (3), a rotation of the Xray device (1) takes place during which projection pictures are produced at a lower picture taking rate and/or at a lower radiation dose, from which pictures the three-dimensional structure of the vascular tree can be reconstructed. Optionally, at the end of the rotation, projection pictures may again be taken from a fixed direction that observe the drainage of the contrast medium from the vascular system (3).

摘要翻译： 本发明涉及一种用于三维重建血管系统（3）中的流动状态的方法和装置，其中在开始造影剂注射后的第一阶段，X射线投影图像是 以相同的方向（A）以高拍摄速度产生，以观察造影剂的流入。 当造影剂填充血管系统（3）时，发生X射线装置（1）的旋转，在该旋转装置（1）期间以较低的拍摄速度和/或较低的辐射剂量产生投影图像， 可以重建血管树的三维结构。 可选地，在旋转结束时，投影图片可以再次从观察造影剂从血管系统（3）排出的固定方向获取。

公开(公告)号：US20080221435A1

公开(公告)日：2008-09-11

申请号：US11997421

申请日：2006-07-12

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： A61B5/05

CPC分类号： A61B5/06 ,  A61B34/20 ,  A61B90/10 ,  A61B90/37 ,  A61B2034/105 ,  A61B2034/2051 ,  A61B2034/2068 ,  A61B2090/376 ,  A61B2090/3954 ,  A61B2090/3983

摘要： A method and system for navigation of a medical instrument, including: introducing at least three reference device(s) disposed to at least three reference locations; employing an imaging and guidance system to acquire a plurality of image projections corresponding to a desired anatomy including the reference devices, the plurality of image projections being sufficient to permit generating a three-dimensional modeling or reconstruction images corresponding to the reference devices. The method also includes measuring a position of the reference devices; formulating a transformation matrix based on comparing positions of the reference devices computed from the modeling or reconstruction images with the measured positions of the reference devices; and superimposing an image of a medical instrument in at least one of the plurality of image projections based on the transformation matrix and a position of the medical instrument.

摘要翻译： 一种用于医疗器械导航的方法和系统，包括：引入设置在至少三个参考位置的至少三个参考装置; 使用成像和引导系统来获取对应于包括参考装置的期望解剖结构的多个图像投影，所述多个图像投影足以允许生成对应于参考装置的三维建模或重建图像。 该方法还包括测量参考装置的位置; 基于将从建模或重建图像计算的参考装置的位置与参考装置的测量位置的比较位置来制定变换矩阵; 以及基于所述变换矩阵和所述医疗器械的位置，将所述医疗器械的图像叠加在所述多个图像投影中的至少一个中。

公开(公告)号：US20080095303A1

公开(公告)日：2008-04-24

申请号：US11573577

申请日：2005-08-17

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： A61B6/03

CPC分类号： A61B6/481 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/466 ,  A61B6/482 ,  A61B6/504

摘要： The invention relates to a method and an examination apparatus for the evaluation of X-ray projections (31-33, 41-43) that were generated with a rotational X-ray device (10) from different directions and with an energy level varying periodically from projection to projection. Said variation may for example be achieved by a continuously modulated tube voltage (V). Two different 3D-images (35, 45) may be reconstructed from the X-ray projections (31-33, 41-43) which belong to the different energy levels, and said 3D-images may then be compared voxel by voxel in order to segment structures (50) of interest due to contrast differences.

摘要翻译： 本发明涉及一种用于评估由旋转X射线装置（10）从不同方向产生并具有周期性变化的能量水平的X射线投影（31-33,41-43）的方法和检查装置 从投影到投影。 所述变化例如可以通过连续调制的管电压（V）来实现。 可以从属于不同能量级的X射线投影（31-33,41-43）重构两个不同的3D图像（35,45），然后可以按照体素的顺序将所述3D图像与体素进行比较 以由于对比度差异来分割感兴趣的结构（50）。

公开(公告)号：US20060210134A1

公开(公告)日：2006-09-21

申请号：US10568838

申请日：2004-08-10

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： G06K9/00

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/466 ,  A61B6/504 ,  A61B6/541

摘要： The invention relates to a method and a device for the three-dimensional reconstruction of the flow conditions in a vascular system (3), in which, in a first phase after the beginning of a contrast-medium injection, X-ray projection pictures are produced from the same direction (A) at a high picture-taking rate in order to observe the inflow of the contrast medium. When the contrast medium fills the vascular system (3), a rotation of the Xray device (1) takes place during which projection pictures are produced at a lower picturetaking rate and/or at a lower radiation dose, from which pictures the three-dimensional structure of the vascular tree can be reconstructed. Optionally, at the end of the rotation, projection pictures may again be taken from a fixed direction that observe the drainage of the contrast medium from the vascular system (3).

摘要翻译： 本发明涉及一种用于三维重建血管系统（3）中的流动状态的方法和装置，其中在开始造影剂注射后的第一阶段，X射线投影图像是 以相同的方向（A）以高拍摄速度产生，以观察造影剂的流入。 当造影剂填充血管系统（3）时，发生X射线装置（1）的旋转，在此期间以较低的拍摄速度和/或较低的辐射剂量产生投影图像，从该图像的三维 可以重建血管树的结构。 可选地，在旋转结束时，投影图片可以再次从观察造影剂从血管系统（3）排出的固定方向获取。

