公开(公告)号：US07888026B2

公开(公告)日：2011-02-15

申请号：US12120189

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 3 and mutated sequences thereof.

摘要翻译： 提供探针，一组探针和探针或探针载体，探针或探针组固定在其上，用于分类真菌。 探针或一组探针能够共同检测相同物种的真菌，并将这些真菌与其他物种的真菌区分开来。 探针是用于检测病原真菌DNA的寡核苷酸探针，包括SEQ ID NOS的至少一个碱基序列。 1至3及其突变序列。

公开(公告)号：US07858315B2

公开(公告)日：2010-12-28

申请号：US12119999

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 4 and mutated sequences thereof.

摘要翻译： 提供探针，一组探针和探针或探针载体，探针或探针组固定在其上，用于分类真菌。 探针或一组探针能够共同检测相同物种的真菌，并将这些真菌与其他物种的真菌区分开来。 探针是用于检测病原真菌DNA的寡核苷酸探针，包括SEQ ID NOS的至少一个碱基序列。 1至4及其突变序列。

公开(公告)号：US20090081666A1

公开(公告)日：2009-03-26

申请号：US12120177

申请日：2008-05-13

申请人： Toshifumi Fukui ,  Nobuhiro Tomatsu ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Toshifumi Fukui ,  Nobuhiro Tomatsu ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6895 ,  G01N2800/20 ,  Y10S435/975

摘要： It is intended to provide a method for identifying a causative fungus of skin disease. The method includes: simultaneously performing amplification treatments under the same conditions using primers common to plural fungal species; then simultaneously performing hybridization procedures under the same conditions using probes respectively specific to fungi; and determining the presence or absence of each fungus from the hybridization intensity of each probe.

摘要翻译： 旨在提供一种鉴定皮肤病原因真菌的方法。 该方法包括：在相同条件下同时进行扩增处理，使用多种真菌种类共有的引物; 然后在相同条件下使用分别对真菌特异的探针同时进行杂交程序; 并根据每个探针的杂交强度确定每种真菌的存在或不存在。

公开(公告)号：US20090068661A1

公开(公告)日：2009-03-12

申请号：US12120104

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/00

CPC分类号： C12Q1/689 ,  C12Q2537/143

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 4 and mutated sequences thereof.

摘要翻译： 提供探针，一组探针和探针或探针载体，探针或探针组固定在其上，用于分类真菌。 探针或一组探针能够共同检测相同物种的真菌，并将这些真菌与其他物种的真菌区分开来。 探针是用于检测病原真菌DNA的寡核苷酸探针，包括SEQ ID NOS的至少一个碱基序列。 1至4及其突变序列。

公开(公告)号：US20090011419A1

公开(公告)日：2009-01-08

申请号：US12120185

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 2 and mutated sequences thereof.

摘要翻译： 提供探针，一组探针和探针或探针载体，探针或探针组固定在其上，用于分类真菌。 探针或一组探针能够共同检测相同物种的真菌，并将这些真菌与其他物种的真菌区分开来。 探针是用于检测病原真菌DNA的寡核苷酸探针，包括SEQ ID NOS的至少一个碱基序列。 1至2及其突变序列。

公开(公告)号：US20080299578A1

公开(公告)日：2008-12-04

申请号：US12120189

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 3 and mutated sequences thereof.

公开(公告)号：US20080299577A1

公开(公告)日：2008-12-04

申请号：US12120179

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 2 and mutated sequences thereof.

公开(公告)号：US20080299576A1

公开(公告)日：2008-12-04

申请号：US12120155

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C12Q1/68 ,  C07H21/04

CPC分类号： C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 2 and mutated sequences thereof.

摘要翻译： 提供探针，一组探针和探针或探针载体，探针或探针组固定在其上，用于分类真菌。 探针或一组探针能够共同检测相同物种的真菌，并将这些真菌与其他物种的真菌区分开来。 探针是用于检测病原真菌DNA的寡核苷酸探针，包括SEQ ID NOS的至少一个碱基序列。 1至2及其突变序列。

公开(公告)号：US20080287312A1

公开(公告)日：2008-11-20

申请号：US12120100

申请日：2008-05-13

申请人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

发明人： Nobuhiro Tomatsu ,  Toshifumi Fukui ,  Nobuyoshi Shimizu ,  Atsushi Takayanagi

IPC分类号： C40B30/04 ,  C07H21/04 ,  C40B40/06

CPC分类号： C07K14/37 ,  C12Q1/6895

摘要： A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 2 and mutated sequences thereof.