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    Treating bone-related disorders with selective androgen receptor modulators
    72.
    发明申请
    Treating bone-related disorders with selective androgen receptor modulators 审中-公开
    用选择性雄激素受体调节剂治疗骨骼相关疾病

    公开(公告)号：US20060019931A1

    公开(公告)日：2006-01-26

    申请号：US10961380

    申请日：2004-10-12

    申请人： James Dalton ,  Karen Veverka ,  Jeffrey Kearbey

    发明人： James Dalton ,  Karen Veverka ,  Jeffrey Kearbey

    IPC分类号： A61K31/4704 ,  A61K31/405 ,  A61K31/66 ,  A61K31/165 ,  A61K31/32 ,  A61K31/21

    CPC分类号： A61K31/167 ,  A61K31/00 ,  A61K31/165 ,  A61K31/21 ,  A61K31/32 ,  A61K31/405 ,  A61K31/4704 ,  A61K31/66

    摘要： This invention provides method of treating, preventing, suppressing, inhibiting, or reducing the risk of developing a bone-related disorder, for example osteoporosis, osteopenia, increased bone resorption, bone fracture, bone frailty and/or loss of bone mineral density (BMD), by administering a therapeutically effective amount of a selective androgen receptor modulator (SARM) and/or its analogue, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof. The invention also provides methods of decreasing fat mass (FM) and increasing lean mass, comprising administering same.

    摘要翻译： 本发明提供了治疗，预防，抑制，抑制或降低骨相关病症发生风险的方法，例如骨质疏松症，骨质减少，增加的骨吸收，骨折，骨质脆弱和/或骨矿物质密度的丧失（BMD ），通过施用治疗有效量的选择性雄激素受体调节剂（SARM）和/或其类似物，衍生物，异构体，代谢物，药学上可接受的盐，药物产品，水合物，N-氧化物或其任何组合。 本发明还提供降低脂肪量（FM）和增加瘦肉质量的方法，包括施用它们。

    Method and system for routing calls over a packet switched computer network
    73.
    发明申请
    Method and system for routing calls over a packet switched computer network 有权
    通过分组交换计算机网络路由呼叫的方法和系统

    公开(公告)号：US20050201364A1

    公开(公告)日：2005-09-15

    申请号：US11075040

    申请日：2005-03-08

    申请人： James Dalton ,  Dmitry Isakbayev ,  Vikrant Mathur

    发明人： James Dalton ,  Dmitry Isakbayev ,  Vikrant Mathur

    IPC分类号： H04L12/28 ,  H04L12/56 ,  H04L12/66

    CPC分类号： H04L65/1046 ,  H04L45/00 ,  H04L47/10 ,  H04L47/2416

    摘要： The present invention describes how a trusted network routing authority, such as a VoIP inter-exchange carrier or clearinghouse can provide routing and secure access control across multiple network domains with a single routing and admission request. This technology can improve network efficiency and quality of service when an Internet Protocol (IP) communication transaction, such as a Voice over IP (VoIP), must be routed across multiple devices or administrative domains. This technology defines the technique of performing multiple route look-ups at the source of the call path to determine all possible routes across intermediate domains to the final destination. The VoIP inter-exchange carrier or clearinghouse then provides routing and access permission tokens for the entire call path to the call source.

    摘要翻译： 本发明描述了诸如VoIP交换运营商或结算所之类的信任网络路由机构如何通过单个路由和接纳请求来提供跨多个网络域的路由和安全访问控制。 当诸如IP语音（VoIP）的因特网协议（IP）通信事务必须跨多个设备或管理域路由时，该技术可以提高网络效率和服务质量。 该技术定义了在呼叫路径的源处执行多个路由查找以确定跨越中间域到最终目的地的所有可能路由的技术。 然后，VoIP交换运营商或交换中心为呼叫源的整个呼叫路径提供路由和访问权限令牌。