公开(公告)号：USD989050S1

公开(公告)日：2023-06-13

申请号：US29792246

申请日：2022-03-15

Applicant: Galvani Bioelectronics Limited

Designer： Peng Cong ,  Damiano Patron ,  Stephen O'Driscoll

Abstract: FIG. 1 is a perspective view of a planar antenna showing the claimed design;
FIG. 2 is a top view thereof;
FIG. 3 is a bottom view thereof;
FIG. 4 is a right side view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a front view thereof; and,
FIG. 7 is a rear view thereof.
The broken lines illustrate environment and portions of the antenna that form no part of the claimed design.

公开(公告)号：US20230149724A1

公开(公告)日：2023-05-18

申请号：US18153704

申请日：2023-01-12

Applicant: Galvani Bioelectronics Limited

Inventor： Eric Irwin ,  Andrew Hindmarsh ,  John Bennett

IPC: A61N1/375 ,  A61B17/3209 ,  A61N1/378 ,  A61B17/29

CPC classification number: A61N1/37518 ,  A61B17/29 ,  A61B17/3209 ,  A61N1/378 ,  A61B2018/00529

Abstract: An implantation system and methods of inserting an implant are disclosed. The method includes the step of making an incision in an abdominal wall with an instrument positioned within an abdominal cavity. The method further includes the steps of forming a pocket between a first surface of the abdominal wall and a second surface of the abdominal wall, such that the incision defines an opening into the pocket, inserting an implant through the opening and into the pocket, and closing the opening such that the implant is captured within the pocket.

公开(公告)号：US11623098B2

公开(公告)日：2023-04-11

申请号：US15733223

申请日：2018-12-11

Applicant: Galvani Bioelectronics Limited

Inventor： Gerald Edwin Hunsberger

IPC: A61N1/36 ,  A61N1/05

Abstract: There is provided a neural interface device for unidirectional stimulation of a nerve including at least one A-type nerve fiber or at least one at least partially myelinated nerve fiber. The device includes an electrode arrangement for placing on or around the nerve. The electrode arrangement includes a first electrode configured to be positively charged and a second electrode configured to be negatively charged, where the surface area of the second electrode is larger than the surface area of first electrode.

公开(公告)号：US11577080B2

公开(公告)日：2023-02-14

申请号：US15523914

申请日：2015-11-03

Applicant: GALVANI BIOELECTRONICS LIMITED ,  FACULDADE DE CIÊNCIAS MÉDICAS DA UNIVERSIDADA NOVA DE LISBOA

Inventor： Silvia Margarida Vilares Santos Conde ,  Daniel John Chew ,  Hans Jakob Kristoffer Famm ,  Maria Pedro Sucena Guarino ,  Brad Holinski ,  Sonal Patel

IPC: A61N1/36 ,  A61N1/05

Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.

公开(公告)号：US20220409889A1

公开(公告)日：2022-12-29

申请号：US17780228

申请日：2020-11-27

Applicant: Galvani Bioelectronics Limited

Inventor： Morten Hansen ,  Sebastien Ouchouche ,  Benjamin Kreil Yaffe ,  Paul Matteucci ,  Kurtis Gross

IPC: A61N1/05

Abstract: A deployment tab for deploying a neural interface device, the deployment tab comprising a first portion configured, in use, to be positioned proximal to the neural interface device; and a connector, for releasably coupling the first portion to the neural interface device, the connector being anchored to the first portion.

公开(公告)号：US20220401731A1

公开(公告)日：2022-12-22

申请号：US17872703

申请日：2022-07-25

Applicant: Galvani Bioelectronics Limited

Inventor： Daniel John Chew ,  Matteo Donega ,  Isha Gupta

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/20

Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.

公开(公告)号：US11517754B2

公开(公告)日：2022-12-06

申请号：US16610658

申请日：2018-05-04

Applicant: Galvani Bioelectronics Limited ,  Centre Nationale de La Recherche Scientifique ,  Université Côte d'Azur

Inventor： Arun Sridhar ,  Philippe Blancou ,  Nicolas Glaichenhaus

IPC: A61N1/36 ,  A61N1/05

Abstract: Modulation of neural signaling of a pancreas-related sympathetic nerve is capable of improving glycaemic control by inhibiting T cell activation or migration to the pancreas, and hence providing a way of treating or preventing type 1 diabetes.

公开(公告)号：US20220305259A1

公开(公告)日：2022-09-29

申请号：US17619561

申请日：2020-06-17

Applicant: Galvani Bioelectronics Limited

Inventor： Isha Gupta ,  Matteo Donega

IPC: A61N1/36 ,  A61N1/05

Abstract: Stimulation of neural activity in a splenic arterial nerve at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.

公开(公告)号：US11446496B2

公开(公告)日：2022-09-20

申请号：US16955393

申请日：2018-12-20

Applicant: Galvani Bioelectronics Limited

Inventor： Margarita J. Vervoordeldonk ,  Eric Irwin ,  Daniel John Chew ,  Matteo Donega ,  Cindy Cleypool ,  Isha Gupta

IPC: A61N1/00 ,  A61N1/36 ,  A61N1/05 ,  A61N1/08

Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.

公开(公告)号：US20220257932A1

公开(公告)日：2022-08-18

申请号：US17739897

申请日：2022-05-09

Applicant: GALVANI BIOELECTRONICS LIMITED

Inventor： Faisal ZAIDI ,  Sebastien OUCHOUCHE

IPC: A61N1/05

Abstract: An extravascular neural interface is disclosed including a device containing electrodes for neurostimulation of a vessel. The devices are housed in flexible substrates forming two flaps, an inner flap having a spinal portion for routing leads/conductors into the device for connection to the electrodes and an outer flap that overlaps the inner flap. The inner flap supports and positions the electrodes to be inward facing, i.e., extravascular designs. The electrodes may be circular or elliptical and include a plurality of wings for securing the electrodes within a flap.