公开(公告)号：US20060142984A1

公开(公告)日：2006-06-29

申请号：US10543394

申请日：2004-01-23

申请人： Jurgen Weese ,  Volker Rasche ,  Stewart Young ,  Babak Movassaghi

发明人： Jurgen Weese ,  Volker Rasche ,  Stewart Young ,  Babak Movassaghi

IPC分类号： G06G7/48 ,  G06G7/58 ,  G06K9/00

CPC分类号： G06T7/11 ,  G06T7/55 ,  G06T2207/10121 ,  G06T2207/20156 ,  G06T2207/30101

摘要： The invention relates to a method for the computer-aided reconstruction of a three-dimensional anatomical object (3) from diagnostic image data. First of all, a diagnostic image data set of the object (3) is acquired. Then a seed point (5) is set, starting from which the object is reconstructed within a reconstruction volume (4). Thereafter, an adjacent point of the reconstruction volume (4) likewise belonging to the object (3) is located in accordance with a propagation criterion, which is calculated by means of a mathematical analysis of local areas (6, 7), assigned to the point concerned, of the image data set Reconstruction of the three-dimensional structure of the object (3) is then performed within the reconstruction volume (4) by multiple repetition of this method step and propagation along the located adjacent points. To apply such a reconstruction method to image data obtained by means of rotational X-ray imaging, wherein a plurality of two-dimensional projection images (1, 2) are recorded from different projection directions, the invention proposes that the propagation criterion be calculated by subjecting the local image areas (6, 7) of the two-dimensional projection images (1, 2) in each case individually to the mathematical analysis.

摘要翻译： 本发明涉及一种用于从诊断图像数据计算机辅助重构三维解剖体（3）的方法。 首先，获取对象（3）的诊断图像数据组。 然后设置种子点（5），从重建体积（4）中重建对象开始。 此后，同样属于对象（3）的重构体积（4）的相邻点根据通过局部区域（6,7）的数学分析计算的传播标准来定位，分配给 （3）的三维结构的重建然后通过该方法步骤的多次重复并且沿着定位的相邻点进行传播，在重建体积（4）内执行。 为了将这种重建方法应用于通过旋转X射线成像获得的图像数据，其中从不同的投影方向记录多个二维投影图像（1,2），本发明提出了传播标准由 在每种情况下对二维投影图像（1,2）的局部图像区域（6,7）进行数学分析。

公开(公告)号：US20060109957A1

公开(公告)日：2006-05-25

申请号：US10538444

申请日：2003-12-01

申请人： Jorn Lutjens ,  Volker Rasche

发明人： Jorn Lutjens ,  Volker Rasche

IPC分类号： A61B6/08

CPC分类号： A61B6/4441 ,  A61B6/583 ,  A61B6/587

摘要： The invention relates to an X-ray apparatus having a C-arm assembly (1) on which an X-ray source (4) and an X-ray detector are arranged opposite one another, the C-arm assembly (1) being arranged to be rotatable about a propeller axis (9) and an axis of rotation (11). To enable calibration to take place even on-line during the acquisition of projected data, respective marker arrangements (14, 15) are mounted on the X-ray source (4) and the X-ray detector (5), and a camera arrangement (12) for detecting the marker arrangements (14, 15) is arranged on the C-arm assembly (1) to allow the positions of the X-ray source (4) and the X-ray detector (5) to be determined. With this arrangement, the problem of the blocking of lines of sight between the marker arrangements (14, 15) and the camera arrangement (12) is reduced or completely avoided.

摘要翻译： 本发明涉及具有C臂组件（1）的X射线设备，X射线源（4）和X射线探测器彼此相对布置，C臂组件（1）被布置 可围绕螺旋桨轴线（9）和旋转轴线（11）旋转。 为了在获取投影数据期间甚至在线进行校准，各自的标记装置（14,15）安装在X射线源（X）和X射线检测器（5）上，并且相机装置 （12）用于检测标记装置（14,15）布置在C形臂组件（1）上，以便确定X射线源（4）和X射线检测器（5）的位置。 利用这种布置，可以减少或完全避免在标记装置（14,15）和照相机装置（12）之间阻挡视线的问题。

公开(公告)号：US06574493B2

公开(公告)日：2003-06-03

申请号：US09792097

申请日：2001-02-23

申请人： Volker Rasche ,  Georg Schmitz ,  Jörg Sabczynski ,  Waldemar Zylka ,  Johannes Jacobus Van Vaals

发明人： Volker Rasche ,  Georg Schmitz ,  Jörg Sabczynski ,  Waldemar Zylka ,  Johannes Jacobus Van Vaals

IPC分类号： A61B505

CPC分类号： A61B6/12 ,  A61B34/20 ,  A61B90/36 ,  A61B90/39 ,  A61B2034/2065 ,  A61B2090/376 ,  A61B2090/3983

摘要： The invention relates to a method enabling the localization of objects, for example surgical instruments, in interventional radiology. The method utilizes the known geometrical shape of the object to be localized in order to simulate projections therefrom for comparison with real projection images. Optimum correspondence between simulation and real image yields the desired object position and object orientation. The invention is based on digital image processing and can be used in conjunction with customary radiological diagnostic apparatus such as C-arm fluoroscopy apparatus, computed tomography apparatus or magnetic resonance tomography apparatus. Objects to be localized can be provided with markers whose spatial position yields an unambiguous projection image.

摘要翻译： 本发明涉及一种使介入放射学中的物体（例如手术器械）能够定位的方法。 该方法利用被定位的已知几何形状的物体来模拟其中的投影，以与实际投影图像进行比较。 模拟和实际图像之间的最佳对应可以产生所需的对象位置和对象方向。 本发明基于数字图像处理，并且可以与诸如C臂荧光透视装置，计算机断层摄影装置或磁共振断层摄影装置的常规放射诊断装置结合使用。 可以提供要定位的对象，其标记的空间位置产生明确的投影图像。